Yoshimura Kentaro

Affiliation and department：

Research field (1)： Oral medicine

Research theme for competitive and other funds (7)：

2020 - 2023 Stromal cell-derived factor1 expression on periodontal ligament cells derived from Down syndrom
2018 - 2021 Clarification of the mechanism of bone degradation by methylglyoxal and development of methods to prevent it
2016 - 2020 Development of the periodontal therapy by the stromal cell derived factor -Analysis of periodontal ligament cells derived from Down's syndrome -
2015 - 2018 On the regulatory mechanism of hard tissue metabolism by 8-nitro-cGMP
2014 - 2016 Modulation of osteoblast functions by Methylglyoxal

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Papers (47)：

Yuji Sasama, Kentaro Yoshimura, Marie Hoshino, Kiyohito Sasa, Takaaki Akaike, Masanobu Morita, Kazuyoshi Baba, Tatsuo Shirota, Yoichi Miyamoto. Supersulfides support bone growth by promoting chondrocyte proliferation in the growth plates. Journal of Oral Biosciences. 2023
Kotaro Kaneko, Yoichi Miyamoto, Tomoaki Ida, Masanobu Morita, Kentaro Yoshimura, Kei Nagasaki, Kazuki Toba, Risa Sugisaki, Hozumi Motohashi, Takaaki Akaike, et al. 8-Nitro-cGMP suppresses mineralization by mouse osteoblasts. Journal of clinical biochemistry and nutrition. 2022. 71. 3. 191-197
Motohiro Tanaka, Yoichi Miyamoto, Kiyohito Sasa, Kentaro Yoshimura, Atsushi Yamada, Tatsuo Shirota, Ryutaro Kamijo. Low oxygen tension suppresses the death of chondrocyte-like ATDC5 cells induced by interleukin-1ß. In Vitro Cellular & Developmental Biology - Animal. 2022
Kaori Ikezaki-Amada, Yoichi Miyamoto, Kiyohito Sasa, Atsushi Yamada, Mitsuhiro Kinoshita, Kentaro Yoshimura, Ryota Kawai, Fumiko Yano, Tatsuo Shirota, Ryutaro Kamijo. Extracellular acidification augments sclerostin and osteoprotegerin production by Ocy454 mouse osteocytes. Biochemical and Biophysical Research Communications. 2022. 597. 44-51
Takeyoshi Asakawa, Atsushi Yamada, Masumi Kugino, Tomokazu Hasegawa, Kentaro Yoshimura, Kiyohito Sasa, Mitsuhiro Kinoshita, Masakazu Nitta, Karin Nagata, Tomomi Sugiyama, et al. Establishment of Down's syndrome periodontal ligament cells by transfection with SV40T-Ag and hTERT. Human cell. 2021. 35. 1. 379-383

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MISC (53)：

笹清人, 吉村健太郎, 宮本洋一, 上條竜太郎. モノカルボン酸トランスポーターの骨形成および骨吸収における機能解析. 日本酸化ストレス学会学術集会プログラム・抄録集. 2021. 74th (CD-ROM)
笹清人, 吉村健太郎, 今井裕子, 山本松男, 上條竜太郎. モノカルボン酸輸送担体は骨形成と骨吸収の両者を調節する. 口腔組織培養学会誌. 2020. 29. 1. 29-30
頌彦玲子, 頌彦玲子, 笹清人, 山田篤, 宮本洋一, 吉村健太郎, 上條竜太郎. ゾレドロン酸による末梢血単球の破骨細胞分化抑制. 日本骨代謝学会学術集会プログラム抄録集(CD-ROM). 2020. 38th
瀧本玲子, 田中元博, 田中元博, 山田篤, 宮本洋一, 笹清人, 須澤徹夫, 吉村健太郎, 高見正道, 上條竜太郎. Zoledronate suppresses the differentiation of osteoclasts from human monocytes. Journal of Oral Biosciences Supplement (Web). 2020. 2020
瀧本玲子, 田中元博, 笹清人, 山田篤, 宮本洋一, 須澤徹夫, 吉村健太郎, 上條竜太郎. ゾレドロン酸はIRF8の発現誘導を介して末梢血単球の破骨細胞分化を抑制する. Journal of Oral Biosciences Supplement. 2019. 2019. 200-200

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Education (2)：

Professional career (1)：

Work history (5)：

2024/05 - 現在 Showa University School of Dentistry Department of Oral Anatomy and Developmental Biology Associate Professor
2022/08 - 現在昭和大学歯学部口腔解剖学講座講師
2019/04 - 2022/07 昭和大学歯学部口腔生化学講座講師
2012/05 - 2019/03 昭和大学歯学部口腔生化学講座助教
2010/04 - 2012/04 昭和大学歯学部口腔解剖学講座ポストドクター

Awards (2)：

2013/09 - 第25回歯科基礎医学会賞 Monocarboxylate transporter-1 is required for cell death in mouse chondrocytic ATDC5 cells exposed to interleukin-1β via late phase activation of nuclear factor κB and expression of phagocyte-type NADPH.
2010/09 - 歯科基礎医学会第52回歯科基礎医学会学術大会優秀ポスター賞(生化学部門) Monocarboxylate transpoter-1は,IL-1β刺激後の軟骨細胞で後期NF-κB活性化を起こし,NOX-2発現とそれに依存した細胞死を誘導する

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