Rchr
J-GLOBAL ID:201801006923140146
Update date: Sep. 05, 2024
Takeshita Noriko
タケシタ ノリコ | Takeshita Noriko
Affiliation and department:
Research field (3):
Physiology
, Clinical pharmacy
, Home economics, lifestyle science
Research keywords (6):
claudin
, tight junction
, NaCl吸収
, transporter
, NHE3
, gastrointestin
Research theme for competitive and other funds (8):
- 2021 - 2026 Elucidation of the physiological significance of the energy sensing system in the proximal small intestine
- 2021 - 2024 腹膜タイト結合におけるクローディン15の生理学的意義の検討
- 2019 - 2021 Elucidation of the physiological significance of Na transporter coupling partners using the organoid
- 2019 - 2020 Elucidation of the intestinal NaCl absorption mechanism using mini-guts
- 2017 - 2020 小腸グルコース吸収機構における能動から拡散輸送へのモード変化の生理学的意義の検討
- 2018 - 2019 バリア蛋白質によるNa輸送調節機構の解明
- 2018 - 2019 上皮バリア蛋白質による新規腸管Na代謝調節機構の解明
- 2017 - 2019 慢性腎臓病治療の新たなターゲットとなるNa+吸収輸送体の輸送機構の解明
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Papers (36):
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Chisato Nakamura, Noriko Ishizuka, Kanako Yokoyama, Yuyu Yazaki, Fumiya Tatsumi, Naotaka Ikumi, Wendy Hempstock, Akira Ikari, Yuta Yoshino, Hisayoshi Hayashi. Regulatory mechanisms of glucose absorption in the mouse proximal small intestine during fasting and feeding. Scientific Reports. 2023. 13. 1
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Wendy Hempstock, Nozomi Nagata, Noriko Ishizuka, Hisayoshi Hayashi. The effect of claudin-15 deletion on cationic selectivity and transport in paracellular pathways of the cecum and large intestine. Scientific reports. 2023. 13. 1. 6799-6799
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Noriko Ishizuka, Mina Nagahashi, Yuina Mochida, Wendy Hempstock, Nozomi Nagata, Hisayoshi Hayashi. Na+-dependent intestinal glucose absorption mechanisms and its luminal Na+ homeostasis across metamorphosis from tadpoles to frogs. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2023
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Kazuya Tanifuji, Yuji Shiozaki, Megumi Koike, Minori Uga, Aoi Komiya, Mizuki Miura, Ayami Higashi, Takaaki Shimohata, Akira Takahashi, Noriko Ishizuka, et al. Effects of EOS789, a novel pan-phosphate transporter inhibitor, on phosphate metabolism : Comparison with a conventional phosphate binder. The journal of medical investigation : JMI. 2023. 70. 1.2. 260-270
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Mikio Furuse, Daiki Nakatsu, Wendy Hempstock, Shiori Sugioka, Noriko Ishizuka, Kyoko Furuse, Taichi Sugawara, Yugo Fukazawa, Hisayoshi Hayashi. Reconstitution of functional tight junctions with individual claudin subtypes in epithelial cells. Cell structure and function. 2022
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MISC (62):
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林 久由, 中村 千紗都, 石塚 典子, Hempstock Wendy. マウス小腸における絶食と食餌による部位特異的なグルコース吸収調節機構. 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [1P-239]
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石塚 典子, 矢崎 友結, 栗原 史弥, 林 久由. 腹膜中皮におけるタイト結合タンパク質クローディン15の役割. 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [P-386]
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伊久美 直毅, 杉岡 汐里, 石塚 典子, 古瀬 幹夫, 林 久由. マウス腸管における三細胞タイト結合タンパク質アンギュリン1の役割の検討. 日本生理学雑誌. 2021. 83. 2. 23-23
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石塚 典子, 伊久美 直毅, 林 久由. 消化管NaCl吸収におけるNa+/H+交換輸送体NHE3の役割の検討. 日本生理学雑誌. 2021. 83. 2. 22-22
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廣田 智恵子, 高階 優衣, 眞鍋 綾, 石塚 典子, 林 久由, 田渕 圭章, 松永 俊之, 五十里 彰. 大腸塩分吸収の調節における細胞間接着分子クローディン-7の役割. 日本生理学雑誌. 2021. 83. 2. 22-22
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Lectures and oral presentations (72):
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Luminal Na+ concentration is preserved in claudin-15 knockout mice fed a high Na+ diet.
(Europhysiology 2022 2022)
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Claudin-15 is the molecule responsible for the conductance and permselectivity of the murine cecum and large intestinal epithelia.
(Europhysiology 2022 2022)
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he effect of fasting on sodium-dependent glucose absorption in the mouse proximal small intestine.
(Europhysiology 2022 2022)
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クローディン15欠損による消化及びエネルギー代謝の影響
(第99回日本生理学会大会 2022)
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腸管上皮細胞の分化によるクローディン-2発現とクローディン-7発現の逆相関
(第99回日本生理学会大会 2022)
more...
Education (2):
- 2004 - 2006 University of Shizuoka Graduate School of Nutritional and Environmental Sciences
- 2000 - 2004 University of Shizuoka School of Food and Nutritional Sciences Department of Nutritional Science
Professional career (1):
Work history (5):
- 2023/04 - 現在 University of Shizuoka, Junior College Department of Liberal Arts
- 2015/04 - 2023/03 University of Shizuoka School of Food and Nutritional Sciences
- 2014/04 - 2015/03 Tokai Gakuin University Faculty of Health and Welfare
- 2009/04 - 2014/03 Kiryu University Faculty of Health Care, Department of Nutrition
- 2006/04 - 2009/03 Kamakura Women's University Faculty of Family and Consumer Sciences, Department of Nutrition and Dietetics
Committee career (7):
Awards (1):
- 2019/11 - 日本動物実験代替法学会第32回大会 優秀演題賞 腸オルガノイドを用いたNa+吸収輸送活性の測定
Association Membership(s) (2):
JAPANESE SOCIETY FOR ALTERNATIVES TO ANIMAL EXPERIMENTS
, THE PHYSIOLOGICAL SOCIETY OF JAPAN
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