Ishino Kousuke

イシノコウスケ | Ishino Kousuke

Affiliation and department：
Job title：講師
Homepage URL (1)： https://www.nms.ac.jp/college/schoolroom/kisoigaku/tougyokikou/member.html

Research field (3)： Environmental effects of chemicals , Environmental effects of radiation , Experimental pathology

Research keywords (11)： Proteomics , Cancer Metabolism , DNA adductome analysis , Antioxidant metabolite , 2-Deoxy-D-glucose , Oxidative Stress , DNA adduct , DNA adduct database , LC-MS/MS , Short-chain aldehyde , Mouse monoclonal antibody1

Research theme for competitive and other funds (3)：

2017 - 2021 ホルマリン保存試料中の薬物分布-代謝物・分解物の予測・検索データベースの構築-
2017 - 2020 がん代謝で制御される抗酸化代謝フラックスが抗がん剤耐性に及ぼす影響
2011 - 2014 ナノ粒子により生成されるDNA損傷と変異誘発メカニズムの解析

Papers (40)：

Watanabe K, Komiya M, Obikane A, Miyazaki T, Ishino K, Ikegami K, Hashizume H, Ishitsuka Y, Fukui T, Gi M, et al. Development of a genotoxicity;carcinogenicity assessment method by DNA adductome analysis. Mutat Res Genet Toxicol Environ Mutagen. 2024. 899. 503821
Takahiro Haruna, Mitsuhiro Kudo, Kousuke Ishino, Junji Ueda, Yukako Shintani-Domoto, Daigo Yoshimori, Takenori Fuji, Yoko Kawamoto, Kiyoshi Teduka, Taeko Kitamura, et al. Molecular biological role of epithelial splicing regulatory protein 1 in intrahepatic cholangiocarcinoma. Hepatology research : the official journal of the Japan Society of Hepatology. 2024
Ai Yoshioka, Yukako Shintani-Domoto, Ishino Kousuke, Akiharu Kubo, Makoto Kunisada. A case of nodular cutaneous amyloidosis presenting as refractory leg skin ulcers. The Journal of dermatology. 2024. 51. 6. e211-e213
Yukako Shintani-Domoto, Kousuke Ishino, Takenori Fujii, Taeko Kitamura, Kiyoshi Teduka, Hironobu Naiki, Takashi Sakatani, Ryuji Ohashi. Immunohistochemical Diagnosis of Amyloid Typing: Utility and Limitations as Determined by Liquid Chromatography-Tandem Mass Spectrometry. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. 2024. 91. 3. 261-269
石野孔祐, 大橋隆治. オミクス解析を用いたバイオマーカー開発から空間的分子解析による形態理解へ. 日本医科大学医学会雑誌. 2023. 19. 2. 78-83

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MISC (33)：

中嶋亘, 石野孔祐, 宮崎海, 大橋隆治, 山本林. Identification of Immune Checkpoint Inhibitor Therapeutic Resistance Factors in EGFR-mutated Non-Small Cell Lung Cancer. 日本癌学会学術総会抄録集(Web). 2023. 82nd
中嶋亘, 石野孔祐, 中道真仁, 松本優, 大橋隆治, 山本林. Elucidation of the mechanism of drug resistance acquisition in EGFR-Mutated Lung Adenocarcinoma. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
湯川廉樹, 石野孔祐, 呉壮香, 北村妙子, 河本陽子, 手塚潔, 藤井雄文, 工藤光洋, 大橋隆治, 中嶋亘. 甲状腺未分化癌細胞におけるメトホルミンによる増殖抑制とオートファジーの関係性の解析. 日本医科大学医学会雑誌. 2023. 19. 4
石野孔祐, 工藤光洋, 大橋隆治. 膵癌細胞株において2-デオキシグルコースはヘキソサミン合成経路を介して小胞体ストレス関連細胞死を誘発する. 日本医科大学医学会雑誌. 2021. 17. 4. 265-266
呉壮香, 石野孔祐, 工藤光洋, 大橋隆治. 甲状腺未分化癌細胞株におけるmTOR・PDIA3同時阻害の細胞増殖への影響の検討. 日本医科大学医学会雑誌. 2021. 17. 4. 268-268

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Books (1)：

酸化ストレスの医学第一版(吉川敏一監修)
診断と治療社 2008 ISBN:9784787816566

Lectures and oral presentations (84)：

Examination of interactions affecting epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma
(2024)
The effects of CAF-derived exosomes on biological behavior and protein expression of pancreatic cancer cells
(2024)
Comprehensive Proteomic Investigation for Identifying Novel Pancreatic Cancer Tumor Markers in Liquid Samples
(2024)
Analysis of Immune Checkpoint Inhibitor Therapeutic Resistance Factors in EGFR-mutated Non-Small Cell Lung Cancer
(2024)
Search for potential biomarkers for pancreatic cancer using proteomics of conditioned media
(2024)

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Education (1)：

2006 - 2010 Nagoya university

Professional career (1)：

Doctor of Agricultural Science (Nagoya University)

Work history (9)：

2018/10 - 現在 Nippon Medical School Graduate School of Medicine Department of Integrated Diagnostic Pathology Senior Assistant Professor (Lecturer)
2018/10 - 現在 Nippon Medical School Department of Integrated Diagnostic Pathology Senior Assistant Professor (Lecturer)
2016/04 - 現在 Hakujikai School of Nursing Part-time Lecturer
2015/04 - 2023/08 Junior College of Kagawa Nutrition University Part-time Lecturer
2013/07 - 2018/09 Nippon Medical School Depatment of Integrated Diagnostic Pathology Assistant Professor

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Awards (2)：

2016/06 - 日本毒性学会ファイザー賞(共同研究者)
2007/12 - The 4th Joint Meeting of the Society for Free Radical Research Australasia and Japan Young Investigator Award

Association Membership(s) (7)：

THE JAPANESE BIOCHEMICAL SOCIETY , THE JAPANESE SOCIETY OF TOXICOLOGY , 日本プロテオーム学会 , THE JAPANESE SOCIETY OF PATHOLOGY , THE JAPANESE ENVIRONMENTAL MUTAGEN SOCIETY , THE JAPANESE CANCER ASSOCIATION , JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY

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