Rchr
J-GLOBAL ID：201801006789513801
Update date: May. 12, 2024
Kiuchi Masahiro
Kiuchi Masahiro
Affiliation and department：
Research field (3)：
Systems genomics
, Immunology
, Nervous system function
Research keywords (6)：
epigenetics
, ヒストン修飾
, T細胞
, バイオインフォマティクス
, 神経免疫連関
, イメージング解析
Research theme for competitive and other funds (5)：
- 2022 - 2025 Mechanisms of epigenomic senescence and pathogenesis in pathogenic senescent helper T cells
- 2023 - 2024 病原性CD4+ TRM細胞を標的とした難治性免疫疾患に対する新規治療法の開発
- 2021 - 2022 肺線維症における組織常在性記憶CD4+ T細胞による 肺上皮細胞の恒常性制御の分子メカニズムの解明
- 2019 - 2021 Th2細胞分化過程におけるレギュロームマップ作成と新規エピゲノム制御因子の同定
- 2014 - 2019 Elucidation of pathogenic immune memory formation and maintenance
Papers (34)：
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Ami Aoki, Chiaki Iwamura, Masahiro Kiuchi, Kaori Tsuji, Atsushi Sasaki, Takahisa Hishiya, Rui Hirasawa, Kota Kokubo, Sachiko Kuriyama, Atsushi Onodera, et al. Suppression of Type I Interferon Signaling in Myeloid Cells by Autoantibodies in Severe COVID-19 Patients. Journal of clinical immunology. 2024. 44. 4. 104-104
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Ryo Hatano, Eunyoung Lee, Hiromi Sato, Masahiro Kiuchi, Kiyoshi Hirahara, Yoshimi Nakagawa, Hitoshi Shimano, Toshinori Nakayama, Tomoaki Tanaka, Takashi Miki. Hepatic ketone body regulation of renal gluconeogenesis. Molecular Metabolism. 2024. 101934-101934
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Shigeru Tanaka, Takuya Yamamoto, Arifumi Iwata, Masahiro Kiuchi, Kota Kokubo, Tomohisa Iinuma, Takahiro Sugiyama, Toyoyuki Hanazawa, Kiyoshi Hirahara, Kei Ikeda, et al. Single-cell RNA sequencing of submandibular gland reveals collagen type XV-positive fibroblasts as a disease-characterizing cell population of IgG4-related disease. Arthritis research & therapy. 2024. 26. 1. 55-55
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Jin Kumagai, Masahiro Kiuchi, Kota Kokubo, Hiroyuki Yagyu, Masahiro Nemoto, Kaori Tsuji, Ken Nagahata, Atsushi Sasaki, Takahisa Hishiya, Miki Onoue, et al. The USP7-STAT3-granzyme-Par-1 axis regulates allergic inflammation by promoting differentiation of IL-5-producing Th2 cells. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 49. e2302903120
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Atsushi Onodera, Kota Kokubo, Mikiko Okano, Miki Onoue, Masahiro Kiuchi, Chiaki Iwamura, Tomohisa Iinuma, Motoko Y. Kimura, Nobuyuki Ebihara, Toyoyuki Hanazawa, et al. Pathogenic helper T cells as the novel therapeutic targets for immune-mediated intractable diseases. Pharmacology & Therapeutics. 2023. 247. 108445-108445
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MISC (28)：
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尾上 美樹, 平原 潔, 木内 政宏, 岡野 美樹子, 松田 彰, 中山 俊憲, 海老原 伸行. 慢性炎症で誘導される角膜混濁を伴った角膜血管新生のマウスモデルの解析. 日本眼科学会雑誌. 2023. 127. 臨増. 174-174
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尾上美樹, 尾上美樹, 岡野美樹子, 岡野美樹子, 木内政宏, 海老原伸行, 中山俊憲, 平原潔. The mechanisms of severe itch in allergic conjunctivitis. 月刊臨床免疫・アレルギー科. 2023. 80. 2
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木内政宏, 平原潔. Cross-talk between T cells and the nervous system. 月刊臨床免疫・アレルギー科. 2023. 80. 5
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横山美樹子, 横山美樹子, 尾上美樹, 尾上美樹, 木内政宏, 平原潔, 中山俊憲, 海老原伸行. 慢性アレルギー性結膜炎における病原性記憶型Th2細胞の関わり~神経-免疫連関による“病的痒み”の誘導~. 日本眼科アレルギー学会学術集会プログラム・抄録集. 2023. 6th
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横山美樹子, 横山美樹子, 尾上美樹, 尾上美樹, 木内政宏, 平原潔, 中山俊憲, 海老原伸行. Single-Cell Immune Profilling of Vernal Keratoconjunctivitis. 日本眼科学会雑誌. 2022. 126
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Patents (1)：
Books (1)：
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基礎から学ぶ免疫学
羊土社 2023 ISBN:9784758121682
Lectures and oral presentations (17)：
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The USP7-STAT3-granzyme-Par-1 axis regulates allergic inflammation by promoting differentiation of IL-5-producing Th2 cells
(第52回 日本免疫学会学術集会 2024)
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The effect of tissue hypoxia on the immune system in chronic inflammatory lung diseases Presenter.
(International Symposium for Future Mucosal Vaccines: Safeguards and Innovations against Infectious Diseases 2023)
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Expanding Pulmonary Neuroendocrine Cells Show Heterogeneity in Chronic Airway Inflammation.
(International Symposium for Future Mucosal Vaccines: Safeguards and Innovations against Infectious Diseases 2023)
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Nematode ascarosides attenuate mammalian type 2 inflammatory responses by enhancing IL-10 production in interstitial macrophage
(International Symposium for Future Mucosal Vaccines: Safeguards and Innovations against Infectious Diseases 2023)
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Role of amphiregulin-producing pathogenic T helper 2 cells in the fibrotic responses in eosinophilic esophagitis.
(International Symposium for Future Mucosal Vaccines: Safeguards and Innovations against Infectious Diseases 2023)
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Education (3)：
- 2014 - 2018 Chiba University Graduate School of Medical and Pharmaceutical Sciences
- 2013 - 2013 Nihon University Graduate School of Bioresource Sciences
- 2007 - 2013 Nihon University College of Bioresource Sciences Department of Veterinary Medicine
Professional career (2)：
- Doctor of Medical Science (Chiba University)
- Bachelor of Veterinary Medicine (Nihon University)
Work history (1)：
- 2018/04 - 現在 Chiba University
Awards (4)：
- 2022/12 - 日本免疫学会 ベストポスター賞
- 2021/03 - 千葉大学 第六回千葉大学医学部スカラーシップ指導者賞
- 2016/03 - 千葉大学 治療学CHIBAイノベーション人材養成プログラム優秀学生賞
- 2014/06 - 日本大学獣医学会 学会賞(基礎研究分野)
Association Membership(s) (1)：
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