Norifumi Takeda

Affiliation and department：
Job title： Assistant Professor

Research field (5)： Developmental biology , Hygiene and public health (non-laboratory) , Genetics , Molecular biology , Cardiology

Research theme for competitive and other funds (19)：

2023 - 2025 肺内皮細胞の老化シグナル活性化による肺動脈性肺高血圧症の進展機序の解明
2022 - 2024 Role of pulmonary endothelial dysfunction in idiopathic pulmonary hypertension
2021 - 2024 時空間的マルチスケールイメージングを用いた遺伝性肺動脈性肺高血圧症における微小血管リモデリングの意義の解明およびその治療応用についての検討
2018 - 2023 マルチオミックス連関による循環器疾患における次世代型精密医療の実現
2019 - 2022 Pathophysiological role of inflammatory and metabolic signals during aortic aneurysm formation in Marfan syndrome

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Papers (241)：

Takashi Hiruma, Shunsuke Inoue, Toshiyuki Ko, Seitaro Nomura, Ryo Abe, Chie Bujo, Junichi Ishida, Norifumi Takeda, Eisuke Amiya, Masaru Hatano, et al. PRKAG2 Syndrome Caused by a Novel Missense Variant Mimicked Sporadic Hypertrophic Cardiomyopathy Until Its Progression to Burned-Out Phase. Circulation. Heart failure. 2024. e012047
Kensuke Ueno, Hidehiro Kaneko, Kentaro Kamiya, Akira Okada, Masaaki Konishi, Teruhiko Imamura, Yuta Suzuki, Katsuhito Fujiu, Norifumi Takeda, Hiroyuki Morita, et al. The Benefits of Early Rehabilitation for Patients With Acute Heart Failure Requiring IV Inotropic Drugs. Critical care medicine. 2024
Yuta Suzuki, Hidehiro Kaneko, Akira Okada, Toshiyuki Ko, Takahiro Jimba, Katsuhito Fujiu, Norifumi Takeda, Hiroyuki Morita, Jin Komuro, Masaki Ieda, et al. Association of SGLT2 Inhibitors with Incident Cancer. Diabetes & Metabolism. 2024. 101585-101585
Toshiyuki Ko, Hidehiro Kaneko, Yuta Suzuki, Akira Okada, Tatsuhiko Azegami, Katsuhito Fujiu, Norifumi Takeda, Hiroyuki Morita, Takashi Yokoo, Kaori Hayashi, et al. Dose-dependent association between estimated glomerular filtration rate and the subsequent risk of depression: An analysis of a nationwide epidemiological dataset. European journal of clinical investigation. 2024. e14322
Takashi Hiruma, Shunsuke Inoue, Zhehao Dai, Seitaro Nomura, Toru Kubo, Kenta Sugiura, Atsushi Suzuki, Takeshi Kashimura, Shouji Matsushima, Takanobu Yamada, et al. Association of Multiple Nonhypertrophic Cardiomyopathy-Related Genetic Variants and Outcomes in Patients With Hypertrophic Cardiomyopathy. JACC: Heart Failure. 2024

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MISC (205)：

武田憲文. 【循環器疾患に対する遺伝子診断と治療Up to date】識る胸部大動脈瘤・解離症のゲノム医療の現状と課題. Heart View. 2024. 28. 5. 446-452
小室仁, 金子英弘, 鈴木裕太, 岡田啓, 水野篤, 藤生克仁, 武田憲文, 森田啓行, 西山成, 矢野裕一朗, et al. 循環器疾患啓発・診断・治療におけるbeyond 5G(How to Increase Health Literacy beyond 5G: Importance of Disease Awareness). 日本循環器学会学術集会抄録集. 2024. 88回. SY25-4
皆月隼, 波多野将, 廣瀬和俊, 齊藤暁人, 八木宏樹, 武田憲文, 森田啓行, 小室一成. Analysis of Balloon Pulmonary Angioplasty in Inoperable Chronic Thromboembolic Pulmonary Hypertension Patients with Low DLco(タイトル和訳中). 日本循環器学会学術集会抄録集. 2024. 88回. OJ20-6
廣瀬和俊, 皆月隼, 齊藤暁人, 八木宏樹, 武田憲文, 波多野将, 森田啓行, 小室一成. Impact of Balloon Angioplasty on Hemodynamics and Quality-of-life Status in Patients with Chronic Thromboembolic Pulmonary Hypertension and Psychiatric Disorders(タイトル和訳中). 日本循環器学会学術集会抄録集. 2024. 88回. OJ20-8
廣瀬和俊, 桐山皓行, 長江祐吾, 蛭間貴司, 小林敦, 佐藤将敬, 澤野晋之介, 加門辰也, 篠原宏樹, 三浦瑞樹, et al. Cardiovascular Outcomes after Percutaneous Coronary Intervention in Patients with Systemic Sclerosis: A Case-control Study(タイトル和訳中). 日本循環器学会学術集会抄録集. 2024. 88回. PJ111-2

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Patents (1)：

新規化合物、並びにそれを有効成分とする心筋細胞増殖誘導剤及び心筋の機能障害を伴う疾患の治療剤

Lectures and oral presentations (214)：

FBN1レアバリアントによって発症した非症候群性大動脈瘤・解離患者の臨床的特徴
(第272回日本循環器学会関東甲信越地方会 2024)
画像問題を含む循環器内科専門医試験におけるGPTの性能評価
(第272回日本循環器学会関東甲信越地方会 2024)
Cardiovascular Outcomes after Percutaneous Coronary Intervention in Patients with Systemic Sclerosis: A Case-control Study
(2024)
Association between Remnant Cholesterol and Incident Atherosclerotic Cardiovascular Disease, Heart Failure, and Atrial Fibrillation
(2024)
How to Increase Health Literacy beyond 5G -Importance of Disease Awareness
(2024)

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Education (4)：

2002 - 2006 The University of Tokyo
1994 - 1998 The University of Tokyo
1992 - 1994 The University of Tokyo
1989 - 1992 愛媛県立今治西高等学校

Professional career (1)：

MD, PhD (University of Tokyo)

Work history (12)：

2021/06 - 現在東京大学医学部附属病院マルファン症候群センター長(兼任)
2016/09 - 現在 The University of Tokyo Hospital Senior Lecturer
2020/04 - 2023/10 東京大学医学部附属病院循環器内科医局長
2015/04 - 2016/08 The University of Tokyo Hospital Department of Cardiovascular Medicine Assistant Professor
2013/04 - 2015/03 The University of Tokyo Hospital Assistant Professori

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Awards (10)：

2022/03 - 東京大学医学部附属病院令和3年度東大病院アワード(個人部門)ベストスタッフ賞
2017/12 - 第21回日本心血管内分泌代謝学会高峰譲吉研究奨励賞
2017/11 - 日本医師会平成29年度日本医師会医学研究奨励賞
2011 - 東京都医師会グループ研究賞マルファン症候群患者の総合的診療体制の確立
2010/04 - 東京大学医師会平成21年度東京大学医師会医学賞

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Association Membership(s) (13)：

The Japanese Vascular Biology and Medicine Organization , The Society of Cardiovascular Endocrinology and Metabolism , International Society for Heart Research , Japanese Society for Adult Congenital Heart Disease , THE JAPANESE SOCIETY OF INFLAMMATION AND REGENERATION , JAPANESE HEART FAILURE SOCIETY , Japanese College of Cardiology , The Japanese Circulation Society , THE JAPANESE SOCIETY OF INTERNAL MEDICINE , 日本小児循環器学会 , 日本脈管学会 , American Heart Association , European Society of Cardiology

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