Natsumeda Manabu

Affiliation and department：

Research field (1)： Neurosurgery

Research theme for competitive and other funds (13)：

2022 - 2026 Investigation of development mechanism and preemptive medicine for IDH-mutant glioma based on genomic analysis of normal brain tissues
2022 - 2025 Development of novel therapies for rare malignant brain tumors by drug screening using proprietary tumor cell lines
2021 - 2025 Chemo-sensitization of brain tumors by manipulation of SLFN11
2021 - 2024 Visualization of microenvironments of malignant glioma utilizing 7T-MRI and 3D tissue clearing technology
2019 - 2024 Iinsight into the prognosis of medulloblastoma patients with detection of 2HG on 3T-MR spectroscopy

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Papers (96)：

Haruhiko Takahashi, Manabu Natsumeda, Norikazu Hara, Akihide Koyama, Hiroshi Shimizu, Akinori Miyashita, Daiken Satake, Yoshihiro Mouri, Jun Tsukano, Keita Kawabe, et al. Missense mutation of NRAS is associated with malignant progression in neurocutaneous melanosis. Acta neuropathologica communications. 2024. 12. 1. 14-14
Jotaro On, Manabu Natsumeda, Haruhiko Takahashi, Akihide Koyama, Satoshi Shibuma, Nao Shibata, Jun Watanabe, Shoji Saito, Yu Kanemaru, Yoshihiro Tsukamoto, et al. Reliable detection of genetic alterations in cyst fluid DNA for the diagnosis of brain tumors. Journal of neuro-oncology. 2024
Dina Hesham, Jotaro On, Nouran Alshahaby, Nada Amer, Sameh Magdeldin, Masayasu Okada, Yoshihiro Tsukamoto, Tetsuya Hiraishi, Chihaya Imai, Shujiro Okuda, et al. Multi-omics analyses of choroid plexus carcinoma cell lines reveal potential targetable pathways and alterations. Journal of neuro-oncology. 2024. 166. 1. 27-38
Yoshihiro Tsukamoto, Manabu Natsumeda, Haruhiko Takahashi, Asuka Ueno, Kiichi Sakai, Kazuki Shida, Hiroki Seto, Taiki Saito, Satoshi Shibuma, Yoko Nakayama, et al. Clinical, imaging, and molecular features of radiation-induced glioblastomas developing more than 20 years after radiation therapy for intracranial germinomatous germ cell tumor: illustrative cases. Journal of neurosurgery. Case lessons. 2023. 6. 16
棗田学, 温城太郎, 渡邉潤, 塚本佳広, 岡田正康, 小倉良介, 平石哲也, 大石誠, 藤井幸彦. 【「脳神経外科領域におけるPDTの現状と問題点」】当科における光線力学療法の経験および次世代への挑戦. 日本レーザー医学会誌. 2023. 44. 2. 95-101

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MISC (157)：

棗田学, 温城太郎, 高橋陽彦, 渡邉潤, 塚本佳広, 大石誠, 柿田明美, 瀧澤淳, 正木康史, 林康彦. 脳腫瘍診断におけるliquid biopsyの可能性中枢神経再発を来すsystemic diffuse large B cell lymphomaは高率にMYD88変異を有する. Brain Tumor Pathology. 2023. 40. Suppl. 069-069
棗田学. PCNSLの診断および治療最新のトピックスを交えて. Brain Tumor Pathology. 2023. 40. Suppl. 082-082
高橋陽彦, 棗田学, 塚本佳広, 清水宏, 岡本浩一郎, 峰晴陽平, 荒川芳輝, 大石誠, 柿田明美, 藤井幸彦. FGFR3-TACC3 fusionを伴うIDH野生型神経膠腫はCTで石灰化を高率に有する. Brain Tumor Pathology. 2023. 40. Suppl. 099-099
伊師雪友, ツァン・ヨンザン, ツァン・アリ, 佐々木貴浩, 渡邊潤, 阿部幸喜, 棗田学, 山口秀, 藤村幹, 橋詰倫太郎. AT/RTのEZH2およびBRD4を標的とした新規治療. Brain Tumor Pathology. 2023. 40. Suppl. 109-109
塚本佳広, 高橋陽彦, 棗田学, 坂井貴一, 中山遥子, 田中裕貴, 岡本浩一郎, 大石誠, 柿田明美, 藤井幸彦. 胚種治療後20年以上経過後に発症した放射線誘発性膠芽腫の2症例の検討. Brain Tumor Pathology. 2023. 40. Suppl. 113-113

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Education (2)：

2007 - 2011 新潟大学医歯学総合研究科(神経病理学)
1997 - 2003 Niigata University Faculty of Medicine School of Medicine

Work history (3)：

2023/04 - 現在 Niigata University Brain Research Institute Advanced Neurological Disease Research Branch Specially Appointed Associate Professor
2013/04 - 2023/03 Niigata University Brain Research Institute
2013/09 - 2016/03 Johns Hopkins大学神経病理学分野 Postdoctoral fellow

Committee career (1)：

2019/04 - 現在日本臨床腫瘍研究グループ JCOG PRC医学審査委員

Awards (4)：

2015/03 - Johns Hopkins大学病理学部門Young Investigator Day 若手研究奨励賞
2012/07 - 第27回日本脳神経外科国際学会フォーラム最優秀発表賞
2010/08 - 第40回新潟神経学夏期セミナー中田瑞穂若手研究奨励賞
2009/09 - 新潟大学「みかんの会」若手医学研究賞

Association Membership(s) (9)：

アメリカ脳腫瘍学会 , 日本Awake Surgery学会 , THE JAPANESE SOCIETY FOR PEDIATRIC NEUROSURGERY , THE JAPAN SOCIETY FOR CNS COMPUTED IMAGING , 日本分子神経外科学会 , 日本脳腫瘍学会 , THE JAPAN SOCIETY OF BRAIN TUMOR PATHOLOGY , THE JAPANESE CONGRESS OF NEUROLOGICAL SURGEONS , THE JAPAN NEUROSURGICAL SOCIETY

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