TAKU MURATA

Research field (1)： Surgical dentistry

Research keywords (3)： Oral and Maxillofacial Surgery , Phosphodiesterase , MRONJ

Research theme for competitive and other funds (18)：

2022 - 2025 A new treatment for malignant melanoma based on the concept of compartmentalization of cAMP-PDE2 signal transduction
2021 - 2024 PDE1を分子標的とした口腔悪性黒色腫新規治療法の開発
2018 - 2021 Studies for clinical application of PDE1 inhibitors to the treatment of malignant melanoma
2018 - 2021 Search for novel personalized therapies targeting the PDE2 intracellular signaling complex in malignancies
2015 - 2018 Elucidation of metastasis regulation mechanism of oral malignant melanoma by phosphodiesterase 1 inhibitor for novel therapeutic method

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Papers (50)：

Gaku Koizumi, Akinobu Hayashi, Akira Takigawa, Rina Yamada, Taku Murata, Kasumi Shimizu, Masatoshi Watanabe, Naoya Arai. Novel Histopathological Findings of Micro Bone Fragments and Epithelial Response in the Oral Mucosa in Bisphosphonate-Related Osteonecrosis of the Jaw. Journal of Investigative Medicine High Impact Case Reports. 2024. 12
Kazuto Kurohara, Kasumi Shimizu, Taku Murata, Gaku Koizumi, Akira Takigawa, Kokoro Nagata, Kenya Okumura, Naoya Arai. Predictive Value of Neutrophil-Lymphocyte Ratio as a Marker in Antiresorptive Agent-Related Osteonecrosis of the Jaw: A Retrospective Analysis. Diagnostics. 2022. 12. 8. 1836-1836
Murata T, Shimizu K, Kurohara K, Tomeoku A, Koizumi G, Arai N. Role of Phosphodiesterase2A in Proliferation and Migration of Human Osteosarcoma Cells. Anticancer research. 2019. 39. 11. 6057-6062
Murata T, Kutsuna T, Kurohara K, Shimizu K, Tomeoku A, Arai N. Evaluation of a New Hydroxyapatite Nanoparticle as a Drug Delivery System to Oral Squamous Cell Carcinoma Cells. Anticancer research. 2018. 38. 12. 6715-6720
F. Ahmad, T. Murata, K. Shimizu, E. Degerman, D. Maurice, V. Manganiello. Cyclic Nucleotide Phosphodiesterases: important signaling modulators and therapeutic targets. ORAL DISEASES. 2015. 21. 1. E25-E50

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Professional career (1)：

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