Rchr
J-GLOBAL ID：201801006807633194   Update date: Nov. 15, 2024

Masatoshi Ohga

オオガ マサトシ | Masatoshi Ohga
Affiliation and department：
Azabu University

About Azabu University


Job title： Lecturer
Research field  (3)： Animals: biochemistry, physiology, behavioral science ,  Laboratory animal science ,  Zoological sciences
Research keywords  (2)： Round spermatid injection (ROSI) ,  個体形成能
Research theme for competitive and other funds  (15)：
  • 2024 - 2027 受精後たった1日の間に生じるエピジェネティックな記憶の次世代への継承
  • 2023 - 2027 Improving Developmental Potential of ROSI-derived Zygotes via Elimination of Inherited Epigenome from Round Spermatids
  • 2024 - 2026 受精卵の代謝による発生制御とその応用を目指して
  • 2024 - 2025 マウス1細胞期胚におけるセリン代謝による発生制御機構とその機能の解明
  • 2023 - 2025 マウス円形精子細胞注入胚のエピゲノム改変による出産成績改善の試み
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Papers (33)：
  • Masatoshi Ooga. Chromatin structure in totipotent mouse early preimplantation embryos. The Journal of reproduction and development. 2024
  • Yasuyuki Kikuchi, Daiyu Ito, Sayaka Wakayama, Masatoshi Ooga, Teruhiko Wakayama. Time-lapse observation of mouse preimplantation embryos using a simple closed glass capillary method. Scientific reports. 2023. 13. 1. 19893-19893
  • Masatoshi Ooga, Yasuyuki Kikuchi, Daiyu Ito, Kousuke Kazama, Rei Inoue, Mizuki Sakamoto, Sayaka Wakayama, Teruhiko Wakayama. Aberrant histone methylation in mouse early preimplantation embryos derived from round spermatid injection. Biochemical and Biophysical Research Communications. 2023
  • Li Ly Yang, Daiyu Ito, Natsuki Ushigome, Sayaka Wakayama, Masatoshi Ooga, Teruhiko Wakayama. A novel, simplified method to prepare and preserve freeze-dried mouse sperm in plastic microtubes. The Journal of reproduction and development. 2023. 69. 4. 198-205
  • Akihiko Sakashita, Masatoshi Ooga, Kai Otsuka, So Maezawa, Chikara Takeuchi, Sayaka Wakayama, Teruhiko Wakayama, Satoshi H Namekawa. Polycomb protein SCML2 mediates paternal epigenetic inheritance through sperm chromatin. Nucleic Acids Research. 2023
ｍore...
MISC (29)：
  • 杉田陽美季, 財部駿介, 川田由以, 影山敦子, 井上梓, 甲斐義輝, 山下直樹, 大我政敏, 大我政敏, 村上裕信, et al. マウス受精時のPLCζを介したCa2+オシレーションは初期胚における正常な染色体分配に重要である. Journal of Mammalian Ova Research. 2024. 41. 1
  • ITO Daiyu, WAKAYAMA Sayaka, EMURA Rina, OOGA Masatoshi, WAKAYAMA Teruhiko. Mouse offspring obtained from freeze dried spermatozoa after transportation via postcard. The Journal of Reproduction and Development Supplement. 2021. 114. OR-43-OR-43
  • EMURA Rina, WAKAYAMA Sayaka, ITO Daiyu, OOGA Masatoshi, WAKAYAMA Teruhiko. Effect of sperm pre-incubation period on the quality of freeze-dried spermatozoa. The Journal of Reproduction and Development Supplement. 2021. 114. P-86-P-86
  • USHIGOME Natsuki, WAKAYAMA Sayaka, ITO Daiyu, OOGA Masatoshi, WAKAYAMA Teruhiko. Production of offspring from non-frozen vacuum dried spermatozoa. The Journal of Reproduction and Development Supplement. 2021. 114. P-87-P-87
  • INOUE Rei, KIKUCHI Yasuyuki, WAKAYAMA Sayaka, WAKAYAMA Teruhiko, OOGA Masatoshi. Evaluation of the developmental potential of early mouse preimplantation embryos using chromatin looseness measured by live imaging. The Journal of Reproduction and Development Supplement. 2021. 114. P-47-P-47
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Lectures and oral presentations  (9)：
  • 受精後1日の代謝撹乱が当代の胚発生および次世代に及ぼす影響
    (第96回日本生化学会 1S13m「環境因子による世代間伝播の生化学」 2024)
  • 円形精子細胞由来雄性前核に異常なヒストン 修飾を引き起こすヒストン変異体の探索
    (日本生殖発生医学会 第15回学術集会 2020)
  • マウス1細胞期胚のクロマチン構造の"緩み"におけるParental asymmetryの形成機構について
    (日本生殖発生医学会 第15回学術集会 2020)
  • マウスROSI胚の雄性前核におけるエピジェネティックな異常とTSA処理が及ぼす影響
    (日本生殖発生医学会 第15回学術集会 2020)
  • Mechanisms of the establishment for parental asymmetric chromatin structure in mouse zygotes
    (The second international conference on cell reprogramming and reproductive biotechnology 2019)
ｍore...
Education (3)：
  • 2009 - 2012 東京大学 Graduate school of frontier sciences Department of integrated bioscience
  • 2005 - 2007 The University of Tokyo Graduate School of Frontier Sciences
  • 2001 - 2005 Meiji University School of Agriculture Department of Agricultural Chemistry
Professional career (1)：
  • Doctor of Philosophy (The University of Tokyo)
Work history (8)：
  • 2022/04 - 現在 Azabu University Lecturer
  • 2021/07 - 現在 University of California Davis Visiting Scientist
  • 2021/04 - 現在 Tohoku University Institute of Development, Aging and Cancer
  • 2023/06 - 2023/07 Max Planck Institute Biochemistry
  • 2019/04 - 2022/03 山梨大学 大学院 総合研究部 生命環境学域 生命農学系 (生命工学) 助教
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Awards (6)：
  • 2023/09 - Society of Reproduction and Development Study of Chromatin Structure in Mouse Zygotes
  • 2020/03 - 日本生殖発生医学会 学術奨励賞 マウス1細胞期胚のクロマチン構造の"緩み”におけるParental asymmetryの形成機構について
  • 2016/09 - 日本繁殖生物学会 Journal of Reproduction and Development Outstanding Paper Award 2015 Japan
  • 2016/02 - 第一回核移植研究会 John Gurdon Poster Award Involvement of Chd9 in loosened chromatin structure in growing oocytes
  • 2014/08 - 日本繁殖生物学会 優秀発表賞(口頭発表部門 ) Analysis of chromatin structure in mouse preimplantation embryos by fluorescent recovery after photobleaching (FRAP)
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Association Membership(s) (1)：
日本繁殖生物学会
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