Ryo Ito

Affiliation and department：

Research field (1)： Metabolism and endocrinology

Research theme for competitive and other funds (5)：

2021 - 2024 Understanding of sarcopenia obesity by epigenomic regulation
2019 - 2021 Regulatory mechanism of beige adipocyte-differentiation by protein phosphatase.
2016 - 2018 Understanding of molecular mechanism for overgrowth of the cells in adrenal zona glomerulosa
2016 - 2018 Innovation of novel therapeutics against diabetic nephropathy targeting ChREBP
2014 - 2016 Establishment of the isolation-method of adrenal zona gromerulosa and the analysis of CYP11B2 gene regulation.

Papers (20)：

Ryo Ito, Shiyu Xie, Myagmar Tumenjargal, Yuto Sugahara, Chaoran Yang, Hiroki Takahashi, Makoto Arai, Shin-Ichi Inoue, Aoi Uchida, Kenji Nakano, et al. Mitochondrial biogenesis in white adipose tissue mediated by JMJD1A-PGC-1 axis limits age-related metabolic disease. iScience. 2024. 27. 4. 109398-109398
Hiroki Takahashi, Ryo Ito, Yoshihiro Matsumura, Juro Sakai. Environmental factor reversibly determines cellular identity through opposing Integrators that unify epigenetic and transcriptional pathways. BioEssays : news and reviews in molecular, cellular and developmental biology. 2024. 46. 2. e2300084
Yuki Ono, Ryo Ito, Kaito Arai, Gurdeep Singh, Tsuyoshi Saitoh, Robert B Russell, Francesco Raimondi, Junken Aoki, Juro Sakai, Asuka Inoue. Chemogenetic activation of G12 signaling enhances adipose tissue browning. Signal transduction and targeted therapy. 2023. 8. 1. 307-307
Hiroki Takahashi, Ge Yang, Takeshi Yoneshiro, Yohei Abe, Ryo Ito, Chaoran Yang, Junna Nakazono, Mayumi Okamoto-Katsuyama, Aoi Uchida, Makoto Arai, et al. MYPT1-PP1β phosphatase negatively regulates both chromatin landscape and co-activator recruitment for beige adipogenesis. Nature communications. 2022. 13. 1. 5715-5715
Yoshihiro Matsumura, Ryo Ito, Ayumu Yajima, Rei Yamaguchi, Toshiya Tanaka, Takeshi Kawamura, Kenta Magoori, Yohei Abe, Aoi Uchida, Takeshi Yoneshiro, et al. Spatiotemporal dynamics of SETD5-containing NCoR-HDAC3 complex determines enhancer activation for adipogenesis. Nature communications. 2021. 12. 1. 7045-7045

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MISC (4)：

Professional career (1)：

PhD (The University of Tokyo)

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