Research field (3):
Structural biochemistry
, Experimental pathology
, Virology
Research keywords (8):
インフルエンザ
, HIV
, エンテロウイルス
, 動物モデル
, 病原性
, 病理学
, in silico 構造解析
, ウイルス学
Research theme for competitive and other funds (1):
2021 - 2024 VP1-145変異によるEV-A71構造機能の制御ネットワークの解明
Papers (22):
Mami Matsuda, Asuka Hirai-Yuki, Osamu Kotani, Michiyo Kataoka, Xin Zheng, Daisuke Yamane, Masaru Yokoyama, Koji Ishii, Masamichi Muramatsu, Ryosuke Suzuki. Loxapine inhibits replication of hepatitis A virus in vitro and in vivo by targeting viral protein 2C. PLoS pathogens. 2024. 20. 3. e1012091
Mai Izumida, Osamu Kotani, Hideki Hayashi, Chris Smith, Tsutomu Fukuda, Koushirou Suga, Masatomo Iwao, Fumito Ishibashi, Hironori Sato, Yoshinao Kubo. Unique Mode of Antiviral Action of a Marine Alkaloid against Ebola Virus and SARS-CoV-2. Viruses. 2022. 14. 4. 816-816
Christopher Sumner, Osamu Kotani, Shuohui Liu, Karin Musier-Forsyth, Hironori Sato, Akira Ono. Molecular Determinants in tRNA D-arm Required for Inhibition of HIV-1 Gag Membrane Binding. Journal of Molecular Biology. 2022. 434. 2. 167390-167390
Osamu Kotani, Yasushi Suzuki, Shinji Saito, Akira Ainai, Akira Ueno, Takuya Hemmi, Kaori Sano, Koshiro Tabata, Masaru Yokoyama, Tadaki Suzuki, et al. Structure-Guided Creation of an Anti-HA Stalk Antibody F11 Derivative That Neutralizes Both F11-Sensitive and -Resistant Influenza A(H1N1)pdm09 Viruses. Viruses. 2021. 13. 9. 1733-1733
2011 - 2015 Nippon Veterinary and Life Science University Graduate School of Veterinary Medicine and Life Science
Professional career (1):
博士(獣医学) (日本獣医生命科学大学)
Work history (1):
2015/05 - 現在 国立感染症研究所 病原体ゲノム解析研究センター
Awards (1):
2019/10 - 第67 回日本ウイルス学会学術集会 ポスター賞 Prediction of molecular dynamics based structural models of the Pr55Gag precursor of HIV-1
Association Membership(s) (4):
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, THE JAPANESE SOCIETY FOR AIDS RESEARCH
, THE JAPANESE SOCIETY OF VETERINARY SCIENCE
, THE JAPANESE SOCIETY FOR VIROLOGY