Rchr
J-GLOBAL ID：201801006753532435   Update date: May. 17, 2024

Suzuki Susumu

スズキ スズム | Suzuki Susumu
Affiliation and department：
Aichi Medical University

About Aichi Medical University


Other affiliations (1)：
  • 高度研究機器部門  部門長
Research field  (2)： Tumor biology ,  Tumor diagnostics and therapeutics
Research keywords  (5)： Immunotherapy ,  Immune checkpoint ,  Cytotoxic T-lymphocyte ,  regulatory T-cells ,  Tumor immunology
Research theme for competitive and other funds  (15)：
  • 2024 - 2027 がん局所におけるTreg免疫抑制機序に基づく新たなTreg標的がん免疫療法の開発
  • 2022 - 2027 制御性T細胞の機能に着目した進行腎癌一次治療の選択に有用なバイオマーカーの 探索
  • 2021 - 2024 Development of novel cancer immunotheray by combining regulatory T-cell elimination and TGF-b inhibitors
  • 2021 - 2024 頸部リンパ節における腫瘍免疫環境の解明-免疫学的頸部郭清術の確立を目指して
  • 2019 - 2022 1. ゲノム編集によるFLT3変異改変ヒト白血病細胞の作製と新規治療法の探索
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Papers (60)：
  • Aya Yamamura, Moe Fujiwara, Akiko Kawade, Taiki Amano, Alamgir Hossain, Md Junayed Nayeem, Rubii Kondo, Yoshiaki Suzuki, Yasumichi Inoue, Hidetoshi Hayashi, et al. Corosolic acid attenuates platelet-derived growth factor signaling in macrophages and smooth muscle cells of pulmonary arterial hypertension. European journal of pharmacology. 2024. 973. 176564-176564
  • Susumu Suzuki, Toyonori Tsuzuki, Masato Saito, Toshihiko Ishii, Taishi Takahara, Akira Satou, Daisuke Inukai, Shunpei Yamanaka, Kazuhiro Yoshikawa, Ryuzo Ueda, et al. Regulatory T-cells activated in metastatic draining lymph nodes possibly suppress cancer immunity in cancer tissues of head and neck squamous cell cancer. Pathology international. 2024
  • Hiroki Okamoto, Kazuhiro Yoshikawa, Akiko Shimada, Rui Sano, Daisuke Inukai, Shunpei Yamanaka, Susumu Suzuki, Ryuzo Ueda, Hiromi Ueda, Yasushi Fujimoto, et al. Artesunate and cisplatin synergistically inhibit HNSCC cell growth and promote apoptosis with artesunate-induced decreases in Rb and phosphorylated Rb levels. Oncology reports. 2023. 50. 2
  • Hiromu Nakamura, Tetsuya Ogawa, Shunpei Yamanaka, Daisuke Inukai, Takashi Maruo, Taishi Takahara, Akira Satou, Toyonori Tsuzuki, Susumu Suzuki, Ryuzo Ueda, et al. Immune Status of Cervical Lymph Nodes in Head and Neck Cancer-A Surgical Oncology Perspective. Journal of personalized medicine. 2023. 13. 7
  • Shunpei Yamanaka, Susumu Suzuki, Hideaki Ito, Karnan Sivasundaram, Ichiro Hanamura, Ikuko Okubo, Kazuhiro Yoshikawa, Shoya Ono, Taishi Takahara, Akira Satou, et al. Establishment of Mucoepidermoid Carcinoma Cell Lines from Surgical and Recurrence Biopsy Specimens. International journal of molecular sciences. 2023. 24. 2
ｍore...
MISC (32)：
  • Yutaro Kondo, Taishi Takahara, Shoya Ono, Mitsuo Goto, Tetsuya Ogawa, Hideaki Ito, Akira Sato, Toyonori Tsuzuki, Kazuhiro Yoshikawa, Ryuzo Ueda, et al. Transforming growth factor-beta inhibitor is a candidate drug for immunotherapy of oral squamous cell carcinoma. CANCER SCIENCE. 2022. 113
