Sugawara Kenji

Affiliation and department：
Research theme for competitive and other funds (13)：

2023 - 2026 Elucidation of the molecular mechanism and physiological significance of retrograde glucose transport in the intestine.
2022 - 2024 メトホルミンが生体内の金属動態に与える影響およびその意義の解明
2021 - 2024 メトホルミンによる腸管腔内へのグルコース排泄機構の解明
2022 - 2023 消化管における逆行性グルコース輸送機構の包括的解析
2020 - 2023 鉄キレート作用を介したメトホルミンによる新規耐糖能改善メカニズムの解明

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Papers (23)：

Quan Yingyue, Kenji Sugawara, Harumi Takahashi, Norihide Yokoi, Kento Ohbayashi, Yusaku Iwasaki, Susumu Seino, Wataru Ogawa. Stimulatory effect of imeglimin on incretin secretion. Journal of diabetes investigation. 2023. 14. 6. 746-755
Kyosuke Sato, Kenji Sugawara, Wataru Ogawa. A novel view of the insulin signaling pathway based on prediction of protein structure by the AI platform AlphaFold. Journal of diabetes investigation. 2023
Kaori Hozumi, Kenji Sugawara, Takaya Ishihara, Naotada Ishihara, Wataru Ogawa. Effects of imeglimin on mitochondrial function, AMPK activity, and gene expression in hepatocytes. Scientific reports. 2023. 13. 1. 746-746
Kenji Sugawara, Wataru Ogawa. New mechanism of metformin action mediated by lysosomal presenilin enhancer 2. Journal of diabetes investigation. 2022
Kei Yoshino, Yushi Hirota, Wataru Ogawa, Kenji Sugawara, Akira Kawaguchi, Hiroshi Yoshino, Midori Ishibashi, Gen Yoshino, Masafumi Koga. A case of α-chain variant hemoglobin (Hb Chad) with falsely high HbA1c levels measured by immunoassay. Diabetology international. 2022. 13. 1. 330-335

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MISC (80)：

穂積かおり, 菅原健二, 石原孝也, 石原直忠, 小川渉. 肝細胞におけるイメグリミンのミトコンドリア機能、AMPK活性化、遺伝子発現における効果. 日本臨床分子医学会学術総会プログラム・抄録集. 2023. 58回. 51-51
権映月, 菅原健二, 高橋晴美, 横井伯英, 大林健人, 岩崎有作, 清野進, 小川渉. インクレチン分泌に対するimegliminの効果(The effects of imeglimin on incretin secretion). 糖尿病. 2023. 66. Suppl.1. S-177
森田靖子, 坂口一彦, 野上宗伸, 曽菲比, 西坂まり華, 伊藤潤, 金子景弘, 末松那都, 山田倫子, 菅原健二, et al. 肥満は腸管内腔グルコース排泄を増強する. 糖尿病. 2023. 66. Suppl.1. S-247
伊藤潤, 坂口一彦, 野上宗伸, 金子景弘, 森田靖子, 山田倫子, 駒田久子, 菅原健二, 廣田勇士, 小川渉. 新規FDG-PET/MRI撮像法の開発によるメトホルミンの消化管ブドウ糖排泄作用の定量的分析. 日本内分泌学会雑誌. 2022. 98. 1. 311-311
伊藤潤, 坂口一彦, 野上宗伸, 金子景弘, 森田靖子, 山田倫子, 駒田久子, 菅原健二, 廣田勇士, 小川渉. 新規FDG-PET/MRI撮像法の開発によるメトホルミン服用者における腸管ブドウ糖排泄の定量的解析. 糖尿病. 2022. 65. Suppl.1. S-130

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Patents (1)：

Books (6)：

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Lectures and oral presentations (3)：

Similarity and difference of intestinal actions of metformin and imeglimin
(59th EASD Annual Meeting)
Effects of Imeglimin on Mitochondrial Function, AMPK Activation, and Gene Expression in Hepatocytes and Myocytes
(The 50th European Muscle Conference)
Quantitative analysis of metformin-induced glucose excretion in the intestine
(The 83rd American Diabetes Association Scientific Sessions.)

Professional career (1)：

Association Membership(s) (4)：

THE JAPANESE SOCIETY OF INTERNAL MEDICINE , The Japan Endocrine Society , THE JAPAN DIABETES SOCIETY , アジア糖尿病学会

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