Rchr
J-GLOBAL ID：201801008054519906   Update date: May. 17, 2024

Momoka Yamaguchi

ヤマグチ モモカ | Momoka Yamaguchi
Affiliation and department：
University of Shizuoka School of Pharmaceutical Sciences

About University of Shizuoka School of Pharmaceutical Sciences


Research field  (1)： Pharmacology
Research keywords  (6)： 薬理学 ,  肝線維化 ,  NASH ,  肝星細胞 ,  ブレス・プリント ,  肝類洞血流
Research theme for competitive and other funds  (12)：
  • 2023 - 2026 肝星細胞における液-液相分離を標的としたNASH進行スイッチ制御の確立
  • 2022 - 2025 NASH進行のスイッチとなる肝実質細胞-肝星細胞間相互作用制御の分子機構
  • 2021 - 2024 AI搭載ガスクロマトグラフを応用した呼気分析によるNASH進行非侵襲判定法の開発
  • 2022 - 2023 香辛料食品由来PENsの抗肝線維化効果
  • 2023 - 2023 Inhibition of adenosine receptors induces the inversion of prostaglandin E2 effects on hepatic stellate cell activation
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Papers (12)：
  • Soshiro Kodera, Toshihide Kimura, Tomoki Nishioka, Yukiko K Kaneko, Momoka Yamaguchi, Kozo Kaibuchi, Tomohisa Ishikawa. GDP-bound Rab27a regulates clathrin disassembly through HSPA8 after insulin secretion. Archives of biochemistry and biophysics. 2023. 749. 109789-109789
  • Mai Kato, Momoka Yamaguchi, Akira Ooka, Ryota Takahashi, Takuji Suzuki, Keita Onoda, Yuko Yoshikawa, Yuta Tsunematsu, Michio Sato, Yasukiyo Yoshioka, et al. Non-target GC-MS analyses of fecal VOCs in NASH-hepatocellular carcinoma model STAM mice. Scientific reports. 2023. 13. 1. 8924-8924
  • Megumi Kaji, Yukiko K Kaneko, Stella Amarachi Ihim, Ran Kanoh, Moe Yamamoto, Momoka Yamaguchi, Tomohisa Ishikawa. Oral ingestion of Shiikuwasha extract suppresses diabetes progression in db/db mice by preserving β-cell mass. Frontiers in nutrition. 2023. 10. 1336133-1336133
  • Stella Amarachi Ihim, Yukiko K Kaneko, Moe Yamamoto, Momoka Yamaguchi, Toshihide Kimura, Tomohisa Ishikawa. Apigenin Alleviates Endoplasmic Reticulum Stress-Mediated Apoptosis in INS-1 β-Cells. Biological & pharmaceutical bulletin. 2023. 46. 4. 630-635
  • Yukiko K Kaneko, Ami Morioka, Misaki Sano, Maho Tashiro, Naoya Watanabe, Nahoko Kasahara, Masato Nojiri, Chihiro Ishiwatari, Kentaro Ichinose, Akira Minami, et al. Asymmetric dimethylarginine accumulation under hyperglycemia facilitates β-cell apoptosis via inhibiting nitric oxide production. Biochemical and biophysical research communications. 2022. 637. 108-116
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MISC (20)：
  • 森野純鈴, 山口桃生, 岡部磨幸, 河合佑美, 金子雪子, 柴田涼吾, 大岡央, 金沢貴憲, 石川智久. 植物由来エキソソーム様ナノ粒子が肝星細胞の活性化制御および細胞への取り込みに及ぼす影響. 生体膜と薬物の相互作用シンポジウム講演要旨集. 2023. 44th
  • 岡部磨幸, 山口桃生, 大岡央, 森野純鈴, 柴田涼吾, 金沢貴憲, 金子雪子, 石川智久. Effects of plant-derived exosome-like nanoparticles on the activation of hepatic stellate cells. 日本薬学会年会要旨集(Web). 2023. 143rd
  • 柴田涼吾, 金子雪子, 山口桃生, 森野純鈴, 金沢貴憲, 石川智久. 膵β細胞アポトーシスに対する植物由来エキソソーム様ナノ粒子の効果の検証. 次世代を担う若手のための創薬・医療薬理シンポジウムプログラム・要旨集. 2023. 2023
  • 佐藤蓮, 金子雪子, 金沢貴憲, 金沢貴憲, 芹澤未来, 大岡央, 山口桃生, 真野結奈, 飯岡真吾, 尾熊貴之, et al. 膵島に集積する脂質ナノ粒子の開発を目指したリン脂質の組成および粒子径の検討. 生体膜と薬物の相互作用シンポジウム講演要旨集. 2023. 44th
  • 森野純鈴, 山口桃生, 金沢貴憲, 飯岡真吾, 土肥直貴, 近藤啓, 石川智久. Evaluation of hepatocyte-derived exosomes on physical characteristics and uptake into hepatic stellate cells. 日本薬学会年会要旨集(Web). 2022. 142nd
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Lectures and oral presentations  (12)：
  • Treatment of hepatocytes with palmitic acid induces the release of extracellular vesicles with tropism to activated hepatic stellate cells
    (23rd International Conference on Cytochrome P450 (ICCP450) and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics (JSSX) (2023 ICCP450/JSSX International Joint meeting) 2023)
  • Analysis of the mechanism underlying the DIF-1 effect on HSCs transdifferentiation
    (19th World Congress of Basic & Clinical Pharmacology 2023 2023)
  • Inhibition of adenosine receptors induces the inversion of prostaglandin E2 effects on hepatic stellate cell
    (19th World Congress of Basic & Clinical Pharmacology 2023 2023)
  • Caffeine induces the reversion of activated hepatic stellate cells via antagonizing adenosine receptors
    (2020)
  • Hepatic stellate cells contract and regulate sinusoidal blood flow in response to the sympathetic neurotransmitter, noradrenaline.
    (50th NIPS international symposium 2019)
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Education (3)：
  • 2013 - 2017 University of Shizuoka
  • 2011 - 2013 University of Shizuoka Graduate School of Pharmaceutical Sciences
  • 2007 - 2011 University of Shizuoka School of Pharmaceutical Sciences
Professional career (1)：
  • 博士号(薬科学) (静岡県立大学)
Work history (1)：
  • 2017/04 - 現在 University of Shizuoka School of Pharmaceutical Sciences
Association Membership(s) (4)：
Shizuoka Experimental Animal Research Association ,  THE JAPANESE SOCIETY FOR THE RESEARCH OF HEPATIC CELLS ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE JAPANESE PHARMACOLOGICAL SOCIETY
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