Suehiro Jun'ichi

Affiliation and department：
Other affiliations (1)：

Research field (4)： Systems genomics , Medical biochemistry , Tumor biology , Pharmacology

Research keywords (13)： sepsis , トランスポーター , アミノ酸 , DNAマイクロアレイ , ChIP-seq , RNA-seq , 遺伝子発現解析 , がん微小環境 , 血管内皮細胞 , がん転移 , 炎症 , 腫瘍血管新生 , 血管生物学

Research theme for competitive and other funds (5)：

2014 - 2017 Functional analysis of amino acid transporter LAT1 in tumor endothelial cells
2013 - 2015 Development of in vitro vascular network model for angiogenesis research
2012 - 2014 Molecular mechanism of transcriptional regulation by NFATc in tumor endothelial cells
2010 - 2012 内皮活性化転写因子Egr-1、Egr-3の機能解析
2010 - 2011 Functional analysis of transcription factors Egr-1 and Egr-3 in VEGF activated endothelial cells

Papers (33)：

Jun-Ichi Suehiro, Toru Kimura, Toshiyuki Fukutomi, Hisamichi Naito, Yasuharu Kanki, Youichiro Wada, Yoshiaki Kubota, Nobuyuki Takakura, Hiroyuki Sakurai. Endothelial specific LAT1 ablation normalizes tumor vasculature. JCI insight. 2024
Yukinori Ikeda, Jun-ichi Suehiro, Hiroko Oshima, Sau Yee Kok, Kazuki Takahashi, Hiroyuki Sakurai, Tetsuro Watabe, Masanobu Oshima, Yukiko T. Matsunaga. Tumor-microvessel on-a-chip reveals sequential intravasation cascade of cancer cell clusters. 2024
Jean Cacheux, Aurélien Bancaud, Daniel Alcaide, Jun-ichi Suehiro, Yoshihiro Akimoto, Hiroyuki Sakurai, Yukiko T. Matsunaga. Endothelial tissue remodeling induced by intraluminal pressure enhances paracellular solute transport. 2023
Masaru Takada, Daisuke Fukuhara, Toshihiko Takiura, Yukino Nishibori, Masashi Kotani, Zentaro Kiuchi, Akihiko Kudo, Olga Beltcheva, Noriko Ito-Nitta, Kazuhiro R Nitta, et al. Involvement of GLCCI1 in mouse spermatogenesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2023. 37. 1. e22680
Yuji Sasaki, Yoshiki Higashijima, Jun-Ichi Suehiro, Takehito Sugasawa, Eri Oguri-Nakamura, Shigetomo Fukuhara, Nao Nagai, Yosuke Hirakawa, Youichiro Wada, Masaomi Nangaku, et al. Lysine demethylase 2B regulates angiogenesis via Jumonji C dependent suppression of angiogenic transcription factors. Biochemical and biophysical research communications. 2022. 605. 16-23

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MISC (9)：

山賀貴, 末弘淳一, 櫻井裕之. LAT1阻害薬JPH203への抵抗性はGCN2-ATF4経路が関与する. 日本薬理学雑誌. 2020. 155. Supplement
神吉康晴, 東島佳毅, 東島佳毅, 末弘淳一, 油谷浩幸, 南敬. 血管新生をコントロールするエピゲノム修飾タンパク質複合体. 日本心血管内分泌代謝学会学術総会プログラム及び抄録集. 2019. 23rd
末弘淳一. LAT1を介した内皮活性化機序の解明. 上原記念生命科学財団研究報告集(CD-ROM). 2018. 32
R. Usuba, J. Pauty, H. Takahashi, K. Fujisawa, J. Suehiro, K. Yano, T. Nishizawa, Y. T. Matsunaga. Engineering In Vitro Microvasculature for Drug-Responsive Permeability Assay. TISSUE ENGINEERING PART A. 2016. 22. S64-S64
末弘淳一, 南敬. 血管内皮細胞において転写因子NFATc依存に誘導されるCXCR7ケモカイン受容体は,SDF-1を介した血管新生に必須である. がん研究分野の特性等を踏まえた支援活動公開シンポジウムプログラム・抄録集平成24年度. 2013. 54

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Patents (2)：

Professional career (1)：

Work history (2)：

2013/04 - 現在 Kyorin University Faculty of Medicine
2009/04 - 2013/03 The University of Tokyo Research Center for Advanced Science and Technology

Association Membership(s) (4)：

THE JAPANESE PHARMACOLOGICAL SOCIETY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE CANCER ASSOCIATION , 日本血管生物医学会

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