Misako Matsubara

Affiliation and department：

Research field (1)： Cell biology

Research theme for competitive and other funds (10)：

2022 - 2025 肝細胞のがん化における細胞間相互作用を介した星細胞の役割
2021 - 2024 マウス肝癌移植モデルを利用した肝炎沈静化後ヒト肝癌再発メカニズムの解明
2021 - 2024 Elucidation of irreversible switch mechanism in hepatic stellate cell activation
2019 - 2022 Are activated stellate cells producing Cytoglobin directly involved in hepatocarcinogenesis?
2018 - 2021 Significance of hepatic stellate cell trasformation in liver cancer.

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Papers (41)：

Hanh Vinh Ngo, Thuy Thi Thanh Le, Hieu Ngoc Vu, Hai Hoang, Hiroko Ikenaga, Misako Sato-Matsubara, Sawako Uchida-Kobayashi, Hayato Urushima, Khanh Van Nguyen, Ha Thi Nguyen, et al. Poorly Differentiated Hepatocellular Carcinoma Cells Avoid Apoptosis by Interacting with T Cells via CD40-CD40L Linkage. The American journal of pathology. 2024
Truong Huu Hoang, Misako Sato-Matsubara, Hideto Yuasa, Tsutomu Matsubara, Le Thi Thanh Thuy, Hiroko Ikenaga, Dong Minh Phuong, Ngo Vinh Hanh, Vu Ngoc Hieu, Dinh Viet Hoang, et al. Cancer cells produce liver metastasis via gap formation in sinusoidal endothelial cells through proinflammatory paracrine mechanisms. Science Advances. 2022. 8. 39
Yoshinori Okina, Misako Sato-Matsubara, Yasutoshi Kido, Hayato Urushima, Atsuko Daikoku, Chiho Kadono, Yu Nakagama, Yuko Nitahara, Truong Huu Hoang, Le Thi Thanh Thuy, et al. Nitric oxide derived from cytoglobin-deficient hepatic stellate cells causes suppression of cytochrome c oxidase activity in hepatocytes. Antioxidants & redox signaling. 2022. 38. 7-9. 463-479
Minh Phuong Dong, Le Thi Thanh Thuy, Dinh Viet Hoang, Hoang Hai, Truong Huu Hoang, Misako Sato-Matsubara, Vu Ngoc Hieu, Atsuko Daikoku, Ngo Vinh Hanh, Hayato Urushima, et al. Soluble immune checkpoint protein CD27 is a novel prognostic biomarker of HCC development in HCV-SVR patients. The American journal of pathology. 2022. 192. 10. 1379-1396
Katsutoshi Yoshizato, Toshio Taira, Misako Sato-Matsubara, Shizuko Sekiguchi, Yoriko Yabunaka, Yukimi Kira, Tetsu Ohashi, Atsuko Daikoku, Ken Ofusa, Chiho Kadono, et al. Title: Cloaking the ACE2 receptor with salivary cationic proteins inhibits SARS-CoV-2 entry. Journal of biochemistry. 2022

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MISC (40)：

松原三佐子, 平敏夫, 城戸康年, 中釜悠, 河田則文, 吉里勝利. 新興感染症:新型コロナウイルスに即応する生化学〜診断・治療・疫学への越境唾液内生理活性物質の抗ウイルス効果. 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [1S10a-05]
松原三佐子. A new concept of hepatic stellate cell activation in liver fibrosis. 肝胆膵. 2021. 82. 4. 539-545
Truong Huu Hoang, 松原三佐子, 河田則文. 肝類洞内皮細胞の細胞内ギャップ形成はがん細胞の肝転移能力を促進する(Intracellular gap formation of the liver sinusoidal endothelial cells facilitates the liver metastasis ability of cancer cell). 日本消化器病学会雑誌. 2021. 118. 臨増総会. A390-A390
HUU Hoang Truong, 松原三佐子, 河田則文. Intracellular gap formation of the liver sinusoidal endothelial cells facilitates the liver metastasis ability of cancer cell. 日本消化器病学会雑誌(Web). 2021. 118
松原三佐子, 河田則文. 肝硬変の予後改善を目指した治療戦略肝硬変治療薬開発を見据えた肝星細胞活性化抑制物質の同定. 肝臓. 2020. 61. Suppl.1. A92-A92

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