Li Yun-Shan

Affiliation and department：

Research field (2)： Pharmacology , Home economics, lifestyle science

Research keywords (3)： nanoparticle , nutrition and health , oxidative stress

Research theme for competitive and other funds (7)：

2024 - 2027 Establishment of Mass Production Method and Functional Enhancement of Mesenchymal Stem Cells for Liver Regeneration Therapy
2021 - 2024 酸化ストレスの視点から見たメンタルストレスバイオマーカーの探索
2017 - 2022 Evaluation of 8-hydroxyguanine in saliva as an oxidative stress marker
2015 - 2018 ウメ抽出物中の糖尿病改善物質の検索
2015 - 2016 新たな酸化ストレスマーカーとしての唾液中8-OHGuaの有用性についての検討

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Papers (43)：

Hinako Nanri, Megumi Hara, Yuichiro Nishida, Chisato Shimanoe, Yun-Shan Li, Hiroshi Kasai, Kazuaki Kawai, Yasuki Higaki, Keitaro Tanaka. The Association between Oxidative Balance Score and Urinary Levels of 8-Hydroxydeoxyguanosine among Japanese Adults. Nutrients. 2023. 15. 21
Yuya Kawasaki, Yun-Shan Li, Yuko Ootsuyama, Koichi Fujisawa, Hisamitsu Omori, Ayumi Onoue, Kenichi Kubota, Toshimi Yoshino, Yoshio Nonami, Minoru Yoshida, et al. Assessment of exposure and DNA damage from second-hand smoke using potential biomarker in urine: cigarettes and heated tobacco products. Journal of clinical biochemistry and nutrition. 2023. 72. 3. 242-247
Yosuke Mano, Manabu Tsukamoto, Ke-Yong Wang, Takayuki Nabeshima, Kenji Kosugi, Takafumi Tajima, Yoshiaki Yamanaka, Hitoshi Suzuki, Makoto Kawasaki, Eiichiro Nakamura, et al. Oxidative stress causes muscle structural alterations via p38 MAPK signaling in COPD mouse model. Journal of bone and mineral metabolism. 2022. 40. 6. 927-939
Yuya Kawasaki, Yun-Shan Li, Sintaroo Watanabe, Yuko Ootsuyama, Kazuaki Kawai. Urinary biomarkers for secondhand smoke and heated tobacco products exposure. Journal of clinical biochemistry and nutrition. 2021. 69. 1. 37-43
Yun-Shan Li, Yuya Kawasaki, Sintaroo Watanabe, Yuko Ootsuyama, Hiroshi Kasai, Kazuaki Kawai. Diurnal and day-to-day variation of urinary oxidative stress marker 8-hydroxy-2'-deoxyguanosine. Journal of clinical biochemistry and nutrition. 2021. 68. 1. 18-22

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MISC (32)：

久田文, 穴井茜, 李云善, 河井一明, 葛西宏, 柚原健男, 大場隆, 加藤貴彦. 妊婦の尿中酸化ストレス指標と出生児の体重との関連. 日本衛生学雑誌. 2018. 73. Suppl. S243-S243
原めぐみ, 西田裕一郎, 福典之, 田口尚人, 島ノ江千里, 堀田美加子, 河井一明, 李云善, 葛西順, 葛西宏, et al. ミトコンドリアハプログループDが身体活動量と尿中8OHdG濃度の関連に及ぼす影響. 日本疫学会学術総会講演集(Web). 2017. 27th. 108 (WEB ONLY)
川崎祐也, 李云善, 渡邉晋太郎, 葛西宏, 河井一明. 26. 禁煙による生体内酸化ストレスの低減(第33回産業医科大学学会総会学術講演・展示抄録集). 産業医科大学雑誌. 2016. 38. 1. 96-96
渡邉晋太郎, 李云善, 川崎裕也, 本田融, 太田雅規, 大和浩, 河井一明. 27. 唾液中の酸化ストレスマーカー8-ヒドロキシグアニンの分析(第33回産業医科大学学会総会学術講演・展示抄録集). 産業医科大学雑誌. 2016. 38. 1. 97-97
李云善, 川崎祐也, 葛西宏, 河井一明. 19. グルタチオン欠乏がX線照射誘発酸化ストレスに及ぼす影響(第33回産業医科大学学会総会学術講演・展示抄録集). 産業医科大学雑誌. 2016. 38. 1. 93-93

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Lectures and oral presentations (36)：

RNA酸化損傷バイオマーカー尿中8-hydroxyguanosineの測定値変動について
(日本変異原ゲノム学会第52回大会 2023)
ライフスタイルによるDNAとRNA損傷のバイオマーカーへの影響
(第41回産業医科大学学会 2023)
概日リズム障害による酸化ストレスへの影響
(第76回日本酸化ストレス学会学術集会 2023)
サーカディアンリズム障害が生体内の酸化ストレスに及ぼす影響
(第96回日本産業衛生学会 2023)
Variations and influencing factors of urinary oxidative stress biomarker 8-hydroxy-2′-deoxyguanosine
(The 7th Asian Conference on Environmental Mutagens(7th ACEM)and the 19th Conference of Chinese Environmental Mutagen Society(19th CEMS) 2022)

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Education (3)：

2003 - 2006 Okayama University Graduate School of Natural Science & Technology
2000 - 2001 Agriculture University of Poznan Faculty of Horticulture
1996 - 1999 Yanbian University, China Faculty of Agriculture

Professional career (3)：

博士 (岡山大学)
修士 (ポーランド・ポズナン農業大学)
修士 (中国・延邊大学)

Work history (5)：

2020/09 - 現在 University of Occupational and Environmental Health, Japan Institute of Industrial Ecological Sciences Associate Professor
2017/04 - 2020/08 University of Occupational and Environmental Health Institute of Industrial Ecological Sciences Assistant Professor
2006/10 - 2017/03 University of Occupational and Environmental Health Institute of Industrial Ecological Sciences Research associate
2000/01 - 2003/08 Yanbian University, China Agriculture College Assistant Professor
1994/07 - 1999/12 Yanbian University, China Agriculture College Research Associate

Awards (6)：

2019/11 - Genes and Environment 2018 Best Paper Award Measurement of 8-hydroxyguanine as an oxidative stress biomarker in saliva by HPLC-ECD
2017/11 - The 12th International Conference & 5th Asian Congress on Environmental Mutagens with the 33rd Annual Meeting of KSOT/KEMS Best Presentation Award
2013 - 日本変異原学会学会誌優秀論文賞
2012/10 - The 3rd Asian Conference on Environmental Mutagens & 15th Cofference of Chinese Environmental Mutagen Society Best Poster Award
2010 - 日本産業医科大学学会第28回産業医科大学学会総会優秀ポスター賞

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Association Membership(s) (6)：

Antioxidant Unit研究会 , THE JAPANESE ENVIRONMENTAL MUTAGEN SOCIETY , SOCIETY FOR FREE RADICAL RESEARCH JAPAN , JAPAN SOCIETY FOR OCCUPATIONAL HEALTH , THE JAPANESE CANCER ASSOCIATION , JAPANESE SOCIETY OF OCCUPATIONAL MEDICINE AND TRAUMATOLOGY

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