Rchr
J-GLOBAL ID：201801008473046570
Update date: Jun. 03, 2024
Mizushima Tsunekazu
ミズシマ ツネカズ | Mizushima Tsunekazu
Affiliation and department：
Job title：
Professor
Other affiliations (1)：
Research field (1)：
Digestive surgery
Research theme for competitive and other funds (13)：
- 2023 - 2026 炎症性発癌における自然リンパ球の役割解明
- 2022 - 2025 Elucidation of Epithelial Dysfunction in Response to Intestinal Microbiota in Inflammatory Bowel Diseases
- 2021 - 2024 Reconstruction and the analysis of tumor stroma using ex vivo tumor model
- 2018 - 2021 Development of miRNA-based immunotherapy in cancer
- 2017 - 2020 Biological Features of Inflammatory Bowel Disease-Associated Colorectal Cancer and the Association of Innate Lymphoid Cells
- 2017 - 2020 The effects of Atg5-independent autophagy activator on DSS-induced colitis in mice
- 2017 - 2019 Development of colon cancer stem cell target therapy by inhibiting autolysosome activity
- 2015 - 2019 Proteasome activity and autophagy which relate to cancer stemness and treatment resistance
- 2014 - 2018 A novel noninvasive screening assay for RAS mutations in the peripheral blood sample using next-generation sequencing for anti-EGFR antibodies therapy
- 2014 - 2017 Feasibility and efficacy of autologous adipose-derived stem cell therapy for inflammatory bowel disease patients
- 2011 - 2013 Clinical application of gene expression signature as a predictor of recurrence in colorectal cancer
- 2010 - 2012 Resarch for the mechanisms of induction and differentiation of mucosal immune cells in the patients with inflammatory bowel diseases
- 2009 - 2011 Carbon dioxide insufflating endoscopy for patients with inflammatory bowel diseases : safety and efficacy study
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Papers (1,002)：
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Tadafumi Asaoka, Kenta Furukawa, Manabu Mikamori, Satoshi Hyuga, Tomofumi Ohashi, Iwamoto Kazuya, Yujiro Nakahara, Atsushi Naito, Hidekazu Takahashi, Jeongho Moon, et al. Portal vein wedge resection and patch venoplasty with autologous vein grafts for hepatobiliary-pancreatic cancer. Surgical case reports. 2024. 10. 1. 27-27
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Shiki Fujino, Norikatsu Miyoshi, Aya Ito, Rie Hayashi, Masayoshi Yasui, Chu Matsuda, Masayuki Ohue, Masafumi Horie, Shinichi Yachida, Jun Koseki, et al. Metastases and treatment-resistant lineages in patient-derived cancer cells of colorectal cancer. Communications Biology. 2023. 6. 1
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荻野 崇之, 水島 恒和, 藤井 誠, 関戸 悠紀, 土岐 祐一郎, 江口 英利, 野口 竜剛, 杉原 健一, 味岡 洋一, 石原 聡一郎. IBD関連大腸腫瘍の診断と治療戦略 クローン病関連大腸癌の予後と再発形式. 日本大腸肛門病学会雑誌. 2023. 76. 9. A63-A63
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荻野 崇之, 水島 恒和, 藤井 誠, 関戸 悠紀, 土岐 祐一郎, 江口 英利, 野口 竜剛, 杉原 健一, 味岡 洋一, 石原 聡一郎. IBD関連大腸腫瘍の診断と治療戦略 クローン病関連大腸癌の予後と再発形式. 日本大腸肛門病学会雑誌. 2023. 76. 9. A63-A63
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Takehiro Noda, Hidekazu Takahashi, Mitsuyoshi Tei, Naohiro Nishida, Taishi Hata, Yutaka Takeda, Masayuki Ohue, Hiroshi Wada, Tsunekazu Mizushima, Tadafumi Asaoka, et al. Clinical outcomes of neoadjuvant chemotherapy for resectable colorectal liver metastasis with intermediate risk of postoperative recurrence: A multi-institutional retrospective study. Annals of gastroenterological surgery. 2023. 7. 3. 479-490
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MISC (1,055)：
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Masatoshi Kitakaze, Masamitsu Konno, Ayumu Asai, Ryota Chijimatsu, Shiki Fujino, Takayuki Ogino, Hidekazu Takahashi, Norikatsu Miyoshi, Mamoru Uemura, Taroh Satoh, et al. Single-cell analysis of immune cells in tumor reveals the function of resident memory T cells in colorectal tumor. CANCER SCIENCE. 2022. 113
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太田博文, 中田健, 小森孝通, 笹生和宏, 賀川義規, 森田俊治, 能浦真吾, 林伸泰, 植村守, 松田宙, et al. パニツムマブ皮膚障害予防策としてのスキンケアとクラリスロマイシン内服投与の効果. 日本臨床外科学会雑誌. 2021. 82. Supplement (Web)
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Yuki Sekido, Junichi Nishimura, Kazuhiro Nakano, Takeaki Osu, Cheryl-Emiliane T Chow, Hiroshi Matsuno, Takayuki Ogino, Shiki Fujino, Norikatsu Miyoshi, Hidekazu Takahashi, et al. Some Gammaproteobacteria are enriched within CD14+ macrophages from intestinal lamina propria of Crohn's disease patients versus mucus. Scientific reports. 2020. 10. 1. 2988-2988
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水島恒和, 水島恒和, 安枝明日香, 荻野崇之, 吉原輝一, 森良太, 藤本侑士, 藤野志季, 三吉範克, 高橋秀和, et al. The relationship between preoperative sarcopenia and postoperative complications in patients with Crohn’s disease. 日本外科感染症学会雑誌(Web). 2020. 17. 5
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水島恒和, 水島恒和, 渡部嘉文, 池田敦世, 安枝明日香, 藤本侑士, 藤野志季, 荻野崇之, 三吉範克, 高橋秀和, et al. ヒト腸管疑似無菌モデルによる腸内細菌叢の腸管上皮・粘膜免疫に対する役割およびクローン病における意義の検討. 日本消化器病学会雑誌(Web). 2020. 117
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Work history (1)：
- 2024/05 - 現在 Dokkyo Medical University Department of Colorectal Surgery Professor
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