Rchr
J-GLOBAL ID：201801007994242574
Update date: Jul. 09, 2024
Sei Yonezawa
ヨネザワ セイ | Sei Yonezawa
Affiliation and department：
Job title：
講師
Research field (1)：
Pharmaceuticals - chemistry and drug development
Research keywords (6)：
核内受容体
, 腎疾患
, Cancer
, Lipid metabolism
, Diabetes
, DDS
Research theme for competitive and other funds (5)：
- 2022 - 2025 抗原提示細胞を標的としたmRNA/LNP製剤の開発と個別化がん免疫療法への応用
- 2021 - 2025 電荷反転型LNP製剤の精密設計と核酸・ペプチド医薬品開発への応用
- 2019 - 2020 尿細管間質領域特異的な薬物送達による脂質代謝調節に基づいた新規腎疾患治療戦略の確立
- 2013 - 2015 Construction of novel liposome with directional quality to kidney tubule and tubulointerstitial region to control the development of diabetic nephropathy
- 2011 - 2012 Basis examination aimed at establishing a novel therapeutics that target the accumulated lipid in diseased kidney
Papers (29)：
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Katsuki Matayoshi, Furan Song, Hiroyuki Koide, Sei Yonezawa, Chiori Nitta, Masako Okada, Nahoko Ozaki, Makiko Kurata, Tomohiro Asai. Delivery of small interfering ribonucleic acid using lipid nanoparticles prepared with pH-responsive dipeptide-conjugated lipids. Biochemical and Biophysical Research Communications. 2024. 150372-150372
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Sei Yonezawa, Yasushi Kawasaki, Yasuhiro Natori, Akinori Sugiyama. Improvement of LXR-mediated lipid metabolism in nephrotic model kidney accompanied by suppression of inflammation and fibrosis. Biochemical and Biophysical Research Communications. 2023. 666. 122-127
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Masahiro Hashimoto, Sei Yonezawa, Song Furan, Chiori Nitta, Noriyuki Maeda, Koji Tomita, Ayano Yokouchi, Hiroyuki Koide, Tomohiro Asai. Increasing the siRNA knockdown efficiency of lipid nanoparticles by morphological transformation with the use of dihydrosphingomyelin as a helper lipid. Biomaterials science. 2023. 11. 9. 3269-3277
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Hiroyuki Koide, Kazuhiro Saito, Keiichi Yoshimatsu, Beverly Chou, Yu Hoshino, Sei Yonezawa, Naoto Oku, Tomohiro Asai, Kenneth J Shea. Cooling-induced, localized release of cytotoxic peptides from engineered polymer nanoparticles in living mice for cancer therapy. Journal of controlled release : official journal of the Controlled Release Society. 2023. 355. 745-759
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Hiroyuki Koide, Hiroki Ochiai, Hikaru Suzuki, Shinya Hirata, Midori Watanabe, Sei Yonezawa, Takehisa Dewa, Naoto Oku, Tomohiro Asai. Easy preparation of a liposome-mediated protein delivery system by freeze-thawing a liposome-protein complex. Journal of materials chemistry. B. 2022. 10. 35. 6768-6776
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MISC (65)：
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宮嵜拓海, 米澤正, 室谷千佳, 浅井知浩. 腎疾患に対するリポソーム製剤の有用性. 第31回DDSカンファランス. 2023
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又吉 克樹,髙橋沙也加, 龍聡平,米澤正, 尾﨑奈穂子,田中陽平,浅井知浩. pH応答性ジペプチド脂質を含有するmRNA/LNP製剤の開発. 日本核酸医薬学会. 2023
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渡邊翠, 小出裕之, 平田真也, 米澤正, 出羽毅久, 奥直人, 奥直人, 浅井知浩. Development of protein delivery strategy using multi-functionalized liposomes. 日本薬剤学会年会講演要旨集(CD-ROM). 2023. 38th
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米澤正,浅井知浩. 腎への薬物送達と腎疾患治療を目指して. 第30回DDSカンファランス. 2022
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小出 裕之, 米澤 正, 出羽 毅久, 奥 直人, 浅井 知浩. 社会のアンメットニーズに応えるDDS 凍結融解技術を駆使した核酸・タンパク質送達方法の開発. 日本DDS学会学術集会プログラム予稿集. 2022. 38回. 74-74
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Books (2)：
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Angiogenesis assays : a critical appraisal of current techniques
J. Wiley & Sons 2006 ISBN:9780470016008
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ナノDDS製剤研究におけるバイオイメージング
Education (3)：
- 2004 - 2007 University of Shizuoka Graduate School of Pharmaceutical Sciences
- 2002 - 2004 University of Shizuoka Graduate School of Pharmaceutical Sciences
- 1998 - 2002 University of Shizuoka School of Pharmaceutical Sciences Division of Medicinal Science
Professional career (1)：
Work history (4)：
- 2019/01 - 現在 University of Shizuoka School of Pharmaceutical Sciences
- 2009/04 - 2018/12 Iwate Medical University School of Pharmacy Assistant Professor
- 2008/04 - 2009/03 Iwate Medical University School of Pharmacy
- 2007/04 - 2008/03 National Center for Global Health and Medicine
Awards (1)：
- 2003/07 - Controlled Release Society Travel Award Intracellular distribution dynamics of cationic lipid-mediated double-stranded RNA in cells by using confocal laser scan microscopy.
Association Membership(s) (4)：
日本腎臓学会
, 日本薬剤学会
, 日本脂質生化学会
, 日本薬学会
