Rchr
J-GLOBAL ID：201801007705627765
Update date: Jun. 18, 2024
IKUSHIMA Yoshiko Matsumoto
イクシマ ヨシコ | IKUSHIMA Yoshiko Matsumoto
Affiliation and department：
Job title：
Sponsored Researcher
Research theme for competitive and other funds (5)：
- 2019 - 2022 膵β細胞の量・機能を制御する細胞内シグナルの同定
- 2016 - 2019 Role of MEK/ERK signaling in pancreatic beta cells - to develop a novel treatment strategy for type 2 diaetes
- 2013 - 2015 Analyses of hematopoietic stem cell division patterns in biomimetic culture conditions and optimization of culture condition for hematopoietic stem cells
- 2010 - 2015 Analysis of Niche Regulation for Cancer Stem Cells
- 2011 - 2012 単一細胞レベルでの造血幹細胞の対称・非対称分裂の制御機構の解明
Papers (11)：
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Maya Matsushita, Motoharu Awazawa, Naoki Kobayashi, Yoshiko M Ikushima, Kotaro Soeda, Miwa Tamura-Nakano, Masafumi Muratani, Kenta Kobayashi, Matthias Blüher, Jens C. Brüning, et al. An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance. Cell Chemical Biology. 2022. 29. 4. 680-689.e6
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Yoshiko M Ikushima, Motoharu Awazawa, Naoki Kobayashi, Sho Osonoi, Seiichi Takemiya, Hiroshi Kobayashi, Hirotsugu Suwanai, Yuichi Morimoto, Kotaro Soeda, Jun Adachi, et al. MEK/ERK Signaling in β-Cells Bifunctionally Regulates β-Cell Mass and Glucose-Stimulated Insulin Secretion Response to Maintain Glucose Homeostasis. Diabetes. 2021. 70. 7. 1519-1535
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Fumio Arai*, Patrick S Stumpf*, Yoshiko M Ikushima*, Kentaro Hosokawa, Aline Roch, Matthias P Lutolf, Toshio Suda, Ben D MacArthur. Machine Learning of Hematopoietic Stem Cell Divisions from Paired Daughter Cell Expression Profiles Reveals Effects of Aging on Self-Renewal. Cell systems. 2020. 11. 6. 640-652
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Kentaro Hosokawa, Ben D. MacArthur, Yoshiko M Ikushima, Hirofumi Toyama, Yoshikazu Masuhiro, Shigemasa Hanazawa, Toshio Suda, Fumio Arai. The telomere binding protein Pot1 maintains haematopoietic stem cell activity with age. NATURE COMMUNICATIONS. 2017. 8. 1. 804
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Masayuki Yamashita, Eriko Nitta, Go Nagamatsu, Yoshiko M Ikushima, Kentaro Hosokawa, Fumio Arai, Toshio Suda. Nucleostemin is indispensable for the maintenance and genetic stability of hematopoietic stem cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2013. 441. 1. 196-201
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MISC (2)：
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生島 芳子, 粟澤 元晴, 小林 直樹, 遅野井 祥, 諏訪内 浩紹, 守本 祐一, 添田 光太郎, 足立 淳, 村谷 匡史, 水上 浩哉, et al. 膵ホルモンの分泌シグナル-生理と病態 インスリン抵抗性状態での膵β細胞におけるMEK/ERKシグナル伝達の役割(Roles of MEK/ERK signaling in pancreatic β cells under insulin resistant status). 糖尿病. 2021. 64. Suppl.1. S6-6
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生島 芳子, 粟澤 元晴, 小林 直樹, 遅野井 祥, 諏訪内 浩紹, 守本 祐一, 添田 光太郎, 足立 淳, 村谷 匡史, 水上 浩哉, et al. 膵ホルモンの分泌シグナル-生理と病態 インスリン抵抗性状態での膵β細胞におけるMEK/ERKシグナル伝達の役割(Roles of MEK/ERK signaling in pancreatic β cells under insulin resistant status). 糖尿病. 2021. 64. Suppl.1. S6
Lectures and oral presentations (2)：
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Roles of MEK/ERK signaling in pancreatic β cells under insulin resistant status
(The 64th Annual Meeting of Japanese Diabetes Society 2021)
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膵β細胞制御におけるMek/Erkシグナルの役割の解明
(第62回日本糖尿病学会年次学術集会 2019)
Education (2)：
- 2009 - 2013 Keio University
- 2003 - 2009 The University of Tokyo Faculty of Medicine School of Medicine
Professional career (2)：
- 医学博士 (慶應義塾大学)
- 学士 (医学) (The University of Tokyo)
Work history (4)：
- 2021 - 現在 The University of Edinburgh University BHF Centre for Cardiovascular Science Sponsored Researcher
- 2015 - 2021 国立国際医療研究センター研究所 糖尿病センター 分子糖尿病医学研究部 上級研究員
- 2013 - 2015 Keio University School of Medicine
- 2011 - 2013 日本学術振興会 特別研究員 (DC2)
Awards (4)：
- 2019 - 第62回日本糖尿病学会 若手研究奨励賞
- 2019 - 第33回日本糖尿病肥満動物学会 若手研究奨励賞
- 2012 - 10th Annual Meeting of International Society for Stem Cell Research (ISSCR) Junior Investigator Poster Awards
- 2012 - 第74回日本血液学会 奨励賞
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