Satoshi Konishi

Konishi Satoshi | Satoshi Konishi

Affiliation and department：

Research field (2)： Respiratory medicine , Cell biology

Research keywords (9)： alveolar regeneration , lung disease modeling , multi-ciliary coordination , cytoskeletal dynamics , primary culture of airway/alveolar epithelial cells , human induced pluripotent stem cells , super-resolution microscopic study , live-cell imaging , animal lung injury model

Research theme for competitive and other funds (4)：

2024 - 2029 精密切断肺スライス培養を用いた肺線維症におけるtransitional stem cell stateの線維化駆動メカニズムの解明
2024 - 2026 精密切断肺スライス培養を用いた遷移性幹細胞状態の蓄積による肺線維症誘導機構の解明
2020 - 2022 Generation of airway submucosal gland cells from human iPS cells and their application to disease
2017 - 2019 The establishment of intercellular co-ordination of ciliary movement by using human iPS cell-derived airway epithelial cells

Papers (22)：

Issei Oi, Isao Ito, Naoya Tanabe, Satoshi Konishi, Yumiko Ibi, Yu Hidaka, Nobuyoshi Hamao, Masahiro Shirata, Kensuke Nishioka, Seiichiro Imai, et al. Investigation of predictors for in-hospital death or long-term hospitalization in community-acquired pneumonia with risk factors for aspiration. European Clinical Respiratory Journal. 2024. 11. 1
Gen Shiratsuchi, Satoshi Konishi, Tomoki Yano, Yuichi Yanagihashi, Shogo Nakayama, Tatsuya Katsuno, Hiroka Kashihara, Hiroo Tanaka, Kazuto Tsukita, Koya Suzuki, et al. Dual-color live imaging unveils stepwise organization of multiple basal body arrays by cytoskeletons. EMBO Reports. 2024
Arvind Konkimalla, Satoshi Konishi, Lauren Macadlo, Yoshihiko Kobayashi, Zachary J. Farino, Naoya Miyashita, Léa El Haddad, Jeremy Morowitz, Christina E. Barkauskas, Pankaj Agarwal, et al. Transitional cell states sculpt tissue topology during lung regeneration. Cell Stem Cell. 2023. 30. 11. 1486-1502.e9
Arvind Konkimalla, Zachary Elmore, Satoshi Konishi, Lauren Macadlo, Hiroaki Katsura, Aleksandra Tata, Aravind Asokan, Purushothama Rao Tata. Efficient AAV Mediated Transgenesis in Alveolar Stem Cells and Associated Niches. American journal of respiratory cell and molecular biology. 2023
Issei Oi, Isao Ito, Naoya Tanabe, Satoshi Konishi, Nobuyoshi Hamao, Masahiro Shirata, Seiichiro Imai, Yoshiro Yasutomo, Seizo Kadowaki, Hisako Matsumoto, et al. Protein C activity as a potential prognostic factor for nursing home-acquired pneumonia. PLOS ONE. 2022. 17. 10. e0274685-e0274685

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MISC (2)：

小西聡史, 後藤慎平. 肺のオルガノイド化とその医学応用への可能性-呼吸器における幹細胞研究の新展開. 医学のあゆみ. 2018. 264. 8
Generation of Airway Epithelial Cells from Human Induced Pluripotent Stem Cells. 2016. 64. 8. 785-789

Patents (3)：

多列繊毛気道上皮細胞、分化誘導法および製造方法
肺胞上皮細胞の分化誘導法
気道上皮細胞の分化誘導法

Lectures and oral presentations (6)：

微小管の束化が呼吸器再生における肺胞上皮細胞の三次元形態変化を制御する
(第97回日本生化学会大会「シンポジウム:上皮管腔組織のダイナミクスと恒常性の制御機構」 2024)
Ex vivo培養系及びin vivo障害モデルを用いた呼吸器再生メカニズムの探求
(第5回「医学と数理」研究会 2024)
Ex vivo四次元イメージングを用いた呼吸器組織再生メカニズムの探求
(第40回日本DDS学会学術集会「シンポジウム:DDS研究のためのex vivo三次元組織形成技術」 2024)
一過性に出現する遷移的な細胞状態が肺胞再生における組織再構築を規定する
(第64回日本呼吸器学会学術講演会「若手呼吸器研究最前線シンポジウム」 2024)
高解像ライブセルイメージングによる気道多繊毛協調運動構築原理の解明
(第92回日本生化学会大会「シンポジウム:細胞の上皮性を決定・維持する多面的な分子機構」 2019)

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Education (2)：

2012 - 2016 Kyoto University Graduate School of Medicine Department of Respiratory Medicine
2001 - 2007 Kyoto University Faculty of Medicine Department of Medical Science

Professional career (1)：

医学博士 (京都大学)

Work history (8)：

2023/12 - 現在京都大学iPS細胞研究所臨床応用研究部門後藤研究室特定拠点助教
2020/01 - 2023/11 Duke University Department of Cell Biology
2016/04 - 2020/03 Kyoto University Faculty of Medicine Department of Respiratory Medicine Visiting Researcher
2019/04 - 2020/01 Japanese Red Cross Wakayama Medical Center Department of Respiratory Medicine Respiratory Physician
2019/04 - 2020/01 Osaka University Graduate School of Frontier Biosciences Project Lecturer

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Awards (6)：

2022 - Duke University Department of Cell Biology Retreat Best Microscopic Image Award
2017 - 第8回大阪大学大学院生命機能研究科若手研究フォーラムベストプレゼンテーション賞
2017 - 京都大学医学部若手研究者優秀論文賞(KMYIA)
2016 - NPO法人西日本呼吸器内科医療推進機構第10回研究部門奨励賞
2015 - IREF Young Investigator's Award

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