Yusuke Suzuki

スズキユウスケ | Yusuke Suzuki

Affiliation and department：

Research field (1)： Nephrology

Research theme for competitive and other funds (23)：

2021 - 2024 IgA腎症において粘膜免疫応答異常から全身展開する糖鎖異常IgA1産生機序の解明

2021 - 2024 IgA腎症における血尿の形態的基盤構築 ~的確で特異的な治療介入促進を目指す~

2020 - 2023 IgA腎症の粘膜応答異常に関与する樹状細胞、B細胞およびT細胞サブセットの解明

2019 - 2022 Elucidation of glycosylation form of nephritogenic IgA1 and dysregulation of mucosal immunity in IgA nephropathy

2017 - 2020 Elucidation of APRIL-mediated immune abnormalities by tonsillar germinal center B cells in the pathogenesis of IgA nephropathy

2017 - 2020 Dysregulation of immune response in murine IgA nephropathy

2015 - 2018 Pathophysiological role of kidney in systemic oxidative stress during chronic intermittent hypoxia.

2015 - 2017 Criteria of tonsillectomy in IgA nephropathy

2014 - 2017 Effects of renal sympathetic nervous and L-FABP on oxidative stress response in the brain

2014 - 2017 Clarification of the disease susceptibility gene in IgA nephrology prone mice

2014 - 2017 Clarification of the role of CX3CR1/FKN/AIM axis in IgA nephrology

2013 - 2016 Renal lipid metabolism in extrarenal vascular injuly

2013 - 2016 The Analysis of aberrant glycosylation of IgA and B cells secreting those IgAs in IgA Nephropathy

2013 - 2015 Aberrant APRIL expression in tonsillar germinal center B cells in IgA nephropathy

2012 - 2014 Development of procine model to establish the specific treatment for IgA nephropathy

2009 - 2011 Approach to the mechanism organ specific homing of responsible cells in IgA nephropathy

2008 - 2010 Potential roles of dendritic cells in murine IgA nephropathy

2006 - 2007 Analysis of IgAl binding protein(BP)in IgA Nephropathy(IgA) patients using Mass Spectrometry(MS)

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Papers (549)：

Mizuki Higashiyama, Kei Haniuda, Yoshihito Nihei, Saiko Kazuno, Mika Kikkawa, Yoshiki Miura, Yusuke Suzuki, Daisuke Kitamura. Oral bacteria induce IgA autoantibodies against a mesangial protein in IgA nephropathy model mice. Life Science Alliance. 2024. 7. 4. e202402588-e202402588
Shinji Hagiwara, Tomohito Gohda, Phillip Kantharidis, Jun Okabe, Maki Murakoshi, Yusuke Suzuki. Potential of Modulating Aldosterone Signaling and Mineralocorticoid Receptor with microRNAs to Attenuate Diabetic Kidney Disease. International journal of molecular sciences. 2024. 25. 2
二瓶義人, 鈴木祐介, 鈴木仁. 【腎臓学この1年の進歩】IgA腎症治療の現在従来治療から最新の分子標的薬まで. 日本腎臓学会誌. 2024. 66. 1. 315-320
Koshi Yamada, Jan Novak, Yusuke Suzuki. GWAS-follow-up Studies Identified a Connection between Abnormal LIF/JAK2/STAT1 Signaling and Overproduction of Galactose-Deficient IgA1 in the Tonsillar IgA1-Secreting Cells from Patients with IgA Nephropathy. Journal of clinical research & bioethics. 2024. 15. 1
Keiichi Matsuzaki, Megumi Kitayama, Keiichi Yamamoto, Rei Aida, Takumi Imai, Mami Ishida, Ritsuko Katafuchi, Tetsuya Kawamura, Takashi Yokoo, Ichiei Narita, et al. A Pragmatic Method to Integrate Data From Preexisting Cohort Studies Using the Clinical Data Interchange Standards Consortium (CDISC) Study Data Tabulation Model: Case Study. JMIR Medical Informatics. 2023. 11. e46725-e46725

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MISC (256)：

中川由紀, 中川由紀, 中川由紀, 三重野牧子, 三重野牧子, 小笠大起, 毎熊政行, 剣持敬, 剣持敬, 湯沢賢治, et al. 長期透析患者における腎移植成績~我が国の腎移植統計から~. 日本透析医学会雑誌. 2023. 56. Supplement 1
毎熊政行, 中川由紀, 木原正夫, 上田誠二, 合田朋仁, 江花耕介, 遠藤亮子, 工藤一恵, 田口南, 小笠大起, et al. 当院の腎移植における腎臓内科医の役割-症例数の増加と高いPEKT率について-. 移植(Web). 2023. 58. 2
廣瀬樹, 田中翔大, 木原正夫, 小林敬, 山田耕嗣, 上田誠二, 合田朋仁, 鈴木祐介. 白質脳症で発症し持続的血液透析濾過(CHDF)が奏功した尿毒症性脳症の一例. 日本腎臓学会誌(Web). 2023. 65. 6-E
山田耕嗣, 鈴木祐介. 血栓・止血の異常を理解する-広くて深い基礎知識[Chapter2]血栓・止血に関連する疾患 C.出血性疾患 IgA血管炎. 内科. 2023. 132. 4
臼井直人, 臼井直人, 上畑昭美, 中田純一郎, 小島将, 小島将, 久留秀樹, 稲津昭仁, 土屋貴彦, 馬渡貴之, et al. 血液透析患者における最大運動後の心拍数回復応答とprotein-energy wastingおよび非心血管入院率の関連. 日本腎臓リハビリテーション学会学術集会プログラム・抄録集. 2023. 13th

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Lectures and oral presentations (159)：

Clinical application of IgA type autoantibodies against mesangial autoantigen, βII-spectrin, in IgA nephropathy
(American Society of Nephrology (ASN2023) 2023)
Investigation of T Cells contributing to the production of IgA-Type autoantibodies against mesangial Cells in IgA nephropathy
(American Society of Nephrology (ASN2023) 2023)
Understanding the role of APRIL in the pathogenesis of IgAN
(the 17th international Symposium on IgA Nephropathy (IIGANN 2023) 2023)
B cell targeting therapy
(the 17th international Symposium on IgA Nephropathy (IIGANN 2023) 2023)
The mechanism for cell-surface expression of beta2-spectrin at mesangial region
(the 17th international Symposium on IgA Nephropathy (IIGANN 2023) 2023)

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