Research field (2)：
Structural biochemistry
, Virology
Research keywords (5)：
数理モデル
, Accessory protein
, X-ray crystallographic analysis
, Paramyxovirus
, Drug discovery
Research theme for competitive and other funds (18)：
2024 - 2027 Inhibitors of kynurenine production: drug development of non-conventional IDO1 inhibitor A and elucidation of mechanism of action by cpd B.
2023 - 2026 Development of dual-action antimicrobial agents effective against antimicrobial resistant bacteria
2020 - 2023 Structural basis of innate immune evasion by Paramyxovirus C protein involving the binding to the novel counterpart
2018 - 2021 RNAウイルスにおける新規標的因子IFN受容体を介した自然免疫回避機構
2016 - 2019 Elucidation of interactions between paramyxoviral infection and host innate immunity
Erika Inoue, Shiyo Minatozaki, Sachi Shimizu, Sayaka Miyamoto, Misato Jo, Junjun Ni, Hidetoshi Tozaki-Saitoh, Kosuke Oda, Saori Nonaka, Hiroshi Nakanishi. Human β-Defensin 3 Inhibition of P. gingivalis LPS-Induced IL-1β Production by BV-2 Microglia through Suppression of Cathepsins B and L. Cells. 2024. 13. 3. 283-283
Basirat Mojisola Lawal-Ayinde, Tomoko Morita, Kosuke Oda, Tanuza Nazmul, Miuko Kurose, Toshihito Nomura, Akima Yamamoto, Akifumi Higashiura, Tomoyuki Akita, Junko Tanaka, et al. Virus purification highlights the high susceptibility of SARS-CoV-2 to a chlorine-based disinfectant, chlorous acid. PLOS ONE. 2023. 18. 7. e0288634-e0288634
Masaya Fukushi, Ryosuke Ohsawa, Yasushi Okinaka, Daisuke Oikawa, Tohru Kiyono, Masaya Moriwaki, Takashi Irie, Kosuke Oda, Yasuhiro Kamei, Fuminori Tokunaga, et al. Optineurin deficiency impairs autophagy to cause interferon beta overproduction and increased survival of mice following viral infection. PLOS ONE. 2023. 18. 6. e0287545-e0287545
Oda K, Sakaguchi T, Matoba. Catalytic Mechanism of DcsB: Arginase Framework Used for Hydrolyzing Its Inhibitor. Protein Science. 2022. 31. 6. e4338
Oda, Kosuke, Sakaguchi, Takemasa, Matoba, Yasuyuki. Crystal structure of O-ureidoserine racemase found in the D-cycloserine biosynthetic pathway. Proteins. 2022. 90. 4. 912-918
Structural Studies of Enzymes Utilized for the Stereoselective Biosynthesis of D-Cycloserine
Studies in Natural Products Chemistry, Elsevier Science Publishers
Lectures and oral presentations (52)：
Catalytic Mechanism of DcsB: Arginase Framework Used for Hydrolyzing Its Inhibitor
(IUMS2022 2022)
Similar but different catalytic mechanism of Nomega-hydroxy-L-arginine hydrolase: arginase framework used for hydrolyzing its inhibitor
(The 36th Annual Symposium of The Protein Society 2022)
Significance of the association of the C protein with Alix for the budding of Sendai virus on the basis of the crystal structure
(IUMS2020, XVIII International Congress of Virology 2020)
division of biotechnology
, The Japanese Society for Virology
, The Pharmaceutical Society of Japan
, Protein Scinence Society of Japan
, The Society for Biotechnology, Japan
