Rchr
J-GLOBAL ID：201801009421857151   Update date: Mar. 20, 2024

KOUICHI OZAKI

オザキコウイチ | KOUICHI OZAKI
Affiliation and department：
Research Institute, National Center for Geriatrics and Gerontology Department of Genomic Medicine, Medical Genome Center

About Research Institute, National Center for Geriatrics and Gerontology Department of Genomic Medicine, Medical Genome Center


Other affiliations (2)：
Homepage URL  (1)： https://www.ncgg.go.jp/ri/lab/mgc/department/genome/home.html
Research keywords  (2)： Medical genetics ,  Genomic medicine
Research theme for competitive and other funds  (9)：
  • 2021 - 2026 Development of a prognosis prediction model for Alzheimer's disease using integrative multi-omics data
  • 2022 - 2025 Elucidation of pathophysiology of non-pulmonary artery-derived atrial fibrillation based on genomic information and application to optimal treatment
  • 2021 - 2024 Elucidation of genetic factors that define myocardial vulnerability as a basis for the development of heart failure
  • 2018 - 2023 Establishment of a novel strategy for pathological analysis of multifactorial diseases using genetic risk variants
  • 2018 - 2021 Identification of the genes for mechanical stress diseases
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Papers (88)：
  • Mutsumi Suganuma, Motoki Furutani, Tohru Hosoyama, Risa Mitsumori, Rei Otsuka, Marie Takemura, Yasumoto Matsui, Yukiko Nakano, Shumpei Niida, Kouichi Ozaki, et al. Identification of potential blood-based biomarkers for frailty by using an integrative approach. Gerontology. 2024
  • Yuya Asanomi, Tetsuaki Kimura, Nobuyoshi Shimoda, Daichi Shigemizu, Shumpei Niida, Kouichi Ozaki. CRISPR/Cas9-mediated knock-in cells of the late-onset Alzheimer's disease-risk variant, SHARPIN G186R, reveal reduced NF-κB pathway and accelerated Aβ secretion. Journal of human genetics. 2024
  • Daichi Shigemizu, Koya Fukunaga, Akiko Yamakawa, Mutsumi Suganuma, Kosuke Fujita, Tetsuaki Kimura, Ken Watanabe, Taisei Mushiroda, Takashi Sakurai, Shumpei Niida, et al. The HLA-DRB1*09:01-DQB1*03:03 haplotype is associated with the risk for late-onset Alzheimer's disease in APOE [Formula: see text]4-negative Japanese adults. npj aging. 2024. 10. 1. 3-3
  • Yann Le Guen, Guo Luo, Aditya Ambati, Vincent Damotte, Iris Jansen, Eric Yu, Aude Nicolas, Itziar de Rojas, Thiago Peixoto Leal, Akinori Miyashita, et al. Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes. Proceedings of the National Academy of Sciences. 2023. 120. 36
  • Daichi Shigemizu, Shintaro Akiyama, Mutsumi Suganuma, Motoki Furutani, Akiko Yamakawa, Yukiko Nakano, Kouichi Ozaki, Shumpei Niida. Classification and deep-learning-based prediction of Alzheimer disease subtypes by using genomic data. Translational psychiatry. 2023. 13. 1. 232-232
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MISC (39)：
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Professional career (1)：
  • 博士(医学) (大阪大学)
Work history (7)：
  • 2021/04 - 現在 Research Institute, National Center for Geriatrics and Gerontology Department of Genomic Medicine, Medical Genome Center Professor
  • 2016/09 - 2021/03 National Center for Geriatrics and Gerontology Division for Genomic Medicine Head
  • 2013/04 - 2016/08 理化学研究所 統合生命医科学研究センター 上級研究員
  • 2008/04 - 2013/03 理化学研究所 ゲノム医科学研究センター 上級研究員
  • 2005/04 - 2008/03 理化学研究所 遺伝子多型研究センター 上級研究員
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Awards (1)：
  • 2010/02 - 循環器研究振興基金賞(内田賞)
Association Membership(s) (3)：
American Society for Human Genetics ,  The Japanese Circulation Society ,  THE JAPAN SOCIETY OF HUMAN GENETICS
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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