Juntendo University
Division of Glycobiologics, School of Medicine
Assistant Professor (part time)
Research theme for competitive and other funds (4)：
2021 - 2024 The importance of NGLY1 on the chemoresistance of triple negative breast cancer
2021 - 2024 肺癌における糖鎖分子を標的としたEGFR-TKI耐性克服の試み
2018 - 2020 Revealing a role of cytoplasmic de-glycosylation in the erythropoiesis
2016 - 2018 Revealing the physiological function of de-N-glycosylating enzymes in mice
Papers (24)：
Haruhiko Fujihira, Keiko Sato, Yuji Nishiuchi, Takefumi Murase, Yuka Matsuda, Yukiko Yoshida, Takayuki Kamei, Tadashi Suzuki. ELISA-based highly sensitive assay system for the detection of endogenous NGLY1 activity. Biochemical and biophysical research communications. 2024. 710. 149826-149826
Tadashi Suzuki, Haruhiko Fujihira. NGLY1: A fascinating, multifunctional molecule. Biochimica et biophysica acta. General subjects. 2024. 1868. 2. 130379-130379
Chengcheng Huang, Junichi Seino, Akinobu Honda, Haruhiko Fujihira, Di Wu, Kyohei Okahara, Shinobu Kitazume, Shuichi Nakaya, Ken Kitajima, Chihiro Sato, et al. Rat hepatocytes secrete free oligosaccharides. The Journal of biological chemistry. 2024. 300. 3. 105712-105712
Yoshiya Horimoto, May Thinzar Hlaing, Harumi Saeki, Kaori Denda-Nagai, Katrin Ishii-Schrade, Haruhiko Fujihira, Masaaki Abe, Miki Noji, Shigeyuki Shichino, Mitsue Saito, et al. Glycosylation profiles of breast cancer cells may represent clonal variations of multiple organ metastases. Clinical & experimental metastasis. 2024
Ryoko Semba, Yoshiya Horimoto, Madoka Sakata-Matsuzawa, Yumiko Ishizuka, Kaori Denda-Nagai, Haruhiko Fujihira, Miki Noji, Hiroko Onagi, Miyu Ichida, Hiroyoshi Miura, et al. Possible correlation of apical localization of MUC1 glycoprotein with luminal A-like status of breast cancer. Scientific reports. 2023. 13. 1. 5281-5281
Yayoi Yoshimura, Takahiko Matsushita, Naoki Fujitani, Fujihira Haruhiko, Yasuhiro Takegawa, Naomi Manri, Akihito Kaneko, Takeshi Sakamoto, Xiao-Dong Gao, Hiroshi Hinou, et al. Chemo-enzymatic synthesis of mucin-type glycopeptides using sugar-protective groups and ppGalNAcT-2. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2010. 239
Awards (2)：
2023/09 - The Japanese Society for Carbohydrate Research Incentive Award
