Yasuo Shiohama

シオハマヤスオ | Yasuo Shiohama

Research field (5)： Nanobioscience , Genomics , Tumor biology , Immunology , Virology

Research theme for competitive and other funds (6)：

2023 - 2026 Creation of Nanomulti sensitization cascade radiotherapy against the cytoskeleton and intracellular organelles
2021 - 2024 新たな実験モデル構築による嫌気性廃水処理システム活性化を担う嫌気性原虫の機能解明
2020 - 2023 Development of hyperthermia radiation multi-theranostics nanoparticles highly accumulated in malignant melanoma
2020 - 2021 嫌気性原生動物(繊毛虫)におけるメタン生成菌の細胞内共生メカニズムの解明
2014 - 2016 HTLV-1由来のHBZ蛋白を標的とした新規HTLV-1関連疾患の発症予防・治療法に関する研究

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Papers (17)：

Junna Nakamura, Yasuo Shiohama, Daniel Röth, Tomohiro Haruta, Yukari Yamashita, Tomohiro Mitsuzono, Chihiro Mochizuki, Markus Kalkum, Michihiro Nakamura. Size and Surface Properties of Functionalized Organosilica Particles Impact Cell-Particle Interactions Including Mitochondrial Activity. ACS Applied Materials & Interfaces. 2024
Yasuo Shiohama, Junna Nakamura, Michihiro Nakamura. Cellular Distribution and Intracellular Localization of Different Sizes of Fluorescent Thiol-Organosilica Particles in Mouse Lungs. ACS Applied Materials & Interfaces. 2024
Michihiro Nakamura, Chihiro Mochizuki, Chika Kuroda, Yasuo Shiohama, Junna Nakamura. Size effect of fluorescent thiol-organosilica particles on their distribution in the mouse spleen. Colloids and surfaces. B, Biointerfaces. 2023. 228. 113397-113397
Yasuo Shiohama, Ryosuke Fujita, Maika Sonokawa, Masaaki Hisano, Yojiro Kotake, Marija Krstic-Demonacos, Constantinos Demonacos, Gengo Kashiwazaki, Takashi Kitayama, Masayuki Fujii. Elimination of Off-Target Effect by Chemical Modification of 5'-End of siRNA. Nucleic acid therapeutics. 2022. 32. 5. 438-447
Yasuo Shiohama, Kazutaka Takeshita, Yuga Hirakata, Masaru K Nobu, Michihiro Ito, Naoya Shinzato. Complete Genome Sequence of "Candidatus Hydrogeosomobacter endosymbioticus," an Intracellular Bacterial Symbiont of the Anaerobic Ciliate Scuticociliate GW7. Microbiology resource announcements. 2022. 11. 2. e0115021

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MISC (17)：

中村純奈, 望月ちひろ, 塩浜康雄, 中村教泰. 多機能ナノ粒子のサイズと表面構造によるマクロファージのミトコンドリア活性の制御. 日本解剖学会総会・全国学術集会抄録集(CD-ROM). 2023. 128th
藤井政幸, 神武洋二郎, 塩浜康雄. Effect of 5’-Modification on the Asymmetry Recognition of siRNA and the Elimination of Off-Target Effect. 日本薬学会年会要旨集(Web). 2023. 143rd
藤井政幸, 神武洋二郎, 塩浜康雄. 核酸医薬によるKRAS(G12D)の選択的発現制御. 医療薬学フォーラム講演要旨集. 2023. 31st
藤井政幸, 塩浜康雄. Gapmer ASOおよびsiRNAによるKRAS遺伝子1塩基変異の識別. 日本核酸医薬学会年会講演要旨集. 2019. 5th
藤田崇史, 塩浜康雄, 藤井政幸. DNAマルチコンジュゲートのユニバーサル合成法. 日本核酸医薬学会年会講演要旨集. 2018. 4th

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Patents (1)：

ヒトT細胞白血病ウイルスHBZ蛋白質の検出方法

Lectures and oral presentations (30)：

Cellular Distribution and Intracellular Localization of Different Sizes of Fluorescent Thiol-Organosilica Particles in the Mouse Lungs
(2023)
Effect of 5’-Modification of siRNA on the Asymmetry Recognition and the Elimination of Off-Target Effect
(2023)
多機能ナノ粒子のサイズと表面構造によるマクロファージのミトコンドリア活性の制
(第128回日本解剖学会総会・全国学術集会 2023)
嫌気性繊毛虫共生体Ca. Hydrogenosomobacter endosymbioticusのゲノム性状
(日本微生物生態学会第35回大会 2022)
5’-末端化学修飾によるsiRNA対称性認識と鎖選択への影響
(日本核酸医薬学会第7回年会 2022)

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Education (4)：

2009 - 2013 Hokkaido University
2007 - 2009 University of the Ryukyus
2003 - 2007 University of the Ryukyus Faculty of Science Department of Physics and Earth Sciences, Physics Program
1999 - 2002 沖縄県立名護高等学校

Professional career (1)：

博士(医学) (北海道大学)

Work history (6)：

2022/06 - 2024/04 Yamaguchi University Department of Organ Anatomy and Nanomedicine, Graduate School of Medicine Assistant Professor
2022/06 - 2024/03 University of the Ryukyus Tropical Biosphere Research Center
2019/10 - 2022/05 University of the Ryukyus Environmental and Biological Information Group, Tropical Biosphere Research Center Postdoctoral Researcher
2018/04 - 2019/09 Kindai University Faculty of Humanity-Oriented Science and Engineering, Department of Biological and Environmental Chemistry
2016/04 - 2018/03 Kyushu University Medical Institute of Bioregulation

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Awards (3)：

2020/08 - 公益信託宇流麻学術研究助成基金研究助成金嫌気性原生動物(繊毛虫)におけるメタン生成菌の細胞内共生メカニズムの解明
2014/07 - 公益財団法人川崎医学・医療福祉学振興会教育研究助成 HAM患者由来完全ヒト抗体を用いたHTLV-1関連疾患の新規感染防止・治療法の開発
2014/05 - 公益財団法人ウエスコ学術振興財団学術研究費助成 HTLV-1由来のHBZ蛋白を標的とした新規HTLV-1関連疾患の発症予防・治療法に関する研究

Association Membership(s) (8)：

Japan Nanomedicine Society,JNS , 日本核酸化学会 , The Japanese Association of Anatomists , THE JAPANESE SOCIETY FOR VIROLOGY , THE JAPANESE CANCER ASSOCIATION , The Society of Nano Science and Technology , 日本微生物生態学会 , 日本臨床ウイルス学会

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