Uchimaru Kaoru

ウチマルカオル | Uchimaru Kaoru

Affiliation and department：

Research field (1)： Hematology and oncology

Research theme for competitive and other funds (18)：

2023 - 2025 ゲノム情報を基盤としたHTLV-1感染症の病態形成機序の解明及び発症リスク予知アルゴリズム開発に関する総合的研究
2016 - 2020 Research on risk factors for the development of ATL: Long-term cohort study of HTLV-1-infected individuals.
2014 - 2017 Integrated analysis of abnormal expression profiles that define phenotype of ATL cells
2011 - 2014 Oncogene addiction of ATL cells and abnormal Polycomb-miRNA-signal transduction
2011 - 2012 Analysis of relationship between nuclear segmentation and gene expression using neutrophils and ATL cells

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Papers (169)：

Koji Jimbo, Toyotaka Kawamata, Yoshihiro Inamoto, Ayumu Ito, Kazuaki Yokoyama, Aki Sato, Takahiro Fukuda, Kaoru Uchimaru, Yasuhito Nannya. Flow cytometric profiles with CD7 and CADM1 in CD4+ T cells are promising indicator for prognosis of aggressive ATL. Blood advances. 2024
Makoto Yamagishi, Yuta Kuze, Seiichiro Kobayashi, Makoto Nakashima, Satoko Morishima, Toyotaka Kawamata, Junya Makiyama, Kako Suzuki, Masahide Seki, Kazumi Abe, et al. Mechanisms of action and resistance in histone methylation-targeted therapy. Nature. 2024
Koji Jimbo, Makoto Yamagishi, Yutaka Suzuki, Kako Suzuki, Motoko Mizukami, Kazuaki Yokoyama, Aki Sato, Tokiko Nagamura-Inoue, Yasuhito Nannya, Kaoru Uchimaru. Progression of adult T-cell leukemia/lymphoma from smoldering to acute type due to branched subclonal evolution. EJHaem. 2023. 4. 4. 1188-1190
水上素子, 石垣知寛, 大見山茜, 小森大輔, 永井悦子, 下坂浩則, 神保光児, 南谷泰仁, 内丸薫, 長村登紀子. くすぶり型から急性転化したATL症例における異常リンパ球の形態変化. 日本臨床検査医学会誌. 2023. 71. 補冊. 230-230
神保光児, 川俣豊隆, 稲本賢弘, 横山和明, 佐藤亜紀, 福田隆浩, 内丸薫, 南谷泰仁. CD7とCADM1を用いたフローサイトメトリープロファイルはATL臨床経過を反映し予後を推定する. 日本血液学会学術集会. 2023. 85回. 539-539

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MISC (130)：

WANG Yu, OKITA Mizuho, OGATA Masao, HAGIWARA Shotaro, YASUI Hiroshi, UCHIMARU Kaoru, KOH Kiryan, UTSUNOMIYA Atae, WATANABE Toshiki, WATANABE Toshiki, et al. Identification and validation of the novel ATL biomarkers. 日本HTLV-1学会学術集会. 2023. 9th
池辺詠美, 池辺詠美, 松岡佐保子, 中島誠, 村岡弘美, 吉村千穂子, 山岸誠, 内丸薫, 伊波英克, 内丸薫, et al. Investigation of the usefulness of NAE inhibitors as novel ATL therapies. 日本HTLV-1学会学術集会. 2023. 9th
池辺詠美, 池辺詠美, 松岡佐保子, 中島誠, 村岡弘美, 吉村千穂子, 山岸誠, 内丸薫, 内丸薫, 伊波英克, et al. Efficacy of NEDD8 Activating Enzyme Inhibitors in HTLV-1-related disease. 日本HTLV-1学会学術集会. 2022. 8th
岩松見, 中島誠, 村田めぐみ, 山岸誠, 手塚健太, 浜口功, 明里宏文, 内丸薫. 二次リンパ組織におけるSTLV-1感染細胞の局在とその意義. 日本HTLV-1学会学術集会. 2021. 7th
山岸誠, 鈴木穣, 窪川美雪, 久世裕太, 横溝明香里, 鈴木絢子, 小林誠一郎, 中島誠, 宇都宮與, 森島聡子, et al. 多層シングルセルプラットフォームによるクローン構造解析とTCR経路変異の生物学的意義の検討. 日本癌学会総会記事. 2020. 79回. OE7-7

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Professional career (1)：

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