  • Shunpei Yamanaka, Susumu Suzuki, Hideaki Ito, Shoya Ono, Yutaro Kondo, Daisuke Inukai, Hiroki Okamoto, Taishi Takahara, Toyonori Tsuzuki, Kazuhiro Yoshikawa, et al. Establishment passive culture cells derived from mucoepidermoid carcinoma. CANCER SCIENCE. 2022. 113. 1743-1743
  • Yutaro Kondo, Susumu Suzuki, Mitsuo Goto, Shoya Ono, Tetsuya Ogawa, Kazuhiro Yoshikawa, Toyonori Tsuzuki, Ryuzo Ueda. PD-L1 expression mechanisms are heterogeneous in oral cancer. CANCER SCIENCE. 2021. 112. 863-863
  • 佐野塁, 佐野塁, 鈴木進, 鈴木進, 犬飼大輔, 高原大志, 藤本保志, 都築豊徳, 上田龍三, 小川徹也. 甲状腺組織の腫瘍形成における免疫抑制環境の重要性. 日本癌治療学会学術集会(Web). 2021. 59th
  • 花村一朗, 鈴木進, 太田明伸, 村上五月, カルナン シバスンダラン, クアン ラム, 佐藤啓, 高原大志, 中村文乃, 高杉壮一, et al. PD-1 expression on lymphoma cells is associated with adverse prognosis in de novo DLBCL. 日本血液学会学術集会抄録(Web). 2021. 83rd
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Patents (5)：
  • エフェクター制御性T細胞の検出及び調製
  • KIT FOR PREPARATION OF ANTIGEN-SPECIFIC CYTOTOXIC T LYMPHOCYTE
  • METHOD FOR PRODUCING VIRUS-SPECIFIC CTL
  • CYTOTOXIC T-CELL EPITOPE PEPTIDE AND USE THEREOF Applicants
  • METHOD OF ASSYAING PHOSPHORYLATION ENZYME ACTIVITY OF CYCLIN/CDK COMPLEX
Books (12)：
  • Tregを標的としたがん免疫治療. 特集;免疫療法の進歩と問題点
    腫瘍内科, 20(2):137-142 2017
  • モガムリズマブの新しい展開
    最新医学 2016年 71巻 1号 126-32 2016
  • 抗腫瘍抗体 - がん細胞に対する抗体の現状と展望 実験医学 増刊 がん免疫療法 腫瘍免疫学の最新知見から治療法のアップデートまで
    実験医学 Vol.34 No.12 2016 122-131 2016
  • 成人T細胞白血病/リンパ腫におけるトリプトファン代謝の予後に関する意義
    臨床血液2015年56巻 11号 2295-304 2015
  • Progress in clinical use of CCR4 antibody for regulatory T cell suppression. Inflammation and Immunity in Cancer
    Springer 2015
ｍore...
Lectures and oral presentations  (60)：
  • Trametinib improves Treg selectivity of α-CCR4 mAb by regulating CCR4 xpression in CTLs induced via TCR/TGF-β signaling
    (第81回日本癌学会学術総会 2022)
  • Establishment of passive culture cells derived from mucoepidermoid carcinoma
    (第80回日本癌学会学術総会 2021)
  • Transforming growth factor β inhibitor is a candidate drug for immunotherapy of oral squamous cell carcinoma
    (2021)
  • Synergistic Effect of Venetoclax for Antibody Dependent Cell Cytotoxicity By Daratumumab
    (2020)
  • PD-L1 expression mechanisms are heterogeneous in oral cancer
    (2020)
ｍore...
Education (2)：
  • 1993 - 2001 Nagoya University School of Medicine
  • 1980 - 1984 Meijo University Faculty of Agriculture
Professional career (1)：
  • 医学博士 (名古屋大学)
Work history (8)：
  • 2023/10 - 現在 Aichi Medical University Research Creation Support Centre
  • 2020/04 - 現在 名古屋大学大学院医学系研究科 非常勤講師 (兼務)
  • 2017 - 2023/09 Aichi Medical University
  • 2014 - 2017 Aichi Medical University School of Medicine
  • 2012 - 2014 Aichi Medical University School of Medicine
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Committee career (1)：
  • 2023/01 - 現在 日本癌学会 評議員
Association Membership(s) (1)：
THE JAPANESE CANCER ASSOCIATION
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