Hara Hiromichi

Affiliation and department：

Research field (1)： Respiratory medicine

Research keywords (5)：オートファジー , 細胞老化 , びまん性肺疾患 , 慢性閉塞性肺疾患 , 特発性間質性肺炎

Research theme for competitive and other funds (9)：

2022 - 2025 喫煙による喘息難治化におけるフェロトーシスの役割
2022 - 2025 COPD病態におけるcGAS-STINGの重要性
2020 - 2023 小胞体選択的オートファジーによる特発性肺線維症の病態制御
2019 - 2022 mitochondria UPR in Idiopathic interstitial pneumonia
2016 - 2019 Role of senescent cell removal mechanism in the pathogenesis of idiopathic pulmonary fibrosis

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Papers (146)：

Shota Fujimoto, Yuta Hirano, Naoaki Watanabe, Sachi Matsubayashi, Shun Inukai, Saiko Nishioka, Masahiro Yoshida, Saburo Ito, Shunsuke Minagawa, Hiromichi Hara, et al. Lipogenic Lung Fibroblast-derived Extracellular Vesicles Mitigate Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease Pathologies through LAT1-mediated Alveolar Type II Cell Restoration. 2024
Takanori Numata, Keitaro Okuda, Hanae Miyagawa, Shunsuke Minagawa, Takeo Ishikawa, Hiromichi Hara, Jun Araya. Clinical features in patients with COVID-19 treated with biologics for severe asthma. The journal of allergy and clinical immunology. Global. 2024. 3. 2. 100219-100219
Daisuke Takekosh, Teruhisa Nemoto, Susumu Saito, Yuma Matsui, Shunsuke Minagawa, Hiromichi Hara, Takanori Numata, Jun Araya, Kazuyoshi Kuwano. Minoxidil-induced lung disease, masquerading as hypersensitivity pneumonitis. Respiratory medicine case reports. 2023. 43. 101861-101861
Kyota Shinfuku, Hiromichi Hara, Naoki Takasaka, Takeo Ishikawa, Jun Araya, Kazuyoshi Kuwano. The usefulness of change in CT score for evaluating the activity of Mycobacterium abscessus (Mab) pulmonary disease (Mab-PD). PloS one. 2023. 18. 2. e0281103
Shunsuke Minagawa, Jun Araya, Naoaki Watanabe, Shota Fujimoto, Junko Watanabe, Hiromichi Hara, Takanori Numata, Kazuyoshi Kuwano, Yoshinori Matsuwaki. Real-life effectiveness of dupilumab in patients with mild to moderate bronchial asthma comorbid with CRSwNP. BMC Pulmonary Medicine. 2022. 22. 1. 258-258

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MISC (115)：

松林沙知, 保坂悠介, 伊藤三郎, 荒屋潤, 平野悠太, 藤本祥太, 川本浩徳, 渡邉直昭, 藤田雄, 竹越大輔, et al. Senotherapuetic approach with autophagy-lysosome regulation in COPD pathogenesis. 日本呼吸器学会誌(Web). 2023. 12
山田尭徳, 内海裕文, 山田千枝里, 根本暉久, 内山翔太, 齊藤晋, 奥田慶太郎, 渡部淳子, 高橋直子, 宮川英恵, et al. PD-1/PD-L1阻害薬無効後のイピリムマブ+ニボルマブによる免疫チェックポイント阻害薬再投与についての検討. 日本肺癌学会学術集会号. 2022. 63rd (CD-ROM)
Yusuke Hosaka, Jun Araya, Yu Fujita, Kazuya Tsubouchi, Tsukasa Kadota, Masahiro Yoshida, Shunsuke Minagawa, Hiromichi Hara, Hironori Kawamoto, Naoaki Watanabe, et al. Nrf2-regulated chaperon-mediated autophagy is involved in apoptosis modulation in COPD pathogenesis. EUROPEAN RESPIRATORY JOURNAL. 2020. 56
Akihiko Ito, Mitsuo Hashimoto, Jun Tanihata, Hironori Kawamoto, Yusuke Hosaka, Akihiro Ichikawa, Tsukasa Kadota, Yu Fujita, Shunsuke Minagawa, Takanori Numata, et al. Involvement of Parkin-mediated mitophagy in COPD-related sarcopenia pathogenesis. EUROPEAN RESPIRATORY JOURNAL. 2020. 56
皆川俊介, 吉田昌弘, 原弘道, 荒屋潤, 桑野和善. 喫煙誘導性フェロトーシスのCOPD病態への関与. 日本鉄バイオサイエンス学会学術集会プログラム・抄録集. 2020. 44th

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Awards (4)：

2014/09 - 慈恵医師会研究奨励賞
2011/11 - 第15回東京病態研究会奨励賞
2010/11 - 第19回Pneumo Forum賞
2008/10 - 15th International Symposium on Hepatitis C Virus and related viruses Travel Award

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