Research field (3):
Functional biochemistry
, Food sciences
, Pharmaceuticals - chemistry and drug development
Research keywords (4):
8-Nitro-cGMP
, 質量分析装置
, メタボローム解析
, 活性イオウ分子種
Research theme for competitive and other funds (12):
2023 - 2026 超硫黄分子の代謝制御メカニズムの解明
2020 - 2023 Reaction mechanism of a novel cysteine persulfide synthase and its function
2018 - 2020 Novel reactive persulfide-producing system in bacteria and its involvement in bacterial pathogenicity
2017 - 2019 Production of polysulfidated protein and regulation mechanism of its structure/functions
2014 - 2018 Polysulfur metabolome and regulation of anti-oxidative stress responses
2016 - 2017 Study of the mechanism of biosynthesis of polysulfurated proteins coupled with translation
2015 - 2017 Novel oxidative stress response mechanism by reactive sulfur species and 8-nitro-cGMP
2014 - 2016 Novel signaling pathway of bacterial stress responses and host defense via autophagy
2013 - 2015 Mechanism of intracellular formation of cysteine polysulfide and reactive oxygen species signaling
2014 - 2015 Regulatory mechanisms of protein S-polythiolation
2014 - 2015 Analysis of intarocular antioxidant and development of intraocular irrigating solution
2013 - 2014 Clarification of the endogenous formation of the novel cyclic nucleotide 8-SH-cGMP and its signaling function
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Papers (80):
Tomas Majtan, Thomas Olsen, Jitka Sokolova, Jakub Krijt, Michaela Křížková, Tomoaki Ida, Tamás Ditrói, Hana Hansikova, Ondrej Vit, Jiri Petrak, et al. Deciphering pathophysiological mechanisms underlying cystathionine beta-synthase-deficient homocystinuria using targeted metabolomics, liver proteomics, sphingolipidomics and analysis of mitochondrial function. Redox biology. 2024. 73. 103222-103222
Akira Nishimura, Sunghyeon Yoon, Tetsuro Matsunaga, Tomoaki Ida, Minkyung Jung, Seiryo Ogata, Masanobu Morita, Jun Yoshitake, Yuka Unno, Uladzimir Barayeu, et al. Longevity control by supersulfide-mediated mitochondrial respiration and regulation of protein quality. Redox biology. 2024. 69. 103018-103018
Shingo Kasamatsu, Ayaka Kinno, Chiharu Miura, Jun-Ichi Hishiyama, Kensuke Fukui, Shoji Kure, Kazunobu Tsumura, Tomoaki Ida, Tetsuro Matsunaga, Takaaki Akaike, et al. Quantitative profiling of supersulfides naturally occurring in dietary meats and beans. Analytical biochemistry. 2023. 685. 115392-115392
Shingo Kasamatsu, Takuma Owaki, Somei Komae, Ayaka Kinno, Tomoaki Ida, Takaaki Akaike, Hideshi Ihara. Untargeted polysulfide omics analysis of alternations in polysulfide production during the germination of broccoli sprouts. Redox Biology. 2023. 102875-102875