Rchr
J-GLOBAL ID：201801009362327224   Update date: Apr. 03, 2024

COBAN Cevayir

COBAN Cevayir
Affiliation and department：
The Institute of Medical Science (IMSUT), The University of Tokyo Department of Microbiology and Immunology, Division of Malaria Immunology

About The Institute of Medical Science (IMSUT), The University of Tokyo Department of Microbiology and Immunology, Division of Malaria Immunology


Job title： Professor
Other affiliations (1)：
  • Osaka University, IFReC  Guest Professor
Homepage URL  (1)： https://www.ims.u-tokyo.ac.jp/malimmun/
Research field  (1)： Immunology
Research keywords  (4)： Host-microbe interactions ,  Malaria ,  Parasitology ,  Immunology
Research theme for competitive and other funds  (5)：
  • 2017 - 2019 マラリアにおける細胞外トラップ
  • 2016 - 2019 Molecular mechanisms of bone-specific immunopathology during malaria
  • 2014 - 2017 A comparative study of intrinsic factor activating inflammasome between Turkey and Japan
  • 2013 - 2016 4D imaging of brain and the immune system during cerebral malaria
  • 2008 - 2009 Innate immune regulation by malaria parasites
Papers (87)：
  • Burcu Temizoz, Takayuki Shibahara, Kou Hioki, Tomoya Hayashi, Kouji Kobiyama, Michelle Sue Jann Lee, Naz Surucu, Erdal Sag, Atsushi Kumanogoh, Masahiro Yamamoto, et al. 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a partial STING agonist, competes for human STING activation. Frontiers in immunology. 2024. 15. 1353336-1353336
  • Burcu Temizoz, Kou Hioki, Shingo Kobari, Nao Jounai, Takato Kusakabe, Michelle S J Lee, Cevayir Coban, Etsushi Kuroda, Ken J Ishii. Anti-tumor immunity by transcriptional synergy between TLR9 and STING activation. International immunology. 2022
  • Michelle S J Lee, Takeshi Inoue, Wataru Ise, Julia Matsuo-Dapaah, James B Wing, Burcu Temizoz, Kouji Kobiyama, Tomoya Hayashi, Ashwini Patil, Shimon Sakaguchi, et al. B cell-intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice. The Journal of experimental medicine. 2022. 219. 2
  • Kou Hioki, Tomoya Hayashi, Yayoi Natsume-Kitatani, Kouji Kobiyama, Burcu Temizoz, Hideo Negishi, Hitomi Kawakami, Hiroyuki Fuchino, Etsushi Kuroda, Cevayir Coban, et al. Machine Learning-Assisted Screening of Herbal Medicine Extracts as Vaccine Adjuvants. Frontiers in immunology. 2022. 13. 847616-847616
  • Fabian A Fischer, Linda F M Mies, Sohaib Nizami, Eirini Pantazi, Sara Danielli, Benjamin Demarco, Michael Ohlmeyer, Michelle Sue Jann Lee, Cevayir Coban, Jonathan C Kagan, et al. TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation. Proceedings of the National Academy of Sciences of the United States of America. 2021. 118. 38
ｍore...
MISC (6)：
  • Cevayir Coban, Miyuki Tozuka, Nao Jounai, Kouji Kobiyama, Fumihiko Takeshita, Choon Kit Tang, Choon Kit Tang, Choon Kit Tang, Ken J. Ishii, Ken J. Ishii. DNA Vaccine: Does it Target the Double Stranded-DNA Sensing Pathway?. Biological DNA Sensor: The Impact of Nucleic Acids on Diseases and Vaccinology. 2013. 257-270
  • Innate and adaptive immune responses to DNA vaccine. 2008. 227. 5. 387-392
  • Pathological role of TLR in cerebral malaria. Clinical immunology & allergology. 2008. 49. 3. 265-273
  • Adjuvant for virus vaccine. Virus report. 2008. 5. 1. 74-81
  • Sugiyama, T., Gursel, M., Takeshita, F., Coban, C., Conover, J., Kaisho, T., Akira, S., Klinman, D.M., Ishii, K.J. Erratum: CpG RNA: Identification of novel single-stranded RNA that stimulates human CD14+CD11c+ monocytes (Journal of Immunology (2005) 174 (2273-2279)). Journal of Immunology. 2005. 175. 3. 2026
ｍore...
Professional career (2)：
  • MD (Hacettepe University School of Medicine)
  • Clinical Microbiology (Ankara Numune Education and Research Hospital (Current name: Ankara City Hospital of University of Health Sciences)
Work history (5)：
  • 2019 - 現在 The Institute of Medical Science (IMSUT), The University of Tokyo Division of Malaria Immunology Professor
  • 2015 - 2020 Osaka University, Immunology Frontier Research Center Laboratory of Malaria Immunology Professor
  • 2010 - 2015 Osaka University, Immunology Frontier Research Center Laboratory of Malaria Immunology Associate Professor
  • 2003 - 2009 Osaka University Department of Host Defense Assistant Professor/ Postdoc
  • 2000 - 2003 Johns Hopkins University, School of Public Health Malaria Research Institute Postdoctoral Fellow
Awards (1)：
  • 2017 - Japanese Society of Immunology Women Immunologist Award
Association Membership(s) (4)：
Turkish Society of Immunology ,  American Association of Immunologist ,  Japanese Society for Parasitology ,  Japanese Society of Immunology
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