Rchr
J-GLOBAL ID：201801008616423940
Update date: Feb. 29, 2024
MIKAMI YU
ミカミ ユウ | MIKAMI YU
Research field (3)：
Cell biology
, Respiratory medicine
, Molecular biology
Research keywords (9)：
間質性肺炎
, ENaC
, SCNN1G
, NCFB
, 慢性低酸素
, COPD
, 気道炎症
, 嚢胞性線維症
, 気管支喘息
Research theme for competitive and other funds (4)：
- 2020 - 2022 Gene transduction efficiency in hypoxic CF airway epithelia
- 2018 - 2019 サーファクタント脂質合成酵素に着目した肺気腫形成の解明
- 2015 - 2017 Contribution of LTBR signaling for development of COPD
- 2016 - 2017 喫煙刺激による肺気腫性変化形成におけるサーファクタント脂質の役割の解明
Papers (50)：
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Takanori Asakura, Kenichi Okuda, Gang Chen, Hong Dang, Takafumi Kato, Yu Mikami, Stephen A Schworer, Rodney C Gilmore, Giorgia Radicioni, Padraig Hawkins, et al. Proximal and Distal Bronchioles Contribute to the Pathogenesis of Non-Cystic Fibrosis Bronchiectasis (NCFB). American Journal of Respiratory and Critical Care Medicine. 2023
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Yu Mikami, Barbara R. Grubb, Troy D. Rogers, Hong Dang, Takanori Asakura, Pradeep Kota, Rodney C. Gilmore, Kenichi Okuda, Lisa C. Morton, Ling Sun, et al. Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration. Science Translational Medicine. 2023. 15. 699
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Takafumi Kato, Takanori Asakura, Caitlin E Edwards, Hong Dang, Yu Mikami, Kenichi Okuda, Gang Chen, Ling Sun, Rodney C Gilmore, Padraig Hawkins, et al. Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease. American journal of respiratory and critical care medicine. 2022
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Takae Tanosaki, Yu Mikami, Hideo Shindou, Tomoyuki Suzuki, Tomomi Hashidate-Yoshida, Keisuke Hosoki, Shizuko Kagawa, Jun Miyata, Hiroki Kabata, Katsunori Masaki, et al. Lysophosphatidylcholine Acyltransferase 1 Deficiency Promotes Pulmonary Emphysema via Apoptosis of Alveolar Epithelial Cells. Inflammation. 2022
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Oisin F McElvaney, Takanori Asakura, Suzanne L Meinig, Jose L Torres-Castillo, Robert S Hagan, Claudie Gabillard-Lefort, Mark P Murphy, Leigh B Thorne, Alain Borczuk, Emer P Reeves, et al. Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications. EBioMedicine. 2022. 77. 103894-103894
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MISC (32)：
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田野崎 貴絵, 三上 優, 進藤 英雄, 鈴木 知之, 細木 敬祐, 加川 志津子, 宮田 純, 加畑 宏樹, 正木 克宜, 長瀬 隆英, et al. 呼吸器病学の若手研究最前線 肺気腫におけるリゾリン脂質アシル転移酵素LPCAT1の役割の解明. 日本呼吸器学会誌. 2022. 11. 増刊. 45-45
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田野崎 貴絵, 三上 優, 進藤 英雄, 鈴木 知之, 細木 敬祐, 加川 志津子, 宮田 純, 加畑 宏樹, 正木 克宜, 長瀬 隆英, et al. 呼吸器病学の若手研究最前線 肺気腫におけるリゾリン脂質アシル転移酵素LPCAT1の役割の解明. 日本呼吸器学会誌. 2022. 11. 増刊. 45-45
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Hideaki Sago, Akihisa Mitani, Shiho Kohno, Saki Nagoshi, Taro Ishimori, Minako Saito, Hiroyuki Tamiya, Yu Mikami, Taisuke Jo, Go Tanaka, et al. Japanese herbal medicine Hochu-ekki-to (TJ-41) attenuates lung inflammation in lung emphysema. EUROPEAN RESPIRATORY JOURNAL. 2019. 54
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Minako Saito, Akihisa Mitani, Taro Ishimori, Hideaki Isago, Yu Mikami, Satoshi Noguchi, Yasuyuki Morishita, Takahide Nagase. Mechanistic target of rapamycin enhances fibrosis in lung by promoting epithelial mesenchymal transition. EUROPEAN RESPIRATORY JOURNAL. 2019. 54
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Taro Ishimori, Akihisa Mitani, Shiho Kohno, Saki Nagoshi, Minako Saito, Hideaki Isago, Hiroyuki Tamiya, Yu Mikami, Takashi Ishii, Taisuke Jo, et al. Sirtuin3 reduces acute lung inflammation and emphysematous aggravation in COPD exacerbation mouse model. EUROPEAN RESPIRATORY JOURNAL. 2019. 54
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Lectures and oral presentations (2)：
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LAMP法について
(第25回関東甲信地区微生物検査研修会 2011)
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LAMP法による結核菌群検出試薬の臨床応用
(第86回日本結核病学会総会 ランチョンセミナー 2011)
Education (1)：
- 2011 - 2014 The University of Tokyo Graduate School of Medicine Department of Respiratory Medicine
Professional career (1)：
Work history (3)：
- 2022/06 - 現在 The University of Tokyo Faculty of Medicine University Hospital Respiratory Medicine Assistant Professor
- 2019/05 - 2022/05 University of North Carolina at Chapel Hill Marsico Lung Institute/Cystic Fibrosis Research Center Postdoctoral Research Associate
- 2014/04 - 2019/03 The University of Tokyo Faculty of Medicine University Hospital Clinical Laboratory Center
Awards (6)：
Association Membership(s) (5)：
American Thoracic Society
, 日本結核・非結核性抗酸菌症学会 (認定医)
, 日本アレルギー学会 (専門医)
, 日本呼吸器学会 (専門医)
, 日本内科学会 (総合内科専門医)
