Rchr
J-GLOBAL ID：201801007789887554   Update date: Oct. 22, 2024

Shibata Yasuaki

シバタ ヤスアキ | Shibata Yasuaki
Research field  (1)： Anatomy
Research keywords  (2)： Involvement of Wnt/β-catenin and c-Myc signal in development and progression of HCC ,  Epigenetics in development and progression of HCC
Research theme for competitive and other funds  (32)：
  • 2024 - 2025 The involvement of dimethylation of histone H3K36 induced by DDR in the development and progression of human liver disease
  • 2023 - 2024 Wnt/β-catenin signal modulates DDR and EMT by dimethylation of histone H3K36 through NSD2 in hepatocellular carcinoma
  • 2020 - 2023 Structure and function of spermatocyte nucleolus in the meiotic prophase; electron microscopic and molecular anatomical analysis
  • 2018 - 2022 Molecular targeted therapy for MRONJ
  • 2018 - 2021 Novel pathophysiology underlying cardiac conduction defect due to mutations of gap junction genes
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Papers (79)：
  • Naoya Murayama, Takafumi Miyaki, Daisuke Okuzaki, Yasuaki Shibata, Takehiko Koji, Asuka Inoue, Junken Aoki, Hideki Hayashi, Yoshimasa Tanaka, Hiroyuki Murota. Transcriptome profiling of anhidrotic eccrine sweat glands reveals that olfactory receptors on eccrine sweat glands regulate perspiration in a ligand-dependent manner. JID Innovations. 2023. 3. 4. 100196-100196
  • Narantsog Choijookhuu, Yasuaki Shibata, Takumi Ishizuka, Yan Xu, Takehiko Koji, Yoshitaka Hishikawa. An Advanced Detection System for In Situ Hybridization Using a Fluorescence Resonance Energy Transfer-based Molecular Beacon Probe. Acta Histochemica et Cytochemica. 2022. 55. 5. 119-128
  • Naoko Hattori, Takeya Nakagawa, Mitsuhiro Yoneda, Hiromi Hayashida, Kaori Nakagawa, Kazuo Yamamoto, Myo Win Htun, Yasuaki Shibata, Takehiko Koji, Takashi Ito. Compounds in cigarette smoke induce EGR1 expression via the AHR, resulting in apoptosis and COPD. Journal of biochemistry. 2022
  • Shinichirou Ito, Norio Kasahara, Kei Kitamura, Satoru Matsunaga, Toshihide Mizoguchi, Myo Win Htun, Yasuaki Shibata, Shinichi Abe, Masayuki Takano, Akira Yamaguchi. Pathological differences in the bone healing processes between tooth extraction socket and femoral fracture. Bone Reports. 2022. 16. 101522-101522
  • Myo Win Htun, Yasuaki Shibata, Kyaw Soe, Takehiko Koji. Nuclear Expression of Pygo2 Correlates with Poorly Differentiated State Involving c-Myc, PCNA and Bcl9 in Myanmar Hepatocellular Carcinoma. ACTA HISTOCHEMICA ET CYTOCHEMICA. 2021. 54. 6. 195-206
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MISC (48)：
  • 菱川善隆, CHOIJOOKHUU Narantsog, 石塚匠, 柴田恭明, 小路武彦. In situ hybridization法. 組織細胞化学. 2023. 2023
  • 石塚匠, Choijookhuu Narantsog, 柴田恭明, 小路武彦, 菱川善隆. A Highly Sensitive Detection System for in situ Hybridization Using Fluorescence Resonance Energy Transfer (FRET) Phenomenon. 顕微鏡. 2023. 58. 3
  • 菱川善隆, CHOIJOOKHUU Narantsog, 石塚匠, 柴田恭明, 小路武彦. in situ hybridizationがひらく形態科学の将来像. 日本皮膚科学会雑誌. 2022. 132. 5
  • 菱川善隆, CHOIJOOKHUU Narantsog, 石塚匠, 柴田恭明, 小路武彦. FISH・ISH. 病理と臨床. 2022. 40
  • 菱川善隆, CHOIJOOKHUU Narantsog, 石塚匠, 柴田恭明, 小路武彦, 小路武彦. In situ hybridization法. 組織細胞化学. 2022. 2022
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Books (12)：
  • 酵素免疫組織化学染色を科学する
    Medical Technology、医歯薬出版株式会社 2024
  • In situ hybridization 法 組織細胞化学 2024
    組織細胞化学会(編)、中西印刷 2024
  • In situ hybridization 法 組織細胞化学 2023
    組織細胞化学会(編)、中西印刷 2023
  • In situ hybridization 法 組織細胞化学 2022
    組織細胞化学会(編)、中西印刷 2022
  • 1. がんの分子病理学 B. 解析法 1. FISH・ISH
    病理と臨床 vol. 40 文光堂 2022
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Lectures and oral presentations  (35)：
  • 肝細胞がんに於けるNSD2発現及びヒストンH3リジン36ジメチル化の上昇
    (第129回日本解剖学会総会・全国学術集会 2024)
  • Myanmar 人肝細胞がんに於けるWnt/β-cate補助因子Pygo2とc-Myc の相関発現
    (第128回日本解剖学会総会・全国学術集会 2023)
  • ミャンマー人肝細胞がんに於けるWnt/β-cateninシグナル補助因子と c-Mycの発現相関。
    (第54回日本臨床分子形態学会総会・学術集会 2022)
  • Myanmar人肝細胞がんに於けるPygo2 高発現とBcl9, c-Mye, PCNAの相関発現。
    (第63回日本組織細胞化学会総会・学術集会 2022)
  • ミャンマー人肝細胞がん分化型低下に伴うPygo2及びc-Myc の相関的な発現上昇
    (第127回日本解剖学会総会・全国学術集会 2022)
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Education (2)：
  • 1989 - 1993 長崎大学大学院 歯学研究科
  • 1982 - 1989 Nagasaki University School of Dentistry
Professional career (1)：
  • 歯学博士 (長崎大学)
Work history (2)：
  • 2019/04 - 現在 Nagasaki University Graduate School of Biomedical Scieneces Histochemistry and Cell Biology Associate professor
  • 2016/03 - 2019/03 Nagasaki University Graduate School of Biomedical Scieneces Histochemistry and Cell Biology Senior assistant professor
Committee career (3)：
  • 2022/04 - 現在 日本組織細胞化学会 編集委員(Acta Histochm Cytochem)
  • 2018/04 - 現在 The Japanese Society for Clinical Molecular Morphology Representative
  • 2018/04 - 現在 Japanese Society of Histochemistry and Cytochemistry Representative
Awards (1)：
  • 2003 - 日本骨形態計測学会 日本骨形態計測学会学会賞 骨再生過程における遺伝子発現の網羅的解析
Association Membership(s) (4)：
日本顕微鏡学会 ,  THE JAPANESE SOCIETY FOR CLINICAL MOLECULAR MORPHOLOGY ,  JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY ,  THE JAPANESE ASSOCIATION OF ANATOMISTS
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