Masanori Obana

オバナマサノリ | Masanori Obana

Affiliation and department：
Other affiliations (3)：

Osaka University
Osaka University
Osaka University

Research field (1)： Nephrology

Research theme for competitive and other funds (4)：

2020 - 2022 Identification and characterization of novel myeloid cells that infiltrate into post-infarct myocardium
2018 - 2021 The development of therapeutic strategies for chronic kidney disease targeting the transcription factor OASIS in podocytes
2018 - 2021 Molecular mechanisms of cell proliferation of adult mammalian cardiomyocytes
2015 - 2018 The role of MALAT1 in the pathogenesis of chronic kidney disease

Papers (42)：

Hibiki Sakai, Hiroyasu Kamuro, Nagisa Tokunoh, Takeshi Izawa, Shigeyuki Tamiya, Ayaha Yamamoto, Shota Tanaka, Daisuke Okuzaki, Chikako Ono, Yoshiharu Matsuura, et al. JAK inhibition during the early phase of SARS-CoV-2 infection worsens kidney injury by suppressing endogenous antiviral activity in mice. American journal of physiology. Renal physiology. 2024
Tomoki Sakata, Hiroki Kohno, Tomohiko Inui, Hiroki Ikeuchi, Yuki Shiko, Yohei Kawasaki, Shota Suzuki, Shota Tanaka, Masanori Obana, Kiyotake Ishikawa, et al. Cardioprotective effect of Interleukin-11 against warm ischemia-reperfusion injury in a rat heart donor model. European journal of pharmacology. 2023. 961. 176145-176145
Shota Suzuki, Shota Tanaka, Yusuke Kametani, Ayaka Umeda, Kosuke Nishinaka, Kaho Egawa, Yoshiaki Okada, Masanori Obana, Yasushi Fujio. Runx1 is upregulated by STAT3 and promotes proliferation of neonatal rat cardiomyocytes. Physiological reports. 2023. 11. 23. e15872
Maaya Morita, Aki Yoneda, Nagisa Tokunoh, Tatsumi Masaki, Keisuke Shirakura, Mayumi Kinoshita, Rina Hashimoto, Naoya Shigesada, Junya Takahashi, Masashi Tachibana, et al. Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 3. e2213317120
Koki Tanaka, Hiroki Harada, Hiroyasu Kamuro, Hibiki Sakai, Ayaha Yamamoto, Masashi Tomimatsu, Akari Ikeda, Renya Chosokabe, Shota Tanaka, Yoshiaki Okada, et al. Arid5a/IL-6/PAI-1 Signaling Is Involved in the Pathogenesis of Lipopolysaccharide-Induced Kidney Injury. Biological & pharmaceutical bulletin. 2023. 46. 12. 1753-1760

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MISC (86)：

Wada Yuriko, Kametani Yusuke, Suzuki Shota, Umeda Ayaka, Nishinaka Kosuke, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Obana Masanori, Fujio Yasushi. Exhaustive exploration of novel factors related to cardiomyocyte proliferation using the cell cycle-sensitive protein FUCCI. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 95. 2-O-099
Kametani Yusuke, Suzuki Shota, Umeda Ayaka, Nishinaka Kosuke, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Obana Masanori, Fujio Yasushi. Endogenous YAP activity potentiates GSK3 inhibitors-induced proliferation of cardiomyocytes. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 95. 1-YIA-19
Miyake Yoshiaki, Obana Masanori, Yamamoto Ayaha, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Imaizumi Kazunori, Asanuma Katsuhiko, Fujio Yasushi. Increased OASIS in podocytes contributes to the disruption of kidney homeostasis. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 95. 1-YIA-23
Sayuri Mitsuoka, Obana Masanori, Miyake Yoshiaki, Yamamoto Ayaha, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Fujio Yasushi. IL-6 family cytokines, STAT3 activators, exhibit differential effects in a ligand-specific manner in podocytes. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 95. 1-O-010
Tomimatsu Masashi, Yokota Kosei, Kominami Shunsuke, Tanaka Shota, Maeda Makiko, Okada Yoshiaki, Obana Masanori, Fujio Yasushi. TGFβ3 exacerbates myocardial remodeling after myocardial infarction. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 95. 1-O-036

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Books (2)：

ベーシック薬学教科書シリーズ19 薬物治療学(第2版)
化学同人 2019 ISBN:9784759816297
循環器内科
科学評論社 2010

Lectures and oral presentations (5)：

ポドサイトにおける転写因子Old Astrocyte Specifically Induced Substance(OASIS)の欠損は、Protein Kinase C Iotaを介してLPSによる尿細管傷害を抑制する
(第30回循環薬理学会 2020)
転写因子Old Astrocyte Specifically Induced Substance(OASIS)は新規腎線維化制御因子である.
(第29回日本循環薬理学会第55回高血圧関連疾患モデル学会合同学会 2019)
Suppression of transcription factor OASIS ameliorated kidney fibrosis.
(ASN Kidney Week 2019 Annual Meeting 2019)
転写因子を標的とした慢性腎臓病治療法の開発を目指して.
(第 11 回北陸合同バイオシンポジウム 2018)
転写因子OASISは筋線維芽細胞の増殖,遊走を介して腎線維化に関与する
(日本腎臓学会学術集会 2018)

Professional career (1)：

博士(臨床薬学) (大阪大学)

Work history (7)：

2022/08 - 現在 Osaka University
2021/01 - 現在 Osaka University Global Center for Medical Engineering and Informatics
2020/09 - 現在 Osaka University
2020/04 - 現在大阪大学大学院薬学研究科
2018/04 - 現在 Osaka University

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Committee career (6)：

2020/04 - 現在日本薬理学会評議員
2019/08 - 現在日本薬学会薬理系薬学部会若手世話人
2022/03 - 2022/12 第96回日本薬理学会年会プログラム委員
2018/04 - 2020/03 日本腎臓学会基礎研究推進小委員会委員
大阪大学大学院薬学研究科X線作業主任者

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Awards (4)：

2023/08 - 日本薬学会薬理系薬学部会生体機能と創薬シンポジウム2023優秀発表賞
2023/03 - 令和4年度大阪大学沢井記念薬友会賞研究部門賞
2019/11 - 第29回日本循環薬理学会第55回高血圧関連疾患モデル学会合同学会優秀演題賞転写因子Old Astrocyte Specifically Induced Substance(OASIS)は新規腎線維化制御因子である.
2019/11 - 第29回日本循環薬理学会 Young Investigator Award 転写因子Old Astrocyte Specifically Induced Substance(OASIS)は新規腎線維化制御因子である.

Association Membership(s) (4)：

日本薬理学会 , 日本循環薬理学会 , 日本腎臓学会 , 日本薬学会

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