Rchr
J-GLOBAL ID：201801009059541884
Update date: Oct. 11, 2024
Kobashigawa Shinko
コバシガワ シンコ | Kobashigawa Shinko
Affiliation and department：
Research field (1)：
Cell biology
Research keywords (5)：
cellular senescence
, genomic instability
, mitochondrial fission
, Oxidative stress
, Radiation biology
Research theme for competitive and other funds (7)：
Papers (18)：
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Genro Kashino, Shinko Kobashigawa, Aoki Uchikoshi, Yuki Tamari. VEGF affects mitochondrial ROS generation in glioma cells and acts as a radioresistance factor. Radiation and Environmental Biophysics. 2023. 62. 2. 213-220
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Tomo Shiota, Riko Nagata, Sotaro Kikuchi, Hitoki Nanaura, Masaya Matsubayashi, Mari Nakanishi, Shinko Kobashigawa, Noriyoshi Isozumi, Takao Kiriyama, Kazuaki Nagayama, et al. C9orf72-Derived Proline:Arginine Poly-Dipeptides Modulate Cytoskeleton and Mechanical Stress Response. Frontiers in Cell and Developmental Biology. 2022. 10
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Shinko Kobashigawa, Genro Kashino. Mechanism of ATM activation by radiation. Radiation Biology Research Communications. 2022. 57. 1. 50-62
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Naoki Iwasa, Takeshi K. Matsui, Naohiko Iguchi, Kaoru Kinugawa, Naritaka Morikawa, Yoshihiko M. Sakaguchi, Tomo Shiota, Shinko Kobashigawa, Mari Nakanishi, Masaya Matsubayashi, et al. Gene Expression Profiles of Human Cerebral Organoids Identify PPAR Pathway and PKM2 as Key Markers for Oxygen-Glucose Deprivation and Reoxygenation. Frontiers in Cellular Neuroscience. 2021. 15. 605030-605030
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Masaya Matsubayashi, Yoshihiko M. Sakaguchi, Yoshiki Sahara, Hitoki Nanaura, Sotaro Kikuchi, Arvand Asghari, Linh Bui, Shinko Kobashigawa, Mari Nakanishi, Riko Nagata, et al. 27-Hydroxycholesterol regulates human SLC22A12 gene expression through estrogen receptor action. The FASEB Journal. 2021. 35. 1. e21262
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MISC (3)：
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Genro Kashino, Shinko Kobashigawa. Radioprotective effect by targeting for delayed mitochondrial ROS. Medical Science Digest. 2021. 47. 625. 34-35
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山本 哲彰, 菓子野 元郎, 小橋川 新子, 阿部 史佳, 河野 辰行, 高橋 喜浩, 河野 憲司. 臨床的放射線耐性口腔扁平上皮癌細胞の樹立とその解析. 日本口腔科学会雑誌. 2016. 65. 2. 119-119
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菓子野元郎, 小橋川新子, 玉利勇樹, 森宣. 培養上清成分による放射線感受性の変化. 放射線ワークショップ講演論文集. 2015. 1st
Lectures and oral presentations (25)：
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Involvement of mitochondrial ROS on DNA damage response through ATM activation after irradiation
(The 67th Annual Meeting of Japanese Radiation Research Society 2024)
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Mechanism of radiation-induced mutagenesis through the mitochondrial ROS generation
(The 66th Annual Meeting of Japanese Radiation Research Society 2023)
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Mitochondria-derived ROS sustain ATM activation and participate in radiation-induced cellular senescence
(The 19th Ataxia-Telangiectasia workshop (ATW2023Kyoto) 2023)
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Involvement mechanism of mitochondrial-derived delayed reactive oxygen species as a protective target for normal cells in radiotherapy
(2023)
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Contribution to delayed ROS generation and induction of cellular senescence by carbon beam irradiation
(2022)
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Education (3)：
- 2008 - 2012 Nagasaki University Graduate School of Biomedical Sciences Department of Radiation Medical Sciences
- 2006 - 2008 Kyoto University Graduate School of Science Biological Science
- 2002 - 2006 Nagasaki University School of Pharmaceutical Sciences Pharmaceutical Sciences
Professional career (1)：
Work history (5)：
- 2020/11 - 現在 Nara Medical University Radioisotope Research Center (Applied Medical Science and Clinical Research) Research fellow
- 2019/04 - 2020/10 Nara Medical University Department of Future Basic Medicine Postdoctoral researcher
- 2017/04 - 2019/03 Kyoto University Institute for Integrated Radiation and Nuclear Science Research fellow
- 2012/04 - 2017/03 Oita University Department of Radiology Research associate
- 2008/04 - 2012/03 Nagasaki University Graduate School of Biomedical Sciences Atomic Bomb Disease Institute Ph.D. student
Awards (3)：
- 2012 - Oita University 3rd woman researcher prize for encouragement
- 2011/04 - Nagasaki University Graduate School of Biomedical Sciences Special study scholarship for Ph.D. student
- 2010/10 - Nagasaki University Graduate School of Biomedical Sciences Special study scholarship for Ph.D. student
Association Membership(s) (2)：
JAPANESE SOCIETY FOR RADIATION ONCOLOGY
, THE JAPANESE RADIATION RESEARCH SOCIETY
