OHIRA MASAHIRO

オオヒラマサヒロ | OHIRA MASAHIRO

Affiliation and department：
Job title：助教

Research field (1)： Digestive surgery

Research theme for competitive and other funds (14)：

2023 - 2028 切除不能な肝門部領域胆管癌に対する生体肝移植で治癒に至る分子生物学的特性の解明
2023 - 2026 Investigation of impaired liver resident NK cell function in metabolic syndrome and development of an integrative therapy
2022 - 2025 Elucidation of the mechanism of cancer immune evasion by glycan-responsive B cells and development of regulatory methods
2020 - 2023 Analysis of the regulatory mechanism of liver resident NK cell function through aortic calcification factor (apolipoprotein E)
2020 - 2021 Elucidation of novel rejection mechanism after HLA-matched transplantation using allogeneic iPS cells

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Papers (178)：

Yuki Imaoka, Masahiro Ohira, Miho Akabane, Kazunari Sasaki, Hideki Ohdan. Abdominal aortic calcification among gastroenterological and transplant surgery. Annals of Gastroenterological Surgery. 2024
Yuki Imaoka, Masahiro Ohira, Saki Sato, Ichiya Chogahara, Tomoaki Bekki, Kouki Imaoka, Ryosuke Nakano, Takuya Yano, Hiroshi Sakai, Shintaro Kuroda, et al. Impact of a Liver Immune Status Index among Living Liver Transplant Recipients with Hepatocellular Carcinoma. JMA journal. 2024. 7. 2. 232-239
Kouki Imaoka, Masahiro Ohira, Minoru Hattori, Ichiya Chogahara, Saki Sato, Mayuna Nakamura, Tomoaki Bekki, Koki Sato, Yuki Imaoka, Ryosuke Nakano, et al. Immunotherapy Using Activated Natural Killer Cells Improves Postoperative Neutrophil-to-Lymphocyte Ratio and Long-Term Prognosis of Living Donor Liver Transplant Recipients With Hepatocellular Carcinoma. Transplantation proceedings. 2024
Ryosuke Nakano, Ichiya Chogahara, Masahiro Ohira, Kouki Imaoka, Saki Sato, Tomoaki Bekki, Koki Sato, Yuki Imaoka, Doskali Marlen, Yuka Tanaka, et al. Atherosclerosis Deteriorates Liver Ischemia/Reperfusion Injury Via Interferon Regulatory Factor-1 Overexpression in a Murine Model. Transplantation proceedings. 2024
Tomoaki Bekki, Masahiro Ohira, Ichiya Chogahara, Kouki Imaoka, Yuki Imaoka, Ryosuke Nakano, Hiroshi Sakai, Hiroyuki Tahara, Kentaro Ide, Yuka Tanaka, et al. Association of Abdominal Aortic Calcification With the Postoperative Metabolic Syndrome Components After Liver Transplantation. Transplantation proceedings. 2024

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MISC (360)：

中野亮介, 中野亮介, 大平真裕, 今岡祐輝, 田中友加, 大段秀樹. Immunoregulatory function of donor liver dendritic cells: key to liver transplant tolerance. Organ Biology (Web). 2023. 30. 2
奥村由美子, 大平真裕, 川下遥, 樫山誠也, 小野寺一, 清水誠一, 黒田慎太郎, 田原裕之, 井手健太郎, 小林剛, et al. 臓器移植患者における新規(1→3)β-Dグルカン測定試薬の有用性の検討. 医療と検査機器・試薬. 2019. 42. 3. 232-237
大平真裕, 清水誠一, 今岡祐輝, 佐藤幸毅, 山根宏明, 秋本修志, 田口和浩, 田中飛鳥, 黒田慎太郎, 田原裕之, et al. プレシジョン・メディシンの外科学への応用臓器移植における免疫機能分子一塩基多型の役割. 日本外科学会定期学術集会抄録集. 2019. 119回. WS-25
小林剛, 井手健太郎, 大平真裕, 田原裕之, 黒田慎太郎, 橋本慎二, 浜岡道則, 大段秀樹. 大腸癌肝転移切除における肝静脈合併切除再建. 日本外科学会定期学術集会抄録集. 2019. 119回. SF-018
佐藤幸毅, 大平真裕, 今岡祐輝, 濱岡道則, 橋本慎二, 黒田慎太郎, 田原裕之, 小林剛, 井手健太郎, 田中友加, et al. 生体肝移植におけるMELD scoreによる術後難治性腹水の予測とその対策. 日本外科学会定期学術集会抄録集. 2019. 119回. SF-095

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Books (1)：

Gene Therapy and Cell Therapy Through the Liver
Springer 2015 ISBN:4431556656

Lectures and oral presentations (33)：

Liver-Resident Natural Killer Cells as Adjuvant Treatment for Hepatocellular Carcinoma Post-Liver Transplantation
(APASL 2024 2024)
肝腎同時移植と腎性貧血治療について
(長野県臓器移植推進講演会 2024)
Nationwide survey of living donor liver transplantation outcomes for hepatocellular carcinoma
(JDDW2023 2023)
臓器移植における抗体関連性拒絶の制御を目指した取り組み
(第59回日本移植学会総会 2023)
Nationwide survey of analysis of poor prognostic factors for living donor liver transplantation for hepatocellular carcinoma.
(第59回日本移植学会総会 2023)

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Professional career (1)：

博士(医学) (広島大学)

Work history (6)：

2014/04/01 - Hiroshima University Hospital Assistant Professor
2013/04/01 - 2014/03/31 Hiroshima University Institute of Biomedical & Health Sciences Assistant Professor (Special Appointment)
2012/10/01 - 2013/03/31 Hiroshima University Hospital Clinical Fellow
2011/06/01 - University of Miami Department of Surgery Research Assistant Professor
2009/09/01 - University of Miami Department of Surgery Research Associate III

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Awards (10)：

2017/10/10 - 広島県臓器移植等推進功労者に対する知事の感謝状臓器移植等推進功労者に対する知事の感謝状
2016/10/29 - Asian Transplant Society 2016 Asian Transplant Week, Best Abstract Award (Silver)
2014 - ILTS 2014 ILTS Young Investigator Award Novel adjuvant immunotherapy using liver natural killer cells for preventing recurrence of hepatocellular carcinoma in liver transplantation.
2011 - ASTS 2011 Annual Scientific Exchange Young Innovator Award
2010 - 広仁会 2010年広仁会賞

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