Rchr
J-GLOBAL ID:201801007188434994   Update date: Apr. 19, 2024

Saito Toshiro

サイトウ トシロウ | Saito Toshiro
Affiliation and department:
Job title: Professor
Research field  (1): Cardiology
Research keywords  (7): ミトコンドリア生物学 ,  mitophagy ,  autophagy ,  chronic heart failure ,  ischemic heart disease ,  vascular endothelium ,  vascular smooth muscle
Research theme for competitive and other funds  (11):
  • 2023 - 2026 心臓の虚血再灌流におけるマイトファジーに関する研究
  • 2022 - 2025 大伏在静脈グラフトに長期開存をもたらす、周囲脂肪組織の血管保護作用に関する研究
  • 2021 - 2024 血管新生因子を搭載した人工型エクソソームによる、難治性心疾患の新規治療法の開発
  • 2019 - 2023 急性心筋虚血における、ミトコンドリアのオートファジーの分子機構解明
  • 2019 - 2021 Ulk1-Rab9 経路を標的とした、虚血性心疾患に対する新規治療戦略の開発
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Papers (27):
  • Yutaro Matsuno, Masashi Yanagihara, Koji Ueno, Toshiro Saito, Hiroshi Kurazumi, Ryo Suzuki, Shunsaku Katsura, Atsunori Oga, Kimikazu Hamano. Dry preserved multilayered fibroblast cell sheets are a new manageable tool for regenerative medicine to promote wound healing. Scientific Reports. 2022. 12. 1
  • Toshiro Saito, Hiroshi Kurazumi, Ryo Suzuki, Kazumasa Matsunaga, Sarii Tsubone, Bochao Lv, Sei Kobayashi, Takashi Nagase, Takahiro Mizoguchi, Makoto Samura, et al. Perivascular Adipose Tissue Is a Major Source of Nitric Oxide in Saphenous Vein Grafts Harvested via the No-Touch Technique. Journal of the American Heart Association. 2022. 11. 3. e020637
  • Jihoon Nah, Akihiro Shirakabe, Risa Mukai, Peiyong Zhai, Eun-Ah Sung, Andreas Ivessa, Wataru Mizushima, Yasuki Nakada, Toshiro Saito, Chengchen Hu, et al. Ulk1-dependent alternative mitophagy plays a protective role during pressure overload in the heart. Cardiovascular research. 2022
  • Mingming Tong, Toshiro Saito, Peiyong Zhai, Shin-Ichi Oka, Wataru Mizushima, Michinari Nakamura, Shohei Ikeda, Akihiro Shirakabe, Junichi Sadoshima. Alternative Mitophagy Protects the Heart Against Obesity-Associated Cardiomyopathy. Circulation research. 2021. 129. 12. 1105-1121
  • Sota Yoshimine, Koji Ueno, Junichi Murakami, Toshiro Saito, Ryo Suzuki, Yoshiyuki Asai, Eiji Ikeda, Toshiki Tanaka, Kimikazu Hamano. Autologous Multilayered Fibroblast Sheets Can Reinforce Bronchial Stump in a Rat Model. Seminars in thoracic and cardiovascular surgery. 2021. 34. 1. 349-358
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MISC (20):
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Lectures and oral presentations  (35):
  • 冠動脈バイパス術の大伏在静脈グラフト採取において、No-touch法がグラフト血管の長期開存をもたらす機序に関する研究
    (第62回日本平滑筋学会総会 2020)
  • The central role of Ulk1-dependent autophagy in mediating mitophagy in the heart during ischemia and reperfusion
    (Annual Meeting of the Physiological Society of Japan 2020)
  • PRMT5-induced Arginine Methylation Mediates Energy Stress-induced Autophagy in the Heart
    (Basic cardiovascular Science Scientific Sessions 2019)
  • ULK1-dependent Mitophagy is Essential for Maintaining Cardiac Function during High Fat Diet-induced Diabetic Cardiomyopathy.
    (Experimental Biology 2019)
  • Mitophagy is Essential for Maintaining Cardiac Function During High Fat Diet-Induced Diabetic Cardiomyopathy
    (American Heart Association Scientific Sessions 2018)
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Education (2):
  • 2007 - 2011 九州大学大学院 医学系学府
  • 1998 - 2004 Kyushu University School of Medicine
Professional career (1):
  • 医学博士 (九州大学)
Work history (8):
  • 2024/04 - 現在 Hyogo Medical University Department of Physiology, Faculty of Medicine Professor
  • 2023/01 - 2024/03 Wakayama Medical University Department of Physiology Associate Professor
  • 2018/06 - 2022/12 Graduate School of Medicine, Yamaguchi University Dept of Surgery and Clinical Science Assistant Professor
  • 2013/08 - 2018/05 Rutgers University New Jersey Medical School Department of Cell Biology and Molecular Medicine
  • 2012/04 - 2013/07 Kyushu University
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Awards (12):
  • 2019/11 - 公益財団法人持田記念医学薬学振興財団 2019年度持田記念研究助成
  • 2019/10 - 公益財団法人金原一郎記念医学医療振興財団 第34回基礎医学医療研究助成
  • 2019/02 - 公益信託 循環器学研究振興基金
  • 2019/01 - 山口大学医学部 ニューフロンティアプロジェクト研究助成
  • 2018/11 - 公益財団法人MSD生命科学財団 研究助成 2018
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Association Membership(s) (7):
JAPAN SOCIETY OF SMOOTH MUSCLE RESEARCH ,  The Japanese Circulation Society ,  日本分子生物学会 ,  日本生化学会 ,  日本薬理学会 ,  American Heart Association ,  THE PHYSIOLOGICAL SOCIETY OF JAPAN
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