KONO MICHIHITO

Affiliation and department：

Research field (1)： Allergies and connective tissue disease

Research theme for competitive and other funds (5)：

2023 - 2026 ミクログリアに注目した抗リン脂質抗体による中枢神経障害の病態解明
2022 - 2025 マルチオミクス解析を用いた細胞間相互作用に注目した精神神経ループスの病態解明
2021 - 2023 ミクログリアに注目した精神神経ループスの病態解明
2020 - 2023 T細胞細胞内代謝に注目した全身性エリテマトーデスの病態解明
2019 - 2021 Molecular mechanisms of neuropsychiatric lupus pathogenesis and development of novel therapies

Papers (99)：

Jiang Wei, Yuichiro Fujieda, Yusuke Fujita, Yusuke Ogata, Ryo Hisada, Michihito Kono, Olga Amengual, Masaru Kato, Tatsuya Atsumi. Phosphatidylserine-Dependent Anti-prothrombin Antibodies as a Key Predictor for Systemic Lupus Erythematosus in Patients with Primary Antiphospholipid Syndrome: A retrospective longitudinal cohort study. Modern rheumatology. 2024
Shuhei Takeyama, Michihito Kono, Kuniyuki Aso, Kazuro Kamada, Maria Tada, Masato Tarumi, Yui Kosumi, Masaru Yoshimura, Keita Ninagawa, Ryo Hisada, et al. Relation between hydroxychloroquine dose and continuation rate in patients with systemic lupus erythematosus. Modern rheumatology. 2024
Ryo Hisada, Michihito Kono. Potential therapies targeting metabolic pathways in systemic lupus erythematosus. Clinical immunology (Orlando, Fla.). 2024. 263. 110224-110224
Maria Tada, Yuki Kudo, Michihito Kono, Masatoshi Kanda, Shuhei Takeyama, Kodai Sakiyama, Hotaka Ishizu, Tomohiro Shimizu, Tsutomu Endo, Ryo Hisada, et al. Itaconate reduces proliferation and migration of fibroblast-like synoviocytes and ameliorates arthritis models. Clinical immunology (Orlando, Fla.). 2024. 264. 110255-110255
Risako Koga, Takashi Maehara, Ryuichi Aoyagi, Ryusuke Munemura, Yuka Murakami, Atsushi Doi, Michihito Kono, Hidetaka Yamamoto, Hiroaki Niiro, Tamotsu Kiyoshima, et al. Granzyme K- and amphiregulin-expressing cytotoxic T cells and activated extrafollicular B cells are potential drivers of IgG4-related disease. The Journal of allergy and clinical immunology. 2023. 153. 4. 1095-1112

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MISC (124)：

Masayuki Mizui, Michihito Kono. Novel therapeutic strategies targeting abnormal T-cell signaling in systemic lupus erythematosus. Clinical Immunology. 2024. 262. 110182-110182
崎山広大, 阿部靖矢, 藤枝雄一郎, 多田麻里亜, 守谷悠, 安田充孝, 久田諒, 河野通仁, 加藤将, AMENGUAL Olga, et al. Functional MRIによる動的機能連関解析を用いた炎症性関節炎患者における治療効果予測. 日本臨床リウマチ学会プログラム・抄録集. 2022. 37th
吉村大, 河野通仁, 阿部靖矢, 久田諒, 藤枝雄一郎, 加藤将, アメングアルオルガ, 大庭幸治, 渥美達也. 関節リウマチ患者のニューモシスチス肺炎に対するサラゾスルファピリジンの一次予防効果. 日本臨床リウマチ学会プログラム・抄録集. 2022. 37th
KUDO Yuki, KATO Masaru, SHIBATA Yuhei, KONO Michihito, FUJIEDA Yuichiro, AMENGUAL Olga, ATSUMI Tatsuya. Establishment of systemic sclerosis associated pulmonary arterial hypertension specific endothelial cells through iPSCs and their functionl and molecular analyses. 日本リウマチ学会総会・学術集会プログラム・抄録集. 2022. 66th
TADA Maria, KATO Masaru, SAKIYAMA Kodai, TSUCHIDA Naohisa, NISHINO Kokoro, MORIYA Haruka, YASUDA Mitsutaka, NINAGAWA Keita, KONO Michihito, FUJIEDA Yuichiro, et al. Krebs von den Lunge-6 as a quantitative biomarker for the extent of systemic sclerosis associated interstitial lung disease. 日本リウマチ学会総会・学術集会プログラム・抄録集. 2022. 66th

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Professional career (1)：

博士(医学) (北海道大学)

Work history (1)：

2022/04 - 現在北海道大学病院リウマチ・腎臓内科助教

Awards (6)：

2020/12 - 日本免疫学会日本免疫学会研究奨励賞
2020/06 - 公益財団法人日本リウマチ財団塩川美奈子・膠原病研究奨励賞
2020/03 - 北海道大学大学院医学研究院第39回高桑榮松奨学基金奨励賞
2019/04 - 日本リウマチ学会奨励賞
2019/04 - 日本リウマチ学会 JCR 2019 Excellent Abstract Award

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Association Membership(s) (5)：

日本炎症・再生学会 , THE JAPAN SOCIETY FOR CLINICAL IMMUNOLOGY , THE JAPANESE SOCIETY FOR IMMUNOLOGY , JAPAN COLLEGE OF RHEUMATOLOGY , THE JAPANESE SOCIETY OF INTERNAL MEDICINE

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