Research field (1)：
Bio-, chemical, and soft-matter physics
Research theme for competitive and other funds (3)：
2021 - 2024 Aggregation process of amyloid-beta peptides on a membrane on a lipid membrane studied by computer simulation
2016 - 2019 Oligomer formation of amyloid-beta studied by new constant pH simulations
2012 - 2015 Oligomerization of amyloid beta-peptides studies by computer simulations
Papers (51)：
Hisashi Okumura, Satoru G. Itoh, Heishun Zen, Kazuhiro Nakamura. Dissociation process of polyalanine aggregates by free electron laser irradiation. PLOS ONE. 2023. 18. 9. e0291093-e0291093
Maho Yagi-Utsumi, Satoru G. Itoh, Hisashi Okumura, Katsuhiko Yanagisawa, Koichi Kato, Katsuyuki Nishimura. The Double-Layered Structure of Amyloid-β Assemblage on GM1-Containing Membranes Catalytically Promotes Fibrillization. ACS Chemical Neuroscience. 2023. 14. 15. 2648-2657
Daiki Fukuhara, Masataka Yamauchi, Satoru G. Itoh, Hisashi Okumura. Ingenuity in performing replica permutation: How to order the state labels for improving sampling efficiency. JOURNAL OF COMPUTATIONAL CHEMISTRY. 2023. 44. 4. 534-545
Satoru G Itoh, Maho Yagi-Utsumi, Koichi Kato, Hisashi Okumura. Key Residue for Aggregation of Amyloid-β Peptides. ACS chemical neuroscience. 2022. 13. 22. 3139-3151
HISASHI OKUMURA, Satoru Itoh. Molecular Dynamics Simulation Studies on the Aggregation of Amyloid-β Peptides and Their Disaggregation by Ultrasonic Wave and Infrared Laser Irradiation. Molecules. 2022
S. G. Itoh, H. Okumura. Oligomerization pathway of A beta fragments by the Hamiltonian replica-permutation method. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2017. 46. S218-S218
S. G. Itoh, H. Okumura. Oligomerization process of A beta(29-42) by Coulomb replica-permutation MD simulations. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2015. 44. S147-S147
H. Okumura, S. G. Itoh. Nonequilibrium molecular dynamics simulations of amyloid disruption by ultrasonic cavitation. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2015. 44. S207-S207
OKUMURA Hisashi, Itoh Satoru G. 19aCT-4 Fluctuation and structure of Aβ amyloid fibril by molecular dynamics simulations. Meeting Abstracts of the Physical Society of Japan. 2015. 70. 3015-3015
