Iemura Kenji

イエムラケンジ | Iemura Kenji

Affiliation and department：
Job title： Assistant Professor

Research field (4)： Tumor biology , Genetics , Cell biology , Molecular biology

Research keywords (7)： Chromosomal instability , Cell devision , Cancer , Cell cycle , Mitosis , Chromosome , Chromosome segregation

Research theme for competitive and other funds (11)：

2021 - 2024 Elucidation of the mechanism of cell-to-cell transmission of chromosomal instability
2021 - 2022 染色体不安定性がん細胞の増殖優位性獲得機構を抑制する薬理活性化合物の探索
2020 - 2022 Elucidation of the molecular mechanism required for the acquisition of growth advantage in CIN cancer cell
2021 - 2022 細胞の老化に伴って引き起こされる染色体不安定性誘導機構の解明
2018 - 2020 がんのヘテロジェナイエティ構築における染色体不安定性の寄与の解明

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Papers (18)：

Guan Chen, Zhenhua Li, Kenji Iemura, Kozo Tanaka. Oxidative stress induces chromosomal instability through replication stress in fibroblasts from aged mice. Journal of cell science. 2023. 136. 11
Norihisa Shindo, Kazuki Kumada, Kenji Iemura, Jun Yasuda, Haruna Fujimori, Mai Mochizuki, Keiichi Tamai, Kozo Tanaka, Toru Hirota. Autocleavage of separase suppresses its premature activation by promoting binding to cyclin B1. Cell reports. 2022. 41. 9. 111723-111723
Masayoshi Nagai, Kenji Iemura, Takako Kikkawa, Sharmin Naher, Satoko Hattori, Hideo Hagihara, Koh ichi Nagata, Hayato Anzawa, Risa Kugisaki, Hideki Wanibuchi, et al. Deficiency of CHAMP1, a gene related to intellectual disability, causes impaired neuronal development and a mild behavioral phenotype. Brain Communications. 2022. 4. 5
Kenji Iemura, Hayato Anzawa, Ryo Funayama, Runa Iwakami, Keiko Nakayama, Kengo Kinoshita, Kozo Tanaka. High levels of chromosomal instability facilitate the tumor growth and sphere formation. Cancer science. 2022
Chihiro Yamada, Aya Morooka, Seira Miyazaki, Masayoshi Nagai, Satoru Mase, Kenji Iemura, Most Naoshia Tasnin, Tsuneyuki Takuma, Shotaro Nakamura, Shamsul Morshed, et al. TORC1 inactivation promotes APC/C-dependent mitotic slippage in yeast and human cells. iScience. 2021. 25. 2. 103675-103675

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MISC (47)：

家村顕自, 田中耕三. 染色体不安定性に対するがん細胞の生存戦略(Survival strategies of cancer cells against chromosomal instability). 日本癌学会総会記事. 2022. 81回. J-1033
家村顕自, 田中耕三. 染色体分配における染色体オシレーションの役割. 生化学. 2022. 94. 3. 433-437
家村顕自, 田中耕三. Mitotic chromosome oscillation maintains chromosomal stability. 日本細胞生物学会大会(Web). 2021. 73rd
家村顕自, 田中耕三. 分裂期染色体動態異常を介した染色体不安定性の発生機構. 日本癌学会学術総会抄録集(Web). 2021. 80th
家村顕自, 田中耕三. Chromosome oscillation-mediated robust equal segregation system is suppressed together with progression of cellular senescence. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th

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Education (2)：

2009 - 2012 The University of Tokyo Graduate schools of Science
2007 - 2009 Nagahama Institute of Bio-Science and Technology Graduate schools of Bioscience

Professional career (1)：

Work history (6)：

2024/02 - 現在 Tohoku University
2016/02 - 現在 Tohoku University Institute of Development, Aging and Cancer Division of Cancer Control
2012/08 - 2016/01 Institute of Development, Aging and Cancer, Tohoku University
2012/05 - 2012/07 Institute of Development, Aging and Cancer, Tohoku University
2012/04 - 2012/05 The Institute of Medical Science, The University of Tokyo

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Committee career (1)：

Awards (5)：

Association Membership(s) (4)：

日本生化学会 , 日本細胞生物学会 , 日本癌学会 , 日本分子生物学会

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