Rchr
J-GLOBAL ID：201801008240777818   Update date: Sep. 22, 2024

Higo Shimpei

ヒゴ シンペイ | Higo Shimpei
Affiliation and department：
Nippon Medical School

About Nippon Medical School


Job title： Associate professor
Research field  (2)： Anatomy ,  Physiology
Research keywords  (4)： in situ hybridization ,  Membrane receptors ,  Endocrinology ,  Neuroscience
Research theme for competitive and other funds  (9)：
  • 2021 - 2024 Analysis of the network of NPFF receptor-expressing neurons mediating the interaction between neuroendocrine functions.
  • 2018 - 2021 環境情報入力との連関を基盤とする新規生殖機能制御系に関する分子機能形態学的解析
  • 2017 - 2021 帝王切開による出産が子の神経発達に与える影響の解析とその対処法の検索
  • 2017 - 2018 Rat whole brain mapping of NPFF receptors and its neurochemical characterization.
  • 2015 - 2018 吸入麻酔薬によるPer2発現抑制機構の解明-ICU症候群の機構解明を志向して-
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Papers (36)：
  • Masahiro Morishita, Shimpei Higo, Kinuyo Iwata, Hirotaka Ishii. Sex and interspecies differences in ESR2-expressing cell distributions in mouse and rat brains. Biology of Sex Differences. 2023. 14. 1
  • Shimpei Higo, Hirotaka Ishii, Hitoshi Ozawa. Recent Advances in High-sensitivity <i>In Situ</i> Hybridization and Costs and Benefits to Consider When Employing These Methods. ACTA HISTOCHEMICA ET CYTOCHEMICA. 2023. 56. 3. 49-54
  • 心平 肥後, 萌子 金谷, 友喜 水野, 一史 小澤, 篤裕 坂本, 寛高 石井. In situ hybridization法の高感度化手法とその神経科学未解明領域への応用. Nihon Ika Daigaku Igakkai Zasshi. 2023. 19. 2. 84-89
  • Masahiro Morishita, Shimpei Higo, Yujiro Hattori, Mina Ozawa, Mai Otsuka, Keisuke Matsumoto, Hitoshi Ozawa, Hirotaka Ishii. Immunohistochemistry for ESR2 with a mouse monoclonal antibody (PPZ0506). Journal of Nippon Medical School. 2023. 90. 2. 138-140
  • 小澤 実那, 服部 裕次郎, 肥後 心平, 大塚 真衣, 松本 恵介, 石井 寛高, 小澤 一史. 抗ヒトERβ特異的モノクローナル抗体(PPZ0506)を用いたMouse-on-Mouse免疫組織化学染色法の最適化条件の決定およびマウスERβの局在解析. 日本医科大学医学会雑誌. 2022. 18. 4. 447-448
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MISC (34)：
  • 森下雅大, 肥後心平, 岩田衣世, 石井寛高. げっ歯類の脳におけるエストロゲン受容体β発現の免疫組織学的解析. 日本組織細胞化学会総会・学術集会講演プログラム・予稿集. 2023. 64th (CD-ROM)
  • 石井寛高, 服部裕次郎, 肥後心平, 森下雅大, 小澤実那, 大塚真衣, 松本恵介, 小澤一史, 小澤一史. Impact of Well-validated Anti-human ERβ Monoclonal Antibody PPZ0506 on ERβ Research. 日本医科大学医学会雑誌. 2023. 19. 4
  • 森下雅大, 肥後心平, 岩田衣世, 石井寛高. マウスとラットの脳におけるエストロゲン受容体βの分布とその性差. 日本医科大学医学会雑誌. 2023. 19. 4
  • 石井寛高, 森下雅大, 肥後心平. 免疫組織化学法の原理と基礎. 組織細胞化学. 2023. 2023
  • 小澤実那, 小澤実那, 服部裕次郎, 石井寛高, 肥後心平, 大塚真衣, 松本恵介, 小澤一史. 抗ヒトERβ特異的モノクローナル抗体(PPZ0506)を用いたマウス組織における免疫組織化学染色法の最適化とマウスERβタンパク質の発現・局在解析. 日本解剖学会総会・全国学術集会講演プログラム・抄録集. 2022. 127th (CD-ROM)
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Lectures and oral presentations  (7)：
  • Whole brain mapping of Neuropeptide FF receptors.
    (123rd Annual Meeting of the Japanese Association of Anatomists 2018)
  • Neurochemical characterization of Gpr54-expressing neurons in the arcuate nucleus of the hypothalamus.
    (122nd Annual Meeting of the Japanese Association of Anatomists 2017)
  • NEUROCHEMICAL CHARACTERIZATION OF NEURONS EXPRESSING Kiss1r (Gpr54) IN THE FEMALE RAT HYPOTHALAMUS USING IN SITU HYBRIDIZATION AND IMMUNOFLUORECSENCE.
    (9th International Meeting STEROIDS and NERVOUS SYSTEM 2017)
  • Whole brain mapping of kisspeptin receptor and its physiological functions
    (57th Annual meeting of the Japan Society of Histochemistry and Cytochemistory 2016)
  • Co-expression analysis of Kiss1r in the Oxycontin and vasopressin neurons.
    (2016)
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Education (2)：
  • 2005 - 2010 The University of Tokyo Graduate School of Arts and Sciences
  • 2001 - 2005 The University of Tokyo College of Arts and Sciences
Professional career (1)：
  • Ph.D. (Tokyo University)
Work history (7)：
  • 2021/04 - 現在 Nippon Medical School Anatomy and Neurobiology Associate professor
  • 2017/04 - 現在 TEIKYO University of Science Part-time lecturer
  • 2017/04 - 2021/03 Nippon Medical School Anatomy and Neurobiology Senior assistant professor
  • 2011/10 - 2017/03 Nippon Medical School Anatomy and Neurobiology Assistant professor
  • 2011/04 - 2011/09 Nippon Medical School Anatomy and Neurobiology Postdoctoral fellow
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Committee career (2)：
  • 2020 - 現在 Japan Society of Histochemistry and Cytochemistry Council Member
  • 2018/10 - 現在 日本神経内分泌学会 評議員
Awards (3)：
  • 2023 - 日本組織細胞化学会 2023 年度(第 25 回)日本組織細胞化学会論文賞 Optimized Mouse-on-mouse Immunohistochemical Detection of Mouse ESR2 Proteins with PPZ0506 Monoclonal Antibody
  • 2023 - 日本組織細胞化学会 2023 年度(第 25 回)日本組織細胞化学会論文賞 Identification of Brain Regions Activated by Sevoflurane and Propofol and Regional Changes in Gene Expression
  • 2020/10 - Japan Society of Histochemistry and Cytochemistry Young Investigator Award
Association Membership(s) (6)：
日本行動神経内分泌研究会 ,  日本医科大学医学会 ,  JAPAN NEUROENDOCLINE SOCIETY ,  THE JAPANESE ASSOCIATION OF ANATOMISTS ,  JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY ,  THE JAPAN NEUROSCIENCE SOCIETY
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