Hashimoto Muneaki

Affiliation and department：

Research field (1)： Parasitology

Research keywords (4)：アフリカ , フィールドワーク , 診断機器開発 , マラリア

Research theme for competitive and other funds (11)：

2019 - 2023 マラリア排除のための全自動診断装置の高機能化
2012 - 2016 Host and tissue specificity of Trypanosoma cruzi in the wild reservoirs
2005 - 2007 TRYPANASOMAGRUZI : MOLECULAR BASES FOR INTRACELLULAR PARASITISM, PROLIFERATION, AND PATHOGENICITY IN INFECTED HUMAN CELLS
Mechanism of inhibition of apoptosis in ┣DBTrypanosoma(/)-┫DB ┣DBcruzi(/)-┫DB-infected host cells and target molecules in the signaling pathway.
クルーズトリパノソーマ感染細胞におけるアポトーシス抑制機構の解析および標的分子の探索

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Papers (62)：

Kazumichi Yokota, Asae Takeo, Hiroko Abe, Yuji Kurokawa, Muneaki Hashimoto, Kazuaki Kajimoto, Masato Tanaka, Sanae Murayama, Yoshihiro Nakajima, Masateru Taniguchi, et al. Application of Micropore Device for Accurate, Easy, and Rapid Discrimination of Saccharomyces pastorianus from Dekkera spp. Biosensors. 2021. 11. 8
Fariz Nurwidya, Fumiyuki Takahashi, Wira Winardi, Ken Tajima, Yoichiro Mitsuishi, Akiko Murakami, Isao Kobayashi, Takeshi Nara, Muneaki Hashimoto, Motoyasu Kato, et al. Zinc-finger E-box-binding homeobox 1 (ZEB1) plays a crucial role in the maintenance of lung cancer stem cells resistant to gefitinib. Thoracic cancer. 2021. 12. 10. 1536-1548
Naoyuki Fukuda, Shin-Ichiro Tachibana, Mie Ikeda, Miki Sakurai-Yatsushiro, Betty Balikagala, Osbert T Katuro, Masato Yamauchi, Sakurako Emoto, Muneaki Hashimoto, Shouki Yatsushiro, et al. Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in Northern Uganda. Parasitology international. 2021. 81. 102277-102277
Kazumichi Yokota, Muneaki Hashimoto, Kazuaki Kajimoto, Masato Tanaka, Sanae Murayama, Makusu Tsutsui, Yoshihiro Nakajima, Masateru Taniguchi, Masatoshi Kataoka. Effect of Electrolyte Concentration on Cell Sensing by Measuring Ionic Current Waveform through Micropores. Biosensors. 2021. 11. 3. 78-78
Noriko Tamari, Noboru Minakawa, George O. Sonye, Beatrice Awuor, James O. Kongere, Muneaki Hashimoto, Masatoshi Kataoka, Stephen Munga. Protective effects of Olyset® Net on Plasmodium falciparum infection after three years of distribution in western Kenya. Malaria Journal. 2020. 19. 1

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MISC (5)：

橋本宗明, 八代聖基, 山村昌平, 片岡正俊. 細胞チップを用いた迅速高感度マラリア感染症診断法の開発 - 200万分の1の感染を見出しマラリアに立ち向かう -. Synthesiology. 2017. 10. 1
Muneaki Hashimoto, Shouki Yatsushiro, Shohei Yamamura, Masatoshi Kataoka. Development of a cell microarray chip system for early and accurate malaria diagnosis: Finding one parasite in 2 million erythrocytes for elimination of malaria. Synthesiology. 2017. 10. 1. 33-40
Kyoichi Iizumi, Yuko Mikami, Muneaki Hashimoto, Takeshi Nara, Yukichi Hara, Takashi Aoki. Molecular cloning and characterization of ouabain-insensitive Na+-ATPase in the parasitic protist, Trypanosoma cruzi. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 2006. 1758. 6. 738-746
M Hashimoto, J Nakajima-Shimada, T Aoki. Trypanosoma cruzi posttranscriptionally up-regulates and exploits cellular FLIP for inhibition of death-inducing signal. MOLECULAR BIOLOGY OF THE CELL. 2005. 16. 8. 3521-3528
S Takamiya, H Yamasaki, M Hashimoto, H Taka, K Murayama, M Tagaya, T Aoki. Heterologous expression of Ascaris suum cytochrome b(5) precursor protein: a histidine-tagged full-length presequence is correctly processed to transport the mature protein to the periplasm of Escherichia coli. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2003. 413. 2. 253-261

Patents (2)：

プラスチック基材及び血液標本の作製方法
Genetically modified Trypanosoma cruzi having a calcium indicator and use thereof for screening anti-trypanosoma drugs

Education (1)：

2001 - 2005 Juntendo University

Professional career (1)：

(BLANK) (Tokyo University of Pharmacy and Life Science)

Work history (1)：

2016/04 - 現在産業技術総合研究所

Awards (2)：

2017/05 - 第54回山陽放送学術文化財団研究助成学術奨励賞
2012/03 - 第6回日本寄生虫学会大会ベストプレゼンテーション賞

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