Naoko Kakusho

Research theme for competitive and other funds (2)：

2011 - 2015 Studies on the functions and structures of Cdc7 kinase, essential for initiation of DNA replication
2011 - 2012 Stabilization of stalled replication forks by fork-binding proteins

Papers (19)：

Hisao Masai, Yutaka Kanoh, Naoko Kakusho, Rino Fukatsu. Detection of cellular G-quadruplex by using a loop structure as a structural determinant. Biochemical and biophysical research communications. 2020. 531. 1. 75-83
Hisao Masai, Rino Fukatsu, Naoko Kakusho, Yutaka Kanoh, Kenji Moriyama, Yue Ma, Keisuke Iida, Kazuo Nagasawa. Rif1 promotes association of G-quadruplex (G4) by its specific G4 binding and oligomerization activities. Scientific reports. 2019. 9. 1. 8618-8618
Shunsuke Kobayashi, Rino Fukatsu, Yutaka Kanoh, Naoko Kakusho, Seiji Matsumoto, Shigeru Chaen, Hisao Masai. Both a Unique Motif at the C Terminus and an N-Terminal HEAT Repeat Contribute to G-Quadruplex Binding and Origin Regulation by the Rif1 Protein. Molecular and cellular biology. 2019. 39. 4
Masai H, Kakusho N, Fukatsu R, Ma Y, Iida K, Kanoh Y, Nagasawa K. Molecular architecture of G-quadruplex structures generated on duplex Rif1 binding sequences. The Journal of biological chemistry. 2018. 293. 44. 17033-17049
Matsumoto, S, Kanoh, Y, Shimmoto, M, Hayano, M, Ueda, K, Fukatsu, R, Kakusho, N, Masai, H. Checkpoint-independent Regulation of Origin Firing by Mrc1 through Interaction with Hsk1 kinase. Mol. Cell. Biol. 2018. 39. 4

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MISC (31)：

正井久雄, 井口智弘, 伊藤さゆり, 加納豊, 覺正直子, 深津理乃, 森山賢治, 笹沼博之. 核酸-タンパク質-リン脂質相互作用を介した染色体高次構造の形成制御. 日本生化学会大会(Web). 2022. 95th
正井久雄, 井口智弘, 伊藤さゆり, 森山賢治, 覺正直子, 加納豊, 高沢佳芳, 田中卓, 鷺朋子, 深津理乃, et al. 染色体の多様な機能を支えるタンパク質高次複合体特殊な高次構造を持つタンパク質、脂質、DNAの凝集が関与するクロマチン制御(Chromatin regulation that involves assembly of protein, lipid and DNA with a special higher-order structure). 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [2S12a-07]
正井久雄, 井口智弘, 伊藤さゆり, 森山賢治, 覺正直子, 加納豊, 高沢佳芳, 田中卓, 鷺朋子, 深津理乃, et al. 染色体の多様な機能を支えるタンパク質高次複合体特殊な高次構造を持つタンパク質、脂質、DNAの凝集が関与するクロマチン制御(Chromatin regulation that involves assembly of protein, lipid and DNA with a special higher-order structure). 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [2S12a-07]
IGUCHI Tomohiro, ITO Sayuri, KAKUSHO Naoko, YAMAZAKI Satoshi, OJI Asami, FUKATSU Rino, HIRATANI Ichiro, SASANUMA Hiroyuki, MASAI Hisao. Association of Rif1 with nuclear membrane is essential for genome-wide replication timing regulation. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
ITO Sayuri, FUKATSU Rino, KAKUSHO Naoko, IGUCHI Tomohiro, MASAI Hisao. Liquid-liquid phase separation of human Rif1-derived polypepitide. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th

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