Research field (4):
Oral medicine (pathology)
, Experimental pathology
, Molecular biology
, Oral medicine
Research keywords (1):
oral cancer, head and neck cancer, liver cancer, metabolism, immune-oncology, deep learning, oncovirus, organoid, tumor microenvironment
Research theme for competitive and other funds (10):
2024 - 2027 Develop the novel targets and immunotherapy-combination agents through targeting nuclear transport receptor
2024 - 2025 Development of an immune therapy and monitoring system for head and neck cancer targeting KPN7A as a molecular target
2023 - 2024 Grant-in-aid for Research Professor and Associate Professor
2023 - 2024 Grant-in-aid for Scientific Research
2019 - 2021 Periodontitis induced alterations of gut microbial metabolite promotes liver cancer through senescence
2017 - 2018 Association of periodontitis and liver diseases
2011 - 2013 Study on development of novel therapy targeting N-cadherin for oral cancer
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Papers (32):
Phuong Thao Nguyen, Yudai Shimojukkoku, Yuka Kajiya, Yasunobu Oku, Ayami Tomishima, Kaori Shima, Tomonori Sasahira. Gene alterations in the nuclear transport receptor superfamily: A study of head and neck cancer. PLOS ONE. 2024. 19. 5. e0300446-e0300446
Kaori Shima, Phuong Thao Nguyen, Yudai Shimojukkoku, Yuka Kajiya, Tomonori Sasahira. Solitary circumscribed neuroma of the upper lip: A case report. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 2023
Chanbora Chea, Mutsumi Miyauchi, Toshihiro Inubushi, Nurina Febriyanti Ayuningtyas, Ajiravudh Subarnbhesaj, Phuong Thao Nguyen, Madhu Shrestha, Sivmeng Haing, Kouji Ohta, Takashi Takata. Molecular mechanism of inhibitory effects of bovine lactoferrin on the growth of oral squamous cell carcinoma. PLoS ONE. 2018. 13. 1
Lectures and oral presentations (39):
Digital CD8+ lymphocyte density predicts overall survival of head and neck squamous cell carcinoma
(The 113th annual meeting of The Japanese Society Pathology 2024)
Novel perspectives on the infiltration of immune cells in head and neck cancer
(The 113th annual meeting of The Japanese Society Pathology 2024)
Overexpression of KPNA7 is associated with poor overall survival in head and neck cancer
(The 113th annual meeting of The Japanese Society Pathology 2024)
New insights into YAP nuclear translocation in liver tumorigenesis
(The 113th annual meeting of The Japanese Society Pathology 2024)
Accumulation of lipid droplets induces the growth of OSCC in a SCARB1-dependent manner
(The 113th annual meeting of The Japanese Society Pathology 2024)