Rchr
J-GLOBAL ID：201801008003285625
Update date: Jul. 20, 2024
HusseinHassan Aly
アリ フセインハッサン | HusseinHassan Aly
Affiliation and department：
Job title：
主任研究官
Research field (1)：
Virology
Research keywords (5)：
Cytokines
, Hepatitis
, RNA Biology and Viral Infection
, Innate Immunity
, Virology
Research theme for competitive and other funds (4)：
- 2023 - 2026 Elucidation of kinesin-transport substrate interaction specificity and novel approaches to inhibit viral infection.
- 2022 - 2025 レポーターHBVを駆使したB型肝炎ウイルス増殖機構の解析と創薬ターゲットの探索・同定に資する研究
- 2022 - 2025 B型肝炎モデル動物を用いたHBV持続感染根治治療の開発
- 2022 - 2025 HBV cccDNAの産生と維持に関わるウイルスおよび宿主因子の探索
Papers (35)：
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Asako Murayama, Hitomi Igarashi, Norie Yamada, Hussein Hassan Aly, Natalia Molchanova, Jennifer S Lin, Hironori Nishitsuji, Kunitada Shimotohno, Masamichi Muramatsu, Annelise E Barron, et al. Antiviral effect of peptoids on hepatitis B virus infection in cell culture. Antiviral research. 2024. 223. 105821-105821
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Ashraf Elbahrawy, Hassan Atalla, Abdulla A. Mahmoud, Ahmed Eliwa, Alaa Alsawak, Mohamed Alboraie, Ali Madian, Ahmed Alashker, Sadek Mostafa, Ahmed Alwassief, et al. Prediction and surveillance of de novo HCC in patients with compensated advanced chronic liver disease after hepatitis C virus eradication with direct antiviral agents. Frontiers in Virology. 2023. 3
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Adi Ariffianto, Lin Deng, Takayuki Abe, Chieko Matsui, Masahiko Ito, Akihide Ryo, Hussein Hassan Aly, Koichi Watashi, Tetsuro Suzuki, Masashi Mizokami, et al. Oxidative stress sensor Keap1 recognizes HBx protein to activate the Nrf2/ARE signaling pathway, thereby inhibiting hepatitis B virus replication. Journal of virology. 2023. 97. 10. e0128723
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Ashraf Elbahrawy, Hassan Atalla, Mohamed Alboraie, Ahmed Alwassief, Ali Madian, Mohammed El Fayoumie, Ashraf A. Tabll, Hussein H. Aly. Recent Advances in Protective Vaccines against Hepatitis Viruses: A Narrative Review. Viruses. 2023. 15. 1. 214-214
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Ayaka Washizaki, Asako Murayama, Megumi Murata, Tomoko Kiyohara, Keigo Yato, Norie Yamada, Hussein Hassan Aly, Tomohisa Tanaka, Kohji Moriishi, Hironori Nishitsuji, et al. Neutralization of hepatitis B virus with vaccine-escape mutations by hepatitis B vaccine with large-HBs antigen. Nature Communications. 2022. 13. 1. 5207-5207
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MISC (11)：
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Noriyuki Watanabe, Tomoko Date, Hussein H. Aly, Hideki Aizaki, Takaji Wakita. Induction of neutralization E2 antibody by immunization of recombinant E2 proteins. HEPATOLOGY. 2017. 66. 466A-466A
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Noriyuki Watanabe, Nanako Aihara, Tomoko Date, Hussein Hassan Aly, Hideki Aizaki, Takaji Wakita. Induction of neutralization E2 antibody by immunization of recombinant E2 proteins. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2016. 31. 380-381
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中井 正人, 伊藤 淳, 常松 聖司, 佐藤 史幸, 佃 曜子, 寺下 勝巳, 荘 拓也, 須田 剛生, 夏井坂 光輝, 小川 浩司, et al. ヒト初代B細胞におけるHCVcc感染. 日本消化器病学会雑誌. 2015. 112. 臨増総会. A354-A354
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Yuichi Abe, Hussein H. Aly, Takaji Wakita, Kunitada Shimotohno, Makoto Hijikata. Identification of signal pathway involved in infectious Hepatitis C virus (HCV) particle production. The 6th International symposium of institute network. Tokyo, Japan. 2011
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Yue Qi, Hussein H. Aly, Chieko Tsutsui, Takashi Fujita, Makoto Hijikata. IRF7 dependent IFN-alpha response in the early phase of the viral infected hepatocytes. 17th International symposium on hepatitis Cvirusand related viruses. Yokohama, Japan. 2010
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Patents (1)：
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METHOD FOR PRODUCING EPITHELIAL STEM CELLS
Lectures and oral presentations (24)：
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Development of anti-hepatitis B virus drugs, novel trends and possibilities
(Antimicrobials: Novel trends and challenges, Seminar, Gastroenterology, Azhar University, Egypt 2023)
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New advances in Hepatitis B virus treatment, a link between research and drug development
(The 30th International Conference of the Egyptian Society for Medical Microbiology (ESMM) in Association with the American Society for Microbiology (ASM) 2023)
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DHX35, RNA Helicase Inhibits Hepatitis B Virus Replication by Targeting Pregenomic RNA. Oral presentation
(The 70th Annual Meeting of the Japanese Society for Virology 2023)
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DHX35 targets pgRNA for HBV restriction
(2023 international HBV meeting 2023)
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THE IDENTIFICATION OF NEW HOST FACTORS REGULATING THE LIFE CYCLE OF HEPATITIS B VIRUS
(Global Hepatitis Summit 2023)
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Education (3)：
- 2003 - 2007 Kyoto University Institute for virus research PhD in medical science
- 1997 - 1999 Cairo University Tropical Medicine Master Degree in Tropical Medicine
- 1988 - 1995 Cairo University Medical School MD
Professional career (2)：
- PhD (Kyoto University)
- MD (Cairo University)
Work history (4)：
- 2012/03 - 現在 National Institute of Infectious Diseases Virology 2 department Senior Research Scientist
- 2010/04 - 2012/02 Hokkaido University Microbiology and Immunology Assistant Professor
- 2007/04 - 2010/03 Kyoto University Institute for Virus Research Post Doc
- 1997/09 - 2003/03 National Hepatology and Tropical Medicine Research Institute Internal Medicine Resident
Committee career (4)：
- 2021/03 - 現在 American Society for Microbiology
- 2019/09 - 現在 The American Society for Virology
- 2017/09 - 現在 The Egyptian Society for Virology
- 2009/04 - 現在 The Japanese Society for Virology
Awards (3)：
- 2014 - Japanese Society for Viral Hepatitis Liver Forum in Kyoto Award
- 2011 - Japanese society for promotion of Science (JSPS) Post-Doctoral Scholarship
- 2004 - Japanese Ministry of Education, Culture, Sports, Science and Technology, Gakushu Shoreihi scholarship
Association Membership(s) (3)：
THE RNA SOCIETY OF JAPAN
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, THE JAPANESE SOCIETY FOR VIROLOGY
