2021 - 2024 Strategy for improving cancer and obesity by regulating the lipid metabolic function of PGRMC1
2015 - 2018 膜結合性ヘムタンパク質PGRMC1の構造的制御による生理機能の解明
2013 - 2018 保存血清のメタボローム解析による疾患診断の有用性の検証と応用
2018 - 膜受容体PGRMC1の構造的知見を基盤とした生理機能の解明と制御化合物の解析
2015 - 代謝システム制御分子の系統的探索による治療戦略創出と創薬展開
2011 - 2014 新規ヘム標的タンパク質HSP27の細胞防御制御機構の解明
2011 - 2013 Analysis of pathological roles of hypoxic responses in the regulation of organ metabolism in fatty liver diseases
2009 - 2011 がんの進展におけるアミノ酸代謝異常の機構解明と応用
2007 - 2009 ヘム関連ポルフィリンのミトコンドリア集積機構の解明
2007 - 2008 生命時空間ネットワーク進化型教育研究拠点
2005 - 2007 破骨細胞分化誘導因子の発現制御機構の解析とこれを標的とした骨粗鬆症薬の開発
Show all
Papers (96):
Sho Uemura, Yasuaki Kabe, Minoru Kitago, Sachiko Matsuda, Yuta Abe, Yasushi Hasegawa, Shutaro Hori, Masayuki Tanaka, Yutaka Nakano, Yasunori Sato, et al. Prognosis prediction of PDAC via detection of O-glycan altered extracellular vesicles in perioperative sera. Cancer Science. 2024
Takehiro Yamamoto, Tetsu Hayashida, Yohei Masugi, Kiyotaka Oshikawa, Noriyo Hayakawa, Mai Itoh, Chiyoko Nishime, Masami Suzuki, Aiko Nagayama, Yuko Kawai, et al. PRMT1 Sustains De Novo Fatty Acid Synthesis by Methylating PHGDH to Drive Chemoresistance in Triple-negative Breast Cancer. Cancer Research. 2024
Takashi Nakamura, Sayako Honda, Shinichirou Ito, Toshihide Mizoguchi, Takehiro Yamamoto, Masataka Kasahara, Yasuaki Kabe, Koichi Matsuo, Makoto Suematsu. Generation of bicistronic Dmp1-Cre knock-in mice using a self-cleaving 2A peptide. Journal of bone and mineral metabolism. 2023
Hiroki Yamazaki, Masaaki Uehara, Noritada Yoshikawa, Akiko Kuribara-Souta, Motohisa Yamamoto, Yasuko Hirakawa, Yasuaki Kabe, Makoto Suematsu, Hirotoshi Tanaka. The crucial role of muscle glucocorticoid signaling in accelerating obesity and glucose intolerance via hyperinsulinemia. JCI insight. 2023