Matsuda Yukiko

マツダユキコ | Matsuda Yukiko

Affiliation and department：
Job title： Research Scientist
Other affiliations (1)：

Hiroshima University Research Institute for Radiation Biology and Medicine Visiting Associate Professor

Research field (4)： Genomics , Radiology , Neuroscience - general , Neuropathology

Research keywords (1)：ゲノム科学神経変性疾患

Research theme for competitive and other funds (5)：

2022 - 2025 Whole-genome sequence analysis of radiation-induced mutations in human hematopoietic stem cells
2020 - 2022 Study on Protective Effects of NRF2, an Anti-oxidative Stress Transcription Factor, against Radiation-induced Oncogenesis and Mutagenesis
2019 - 2022 A new oligonucleotide treatment with CRISPR/Cas13 using model mice of spinocerebellar ataxia.
2016 - 2019 Analysis of pathological mechanism of spinocerebellar ataxia using differentiated cerebellar cells derived from iPS cells and model mouse.
2014 - 2016 The mechanism of neuronal cell death induced by a new mutation of peroxisomal enzyme via the mitochondorial disfunction

Papers (32)：

Kodai Kume, Takashi Kurashige, Keiko Muguruma, Hiroyuki Morino, Yui Tada, Mai Kikumoto, Tatsuo Miyamoto, Silvia Natsuko Akutsu, Yukiko Matsuda, Shinya Matsuura, et al. CGG repeat expansion in LRP12 in amyotrophic lateral sclerosis. American journal of human genetics. 2023. 110. 7. 1086-1097
Yukiko Matsuda, Arikuni Uchimura, Yasunari Satoh, Naohiro Kato, Masaaki Toshishige, Junko Kajimura, Kanya Hamasaki, Kengo Yoshida, Tomonori Hayashi, Asao Noda, et al. Spectra and characteristics of somatic mutations induced by ionizing radiation in hematopoietic stem cells. Proceedings of the National Academy of Sciences. 2023. 120. 15
Kengo Yoshida, Yasunari Satoh, Arikuni Uchimura, Munechika Misumi, Seishi Kyoizumi, Masataka Taga, Yukiko Matsuda, Asao Noda, Yoichiro Kusunoki. Massive expansion of multiple clones in the mouse hematopoietic system long after whole-body X-irradiation. Scientific Reports. 2022. 12. 1
Toshinori Matsuoka, Miwako Yamasaki, Manabu Abe, Yukiko Matsuda, Hiroyuki Morino, Hideshi Kawakami, Kenji Sakimura, Masahiko Watanabe, Kouichi Hashimoto. Kv11 (ether-à-go-go-related gene) voltage-dependent K+ channels promote resonance and oscillation of subthreshold membrane potentials. The Journal of physiology. 2021. 599. 2. 547-569
Naoyuki Hara, Hiroyuki Morino, Yukiko Matsuda, Kenichi Satoh, Kouichi Hashimoto, Hirofumi Maruyama, Hideshi Kawakami. Zonisamide can ameliorate the voltage-dependence alteration of the T-type calcium channel CaV3.1 caused by a mutation responsible for spinocerebellar ataxia. Molecular Brain. 2020. 13. 1

ｍore...

MISC (5)：

森野豊之, 松田由喜子, 倉重毅志, 川上秀史. ゲノム編集技術が切り拓く神経内科学 CRISPR/Cas9を用いたSCA42モデルマウスの作製と解析. 臨床神経学. 2019. 59. Suppl. S81-S81
森野豊之, 久米広大, 小牟禮修, 松田由喜子, 倉重毅志, 川上秀史. SCAR8の原因遺伝子SYNE1のC末側変異と運動ニューロン疾患の関連. 日本人類遺伝学会大会プログラム・抄録集. 2019. 64th
森野豊之, 松田由喜子, 倉重毅志, 六車恵子, 外丸祐介, 橋本浩一, 丸山博文, 川上秀史. SCA42の臨床と分子病態機序. 神経治療学(Web). 2017. 34. 6. S111(J-STAGE)
森野豊之, 松田由喜子, 倉重毅志, 六車恵子, 外丸祐介, 橋本浩一, 丸山博文, 川上秀史. SCA42の臨床と分子病態機序. 神経治療. 2017. 34. 6. S111-S111
KAWAKAMI HIDESHI, MORINO TOYOYUKI, MATSUDA YUKIKO, OSAWA RYOSUKE, HIRAKI KEIKO, KURASHIGE TSUYOSHI, IZUMI YUISHIN, YAMASAKI YU, TAKAHASHI TETSUYA, TAKASHIMA AKIHIKO, et al. TDP-17の原因遺伝子MAPTの新規挿入変異の同定と生化学解析. 日本生物学的精神医学会誌. 2014. 266

Professional career (1)：

博士(医学) (大阪大学)

Work history (6)：

2021/04 - 現在 Hiroshima University Research Institute for Radiation Biology and Medicine Visiting Associate Professor
2019/11 - 現在 Radiation Effects Research Foundation Department of Molecular Biosciences (Concurrently assigned to the Biosample Research Center) Research Scientist
2019/04 - 2021/03 Hiroshima University Research Institute for Radiation Biology and Medicine Researcher
2016/04 - 2019/03 Hiroshima University Research Institute for Radiation Biology and Medicine Research Fellow, Japan Society for the Promotion of Science
2015/04 - 2016/03 Hiroshima University Research Institute for Radiation Biology and Medicine Researcher

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