Yosuke Hirakawa

ヒラカワヨウスケ | Yosuke Hirakawa

Affiliation and department：

Research field (1)： Nephrology

Research theme for competitive and other funds (7)：

2022 - 2025 Elucidation of mechanism how short chain fatty acids suppress kidney fibrosis.
2021 - 2023 Pathophysiological role of organelle contact site in tubular homeostasis
2019 - 2021 Examination of biological meaning of change in oxygen status and oxygen gradation in chronic kidney disease
2018 - 2021 Oxygen imaging of living tissues using confocal phosphorescence lifetime imaging microscope
2018 - 2021 Elucidation of metabolic reprogramming in the kidney and development of novel therapeutic approaches utilizing HIF against kidney disease

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Papers (26)：

Yasuna Nakamura, Hirotaka Matsumoto, Chia-Hsien Wu, Daichi Fukaya, Rie Uni, Yosuke Hirakawa, Mikako Katagiri, Shintaro Yamada, Toshiyuki Ko, Seitaro Nomura, et al. Alpha 7 nicotinic acetylcholine receptors signaling boosts cell-cell interactions in macrophages effecting anti-inflammatory and organ protection. Communications biology. 2023. 6. 1. 666-666
Yuka Sugawara, Yosuke Hirakawa, Hajime Nagasu, Akira Narita, Akihiro Katayama, Jun Wada, Miho Shimizu, Takashi Wada, Hiromasa Kitamura, Toshiaki Nakano, et al. Genome-wide association study of the risk of chronic kidney disease and kidney-related traits in the Japanese population: J-Kidney-Biobank. Journal of human genetics. 2022. 68. 2. 55-64
Yosuke Hirakawa, Kentaro Yoshioka, Kensuke Kojima, Yasuho Yamashita, Takuma Shibahara, Takehiko Wada, Masaomi Nangaku, Reiko Inagi. Potential progression biomarkers of diabetic kidney disease determined using comprehensive machine learning analysis of non-targeted metabolomics. Scientific Reports. 2022. 12. 1. 16287-16287
Yuka Sugawara, Yosuke Hirakawa, Koki Mise, Kosuke Kashiwabara, Ko Hanai, Satoshi Yamaguchi, Akihiro Katayama, Yasuhiro Onishi, Yui Yoshida, Naoki Kashihara, et al. Analysis of inflammatory cytokines and estimated glomerular filtration rate decline in Japanese patients with diabetic kidney disease: a pilot study. Biomarkers in medicine. 2022. 16. 10. 759-770
Yuji Sasaki, Yoshiki Higashijima, Jun-Ichi Suehiro, Takehito Sugasawa, Eri Oguri-Nakamura, Shigetomo Fukuhara, Nao Nagai, Yosuke Hirakawa, Youichiro Wada, Masaomi Nangaku, et al. Lysine demethylase 2B regulates angiogenesis via Jumonji C dependent suppression of angiogenic transcription factors. Biochemical and biophysical research communications. 2022. 605. 16-23

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MISC (2)：

木村仁美, 大木里花子, 平川陽亮, 本田謙次郎, 日向宗利, 阿部浩幸, 堂本裕加子, 南学正臣. 肺癌に対しPD-1阻害薬使用中に尿潜血および尿蛋白陽性を認めた一例. 日本腎臓学会誌. 2019. 61. 6. 732-732
Yosuke Hirakawa, Tetsuhiro Tanaka, Masaomi Nangaku. Mechanisms of metabolic memory and renal hypoxia as a therapeutic target in diabetic kidney disease. JOURNAL OF DIABETES INVESTIGATION. 2017. 8. 3. 261-271

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