Research field (5):
Biomedical engineering
, Pharmaceuticals - health and biochemistry
, Immunology
, Structural biochemistry
, Biophysics
Research theme for competitive and other funds (3):
2020 - 2023 Understanding the efficacy of therapeutic antibodies through their interaction with cellular receptors.
2016 - 2019 Screening and design of ligands regulating the process of protein-protein interactions based on biophysical approaches
2015 - 2018 Thermodynamic basis of life: protein-carbohydrate interaction
Papers (98):
Keisuke Kasahara, Raiji Kawade, Makoto Nakakido, Ryo Matsunaga, Hiroki Akiba, Kevin C. Entzminger, Toshiaki Maruyama, Shigeru C.J. Okumura, Jose M.M. Caaveiro, Daisuke Kuroda, et al. Unveiling the structural mechanisms behind high affinity and selectivity in phosphorylated epitope-specific rabbit antibodies. Journal of Biological Chemistry. 2024. 107989-107989
Jorge Fernandez-Perez, Akinobu Senoo, Jose M.M. Caaveiro, Makoto Nakakido, Susana de Vega, Ichiro Nakagawa, Kouhei Tsumoto. Structural basis for the ligand promiscuity of the hydroxamate siderophore binding protein FtsB from Streptococcus pyogenes. Structure. 2024
Poomraphie Nuntawong, Akinobu Senoo, Yorie Tayama, Jose M.M. Caaveiro, Satoshi Morimoto, Seiichi Sakamoto. An aptamer-based fluorometric method for the rapid berberine detection in Kampo medicines. Analytica Chimica Acta. 2024. 342930-342930
Risa Asano, Makoto Nakakido, Jorge Fernández Pérez, Tomoko Ise, Jose M.M. Caaveiro, Satoshi Nagata, Kouhei Tsumoto. Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab. Biochemical and Biophysical Research Communications. 2024. 714. 149969-149969
Amanda Mixon Blackwell, Yasaman Jami-Alahmadi, Armiyaw S. Nasamu, Shota Kudo, Akinobu Senoo, Celine Slam, Kouhei Tsumoto, James A. Wohlschlegel, Jose M. M. Caaveiro, Daniel E. Goldberg, et al. Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis. 2024
Koldo Morante, Jose M. M. Caaveiro, Kouhei Tsumoto. Lipid-Protein Partnering during Pore Formation of Fragaceatoxin C. BIOPHYSICAL JOURNAL. 2016. 110. 3. 28A-28A
Shota Kudo, Jose Caaveiro, Satoru Nagatoishi, Takao Hamakubo, Tatsuhiko Kodama, Tadashi Matsuura, Yukio Sudou, Kouhei Tsumoto. Structural and Thermodynamic Characterization of the X-Dimer of Human P-Cadherin: Implications for Homophilic Cell Adhesion. PROTEIN SCIENCE. 2014. 23. 245-246