Morisaka Hiroyuki

モリサカヒロユキ | Morisaka Hiroyuki

Affiliation and department：
Job title： Specially Appointed Assistant professor

Research field (2)： Dermatology , Genomics

Research keywords (6)： Genome editing , Gene editing , CRISPR , Regnase-1 , Phage , CRISPR/Cas

Research theme for competitive and other funds (7)：

2024 - 2026 全身性強皮症における表皮・真皮Regnase-1の役割解明
2021 - 2024 Therapeutic Application of CRISPR-Cas3 for dominant dystrophic Epidermolysis Bullosa
2022 - 2023 全身性強皮症の病態におけるRegnase-1の関与
2022 - 2023 Therapeutic application of CRISPR-Cas3 for Epidermolysis Bullosa
2021 - 2022 Therapeutic application of CRISPR-Cas3 for Epidermolysis Bullosa

Show all

Papers (8)：

Hiroyuki Morisaka, Hozumi Sano, Mayuko Yamamoto, Mikiro Takaishi, Hideki Nakajima, Fumiya Ogasawara, Kazuto Togitani, Mari Tashiro, Toru Kubo, Hiroko Ueda, et al. Therapeutic efficacy of allogenic haematopoietic stem cell transplantation from an appropriate sibling donor to a patient with subcutaneous panniculitis-like T-cell lymphoma with a germline homozygous HAVCR2 mutation. Journal of the European Academy of Dermatology and Venereology. 2024
Hiroyuki Morisaka, Mikiro Takaishi, Shizuo Akira, Shigetoshi Sano. Keratinocyte Regnase-1, a down-regulator of skin inflammation, contributes to protection against tumor promotion by limiting COX-2 expression. Journal of Investigative Dermatology. 2022. 143. 5. 731-739
Yuji Kadowaki, Mitsuru Nishiyama, Makoto Nakamura, Hiroyuki Morisaka, Shimpei Fujimoto, Yoshio Terada, Kensuke Kojima. Adult-onset Langerhans cell histiocytosis changing CNS lesion from pituitary to suprasellar extension. Endocrinology, diabetes & metabolism case reports. 2022. 2022
Hiroyuki Morisaka, Riho Nakajima, Yukiko Aoyama, Mika Teraishi, Hideki Nakajima, Maho Ogawa, Shigetoshi Sano. Case of pigmented skin metastasis of breast carcinoma. The Journal of Dermatology. 2021
Kimiko Nakajima, Riho Nakajima, Hiroyuki Morisaka, Hideki Nakajima, Shigetoshi Sano. Beneficial Impact of Apremilast on Palmoplantar Keratodermas. Acta dermato-venereologica. 2021

ｍore...

MISC (39)：

玉井克人, 菊池康, 森志保, 森坂広行, 外村香子, 種村篤, 藤本学. 大阪大学皮膚科における栄養障害型表皮水疱症治療法開発. 日本皮膚科学会雑誌. 2024. 134. 1. 102-102
森坂広行, 藤本学. Hailey-Hailey病の1例. 西日本皮膚科. 2023. 85. 6. 507-507
森坂広行, 佐野ほづみ, 高石樹朗, 中島英貴, 小笠原史也, 砥谷和人, 藤井伸治, 佐野栄紀. 造血幹細胞移植にて治療したHAVCR2変異皮下脂肪織炎様T細胞リンパ腫. 日本臨床皮膚科医会雑誌. 2023. 40. 3. 479-479
畠中優, 角野貴應, 森坂広行, 中島英貴, 中島喜美子, 葛目雅弓, 松本宗一. 中咽頭癌に対する放射線治療後にStevens-Johnson症候群を発症した1例. 西日本皮膚科. 2023. 85. 2. 142-142
中島里穂, 青山由貴子, 森坂広行, 中島英貴, 佐野栄紀. Microsporum canisによる汎発性浅在性白癬の1例. 西日本皮膚科. 2023. 85. 1. 56-58

ｍore...

Patents (2)：

Lectures and oral presentations (5)：

Keratinocyte Regnase-1, a down-modulator of skin inflammation, contributes to protection from carcinogenesis through regulating COX-2
(51st European Society for dermatological Research annual meeting 2022)
Keratinocyte Regnase-1, a down-modulator of skin inflammation, contributes to protection from carcinogenesis through regulating COX-2
(The 46th Annual Meeting of the Japanese Society for Investigative Dermatology 2021)
Genome editing in human cell with CRISPR-Cas3
(The 38th Annual Meeting of JAPAN HUMAN CELL SOCIETY 2020)
Possible application of broad and unidirectional genome editing using the novel CRISPR-Cas3 system for autosomal dominant Epidermolysis Bullosa
(The EB 2020 - 1st Global Congress on Epidermolysis Bullosa 2020)
CRISPR/Cas3による哺乳動物細胞でのゲノム編集
(第71回日本皮膚科学会西部支部学術大会 2019)

Education (2)：

2015 - 2020 Kochi University Graduate School of Integrated Arts and Sciences (Doctoral Course) Medicine
2005 - 2011 Kochi University Medical School Medical Course

Professional career (1)：

医学博士 (高知大学)

Work history (7)：

2023/04 - 現在 Osaka University Department of Stem Cell Gene Therapy Science, Graduate School of Medicine Specially Appointed Assistant professor
2022/07 - 2023/03 Integrated Medicine, Graduate School of Medicine, Osaka University Department of Dermatology Assistant professor
2021/10 - 2022/06 Kochi University, Kochi Medical school department of dermatology Assistant professor
2018/02 - 2021/09 Kochi University Medical School
2015/06 - 2018/01 Osaka University Graduate School of Medicine

Show all

Awards (6)：

2022/02 - Kochi university 21st KMS research meeting excellence award Keratinocyte Regnase-1, a down-modulator of skin inflammation, contributes to protection from carcinogenesis through regulating COX-2
2020/03 - 高知大学医学部附属病院研究者表彰若手優秀研究者賞
2020/02 - 第19回KMS(高知大学医学部) Research meeting 最優秀賞
2020 - Japanese Dermatological Association Seigo Minami Memorial Prize CRISPR-Cas3 induces broad and unidirectional genome editing in human cells
2020/01 - EB2020 BEST SCIENTIFIC POSTERS Possible application of broad and unidirectional genome editing using the novel CRISPR-Cas3 system for autosomal dominant Epidermolysis Bullosa

Show all

Association Membership(s) (5)：

日本乾癬学会 , The Japanese Society for Genome Editing , 日本臨床皮膚科学会 , THE JAPANESE SOCIETY FOR INVESTIGATIVE DERMATOLOGY , THE JAPANESE DERMATOLOGICAL ASSOCIATION

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page