Rchr
J-GLOBAL ID：201801006994637084   Update date: May. 01, 2024

Kasai Shinya

シンヤ カサイ | Kasai Shinya
Affiliation and department：
Tokyo Metropolitan Institute of Medical Science Department of Psychiatry and Behavioral Sciences

About Tokyo Metropolitan Institute of Medical Science Department of Psychiatry and Behavioral Sciences


Job title： Chief Researcher
Research field  (5)： Psychiatry ,  Anesthesiology ,  Forensic medicine ,  Neuropathology ,  Pharmacology
Research keywords  (14)： smoking ,  postmorten brain ,  Wild-derived mice ,  Transciptome ,  Alcohol ,  Opioids ,  Glycosylation ,  Proopiomelanocortin ,  Opioid receptor ,  Tuberous sclerosis ,  Autism spectrum disorder ,  Neuropathic pain ,  Chronic pain ,  Drug addiction
Research theme for competitive and other funds  (19)：
  • 2019 - 2024 Mechanisms of gene regulation intrinsic for human brain in opioid adverse efects
  • 2016 - 2020 タンパク質合成・分解異常に着目した自閉症スペクトラム発症の分子機序解明
  • 2016 - 2019 ニコチンが自閉症の発症と治療に及ぼす効果の解明
  • 2016 - 2019 疼痛の慢性化を生み出す脳内遺伝子メカニズムの解明
  • 2016 - 2019 野生由来コンソミックマウス系統群を用いたアルコール嗜好性の遺伝子メカニズム解析
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Papers (65)：
  • Daisuke Nishizawa, Ryozo Morino, Rie Inoue, Seii Ohka, Shinya Kasai, Junko Hasegawa, Yuko Ebata, Kyoko Nakayama, Hiroyuki Sumikura, Masakazu Hayashida, et al. Genome-Wide Association Study Identifies Novel Candidate Variants Associated with Postoperative Nausea and Vomiting. Cancers. 2023. 15. 19. 4729-4729
  • Daisuke Nishizawa, Tsutomu Mieda, Miki Tsujita, Hideyuki Nakagawa, Shigeki Yamaguchi, Shinya Kasai, Junko Hasegawa, Kyoko Nakayama, Yuko Ebata, Akira Kitamura, et al. Genome-Wide Association Study Identifies Genetic Polymorphisms Associated with Estimated Minimum Effective Concentration of Fentanyl in Patients Undergoing Laparoscopic-Assisted Colectomy. International Journal of Molecular Sciences. 2023. 24. 9. 8421-8421
  • Yoshinori Aoki, Daisuke Nishizawa, Seii Ohka, Shinya Kasai, Hideko Arita, Kazuo Hanaoka, Choku Yajima, Masako Iseki, Jitsu Kato, Setsuro Ogawa, et al. Rs11726196 Single-Nucleotide Polymorphism of the Transient Receptor Potential Canonical 3 (TRPC3) Gene Is Associated with Chronic Pain. International Journal of Molecular Sciences. 2023. 24. 2. 1028-1028
  • Kazumasu Sasaki, Roberto Rabozzi, Shinya Kasai, Kazutaka Ikeda, Tatsuya Ishikawa. Fentanyl-induced muscle rigidity in a dog during weaning from mechanical ventilation after emergency abdominal surgery: A case report. Veterinary Medicine and Science. 2022
  • Hirofumi Kashii, Shinya Kasai, Atsushi Sato, Yoko Hagino, Yasumasa Nishito, Toshiyuki Kobayashi, Okio Hino, Masashi Mizuguchi, Kazutaka Ikeda. Tsc2 mutation rather than Tsc1 mutation dominantly causes a social deficit in a mouse model of tuberous sclerosis complex. 2022
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MISC (86)：
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Patents (1)：
Books (2)：
  • 緩和医療-痛みの理解から心のケアまで
    東京大学出版会 2010 ISBN:4130634011
  • 緩和医療 : 痛みの理解から心のケアまで
    東京大学出版会 2010 ISBN:9784130634014
Lectures and oral presentations  (8)：
  • Transcriptome profiling of dopamine-deficient mouse brain.
    (2017)
  • Association of Proopioimeranocortin gene polymorphism with vulnerability to alcohol dependence in Japanese.
    (5th Congress of Asian College of Neuropsychopharmacology (AsCNP 2017) 2017)
  • Molecular mechanisms underlying individual differences in pain and analgesic sensitivity.
    (5th Congress of Asian College of Neuropsychopharmacology (AsCNP 2017) 2017)
  • Opioid receptor-related genes associated with smoking/tobacco use in Japanese.
    (17th Pacific Rim College of Psychiatrists Scientific Meeting (PRCP2016) 2016)
  • Genetic association with smoking/tobacco use in Japanese.
    (4th Congress of Asian College of Neuropsychopharmacology (AsCNP2015) 2015)
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Professional career (3)：
  • B.Eng. (Department of Bioengineering, Tokyo Institute of Technology)
  • M.Eng. (Department of Bioengineering, Tokyo Institute of Technology)
  • Ph.D. (Institute for Frontier Medical Sciences, Kyoto University)
Committee career (3)：
  • 2016 - 現在 日本神経精神薬理学会 編集委員会
  • 2012 - 現在 日本アルコール・薬物医学会 評議員
  • 2012 - 現在 日本神経精神薬理学会 評議委員
Awards (5)：
  • 2014/06 - The Japanese Society of Neuropsychopharmacology JSNP Excellent Presentation Award for CINP2014 Reduced supraspinal nociceptive responses and distinct gene expression profile in CXBH recombinant inbred mice.
  • 2013/09 - The Japanese Society of Neuropsychopharmacology JSNP Excellent Presentation Award for AsCNP2013 Association between an opioid receptor-related gene polymorphism and smoking in Japanese.
  • 2010/06 - The Japanese Society of Neuropsychopharmacology JSNP Excellent Presentation Award for CINP2010 Associations between nucleotide sequence differences in the Oprm1 gene and sensitivity to morphine in wild-derived inbred mouse strains.
  • 2005/09 - Korea Society of Biological Psychiatry Travel Award Genetic analyses of mouse mu-opioid receptors: implication of 3'UTR difference in opiate sensitivity.
  • 2005/07 - The Japanese Society of Neuropsychopharmacology Outstanding Paper Award Involvement of 3’UTR of mu opioid receptor gene in morphine analgesia.
Association Membership(s) (6)：
The International College of Neuropsychopharmacology ,  Asian College of Neuropsychopharmacology ,  Japanese Narcotics Research Conference ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  JAPANESE MEDICAL SOCIETY OF ALCOHOL AND ADDICTION STUDIES ,  THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY
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