Rchr
J-GLOBAL ID：201801009641251483   Update date: Apr. 17, 2024

NAKAYAMA Takahiro

ナカヤマ タカヒロ | NAKAYAMA Takahiro
Affiliation and department：
Kyorin University School of Medicine

About Kyorin University School of Medicine


Research field  (7)： Cell biology ,  Structural biochemistry ,  Biophysics ,  Molecular biology ,  Neuroscience - general ,  Medical biochemistry ,  Neuropathology
Research keywords  (10)： SNARE ,  Syntaxin ,  Vesicle transport ,  Molecular motility ,  Tubulin dynamics ,  Epigenetics ,  Psychiatric disorder ,  Neurodevelopmental disorder ,  Autism spectrum disorder ,  Attention deficit
Research theme for competitive and other funds  (3)：
  • 2012 - 2015 Functional difference between syntaxin1 isoforms in synaptic transmission
  • 2005 - 2007 膜非結合型シンタキシン1Cの小胞輸送に関わる分子機構の解明とウィリアムス症候群
  • 1999 - 2000 開口放出関連蛋白HPC-1/syntaxin1Aの発現制御とウィリアムス症候群
Papers (13)：
  • Takahiro Nakayama, Akash K. Singh, Toshiyuki Fukutomi, Noriyuki Uchida, Yasuo Terao, Hiroki Hamada, Takahiro Muraoka, Eswaramoorthy Muthusamy, Tapas K. Kundu, Kimio Akagawa. Activator of KAT3 histone acetyltransferase family ameliorates a neurodevelopmental disorder phenotype in the syntaxin 1A ablated mouse model. Cell Reports. 2024
  • Tsutomu Yamane, Takahiro Nakayama, Toru Ekimoto, Masao Inoue, Keigo Ikezaki, Hiroshi Sekiguchi, Masahiro Kuramochi, Yasuo Terao, Ken Judai, Minoru Saito, et al. Comparison of the Molecular Motility of Tubulin Dimeric Isoforms: Molecular Dynamics Simulations and Diffracted X-ray Tracking Study. International Journal of Molecular Sciences. 2023
  • Takahiro Nakayama, Yasuo Terao, Kimio Akagawa. The role of Sp3 transcription factor in syntaxin 1A gene silencing. Gene Reports. 2022. 27
  • Takahiro Nakayama, Toshiyuki Fukutomi, Yasuo Terao, Kimio Akagawa. Syntaxin 1A Gene Is Negatively Regulated in a Cell/Tissue Specific Manner by YY1 Transcription Factor, Which Binds to the -183 to -137 Promoter Region Together with Gene Silencing Factors Including Histone Deacetylase. Biomolecules. 2021. 11. 2. 146-156
  • Hamada, H., Nakayama, T., Shimoda, K., Matsuura, N., Hamada, H., Iwaki, T., Kiriake, Y., Saikawa, T. Curcumin Oligosaccharides (Gluco-oligosaccharides) Penetrate the Blood-Brain Barrier in Mouse Brain: Glycoside (Polysaccharide) Modification Approach for Brain Drug Delivery Across the Blood-Brain Barrier and Tumor Drug Delivery. Natural Product Communications. 2020. 15. 11
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MISC (29)：
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Lectures and oral presentations  (2)：
  • Chromosomal deletion and phenotype correlation in patients with williams syndrome.
    (The 5th international symposium on etiology and morphogenesis of congenital heart disease 1998)
  • Hemizygous chromosomal deletion of the HPC-1/syntaxin 1A (STX1A) in patients referred for Williams syndrome (WS).
    (1997)
Professional career (1)：
  • Ph.D (University of Tokyo)
Work history (9)：
  • 2019/04 - 現在 Kyorin University Faculty of Medicine
  • 2017/04 - 現在 Nihon University The Institute of Natural Sciences Visiting researcher
  • 2008/04 - 2019/03 Kyorin University Faculty of Medicine
  • 2008/04 - 2012/03 RIKEN Brain Sciense Institute Visiting researcher
  • 2005/04 - 2008/03 日本学術振興会 特別研究員
Show all
Awards (1)：
  • 2011/04 - Kyorin Medical Research Award
Association Membership(s) (3)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE JAPAN NEUROSCIENCE SOCIETY
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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